MAB370

antibody from R&D Systems

Targeting: ACVRL1 ACVRLK1, ALK1, HHT, HHT2, ORW2

Western blot (Recommended by provider)

Antibody Data

Product number

MAB370

Provider

R&D Systems

Product name

Anti-Human ALK-1 Monoclonal Antibody (Clone 117720)

Antibody type

Monoclonal

Antigen

Mouse myeloma cell line NS0-derived recombinant human ALK-1, Asp22-Gln118

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

P37023


Isotype

IgG

Vial size

500 µg

References

Submitted references

ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.

Finnson KW, Parker WL, ten Dijke P, Thorikay M, Philip A
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008 Jun;23(6):896-906

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Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): regulation of ALK-1/endoglin pathway in endothelial cells.

Fernandez-L A, Garrido-Martin EM, Sanz-Rodriguez F, Ramirez JR, Morales-Angulo C, Zarrabeitia R, Perez-Molino A, Bernabéu C, Botella LM
Thrombosis and haemostasis 2007 Feb;97(2):254-62

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Antitumor activity of ALK1 in pancreatic carcinoma cells.

Ungefroren H, Schniewind B, Groth S, Chen WB, Müerköster SS, Kalthoff H, Fändrich F
International journal of cancer 2007 Apr 15;120(8):1641-51