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- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13807-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13807-1-AP, RRID:AB_2088759
- Product name
- DARS2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DARS2 antibody (Cat. #13807-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
DARS2 is a prognostic biomarker and correlated with immune infiltrates and cuproptosis in lung adenocarcinoma.
DARS2 promotes the occurrence of lung adenocarcinoma via the ERK/c-Myc signaling pathway.
DARS2 overexpression is associated with PET/CT metabolic parameters and affects glycolytic activity in lung adenocarcinoma.
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing.
Mitochondrial oxidative phosphorylation is impaired in TALLYHO mice, a new obesity and type 2 diabetes animal model.
Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt.
Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart.
Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein MY, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Krüger M, Frezza C, Heeren J, Trifunovic A, Pasparakis M
Nature 2024 Jan;625(7994):385-392
Nature 2024 Jan;625(7994):385-392
DARS2 is a prognostic biomarker and correlated with immune infiltrates and cuproptosis in lung adenocarcinoma.
Liu XS, Zeng J, Zhang YH, Zhang Y, Gao Y, Liu C, Pei ZJ
American journal of cancer research 2023;13(3):818-834
American journal of cancer research 2023;13(3):818-834
DARS2 promotes the occurrence of lung adenocarcinoma via the ERK/c-Myc signaling pathway.
Fang T, Jiang J, Yu W, Li R, Tian H
Thoracic cancer 2023 Dec;14(36):3511-3521
Thoracic cancer 2023 Dec;14(36):3511-3521
DARS2 overexpression is associated with PET/CT metabolic parameters and affects glycolytic activity in lung adenocarcinoma.
Liu XS, Yuan LL, Gao Y, Ming X, Zhang YH, Zhang Y, Liu ZY, Yang Y, Pei ZJ
Journal of translational medicine 2023 Aug 26;21(1):574
Journal of translational medicine 2023 Aug 26;21(1):574
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing.
Willenborg S, Sanin DE, Jais A, Ding X, Ulas T, Nüchel J, Popović M, MacVicar T, Langer T, Schultze JL, Gerbaulet A, Roers A, Pearce EJ, Brüning JC, Trifunovic A, Eming SA
Cell metabolism 2021 Dec 7;33(12):2398-2414.e9
Cell metabolism 2021 Dec 7;33(12):2398-2414.e9
Mitochondrial oxidative phosphorylation is impaired in TALLYHO mice, a new obesity and type 2 diabetes animal model.
Hunter CA, Kartal F, Koc ZC, Murphy T, Kim JH, Denvir J, Koc EC
The international journal of biochemistry & cell biology 2019 Nov;116:105616
The international journal of biochemistry & cell biology 2019 Nov;116:105616
Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt.
Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, König T, Kukat A, Trifunovic A
EMBO reports 2016 Jul;17(7):953-64
EMBO reports 2016 Jul;17(7):953-64
Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart.
Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, Trifunovic A
Cell metabolism 2014 Mar 4;19(3):458-69
Cell metabolism 2014 Mar 4;19(3):458-69
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 13807-1-AP(DARS2 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 13807-1-AP(DARS2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DARS2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DARS2. This antibody recognizes human,mouse,rat antigen. The DARS2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
