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- References [20]
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- Product number
- 16031-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16031-1-AP, RRID:AB_2180459
- Product name
- RNF2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RNF2 antibody (Cat. #16031-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Host E3 ligase RNF2 restricts African swine fever virus replication through targeting viral pA104R for its K5 site ubiquitination degradation.
RNF2 Modulates Lipid Metabolism and Inflammation in Alcohol-associated Liver Disease by Interacting with USP7.
Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery.
RNF2 promotes chondrosarcoma progression by regulating ubiquitination and degradation of CBX7.
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response.
DNA break induces rapid transcription repression mediated by proteasome-dependent RNAPII removal.
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy.
Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader.
Long non-coding RNA PRR7-AS1 promotes osteosarcoma progression via binding RNF2 to transcriptionally suppress MTUS1.
CRL4B complex-mediated H2AK119 monoubiquitination restrains Th1 and Th2 cell differentiation.
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy.
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells.
The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation.
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Knockdown of RNF2 enhances the radiosensitivity of squamous cell carcinoma in lung.
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression.
Coordinated regulation of polycomb group complexes through microRNAs in cancer.
Zhang Z, Yang J, Tian Z, Sun H, Zhang X, Zhong J, Yang S, Chen Y, Luo J, Yin H, Guan G, Niu Q
Cellular and molecular life sciences : CMLS 2026 Jan 23;83(1):96
Cellular and molecular life sciences : CMLS 2026 Jan 23;83(1):96
RNF2 Modulates Lipid Metabolism and Inflammation in Alcohol-associated Liver Disease by Interacting with USP7.
Yan Q, Fang Q, Chen Z, Chen L, Du J
International journal of biological sciences 2025;21(7):3306-3323
International journal of biological sciences 2025;21(7):3306-3323
Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery.
Liu M, Jin S, Agabiti SS, Jensen TB, Yang T, Radda JSD, Ruiz CF, Baldissera G, Rajaei M, Townsend JP, Muzumdar MD, Wang S
bioRxiv : the preprint server for biology 2024 Sep 9;
bioRxiv : the preprint server for biology 2024 Sep 9;
RNF2 promotes chondrosarcoma progression by regulating ubiquitination and degradation of CBX7.
Wu Y, Huang Z, Luo P, Xiang Z, Zhang M, Chen Z, Zhou Y, Li J
Cancer & metabolism 2024 Oct 25;12(1):30
Cancer & metabolism 2024 Oct 25;12(1):30
DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response.
Arends T, Tsuchida H, Adeyemi RO, Tapscott SJ
The Journal of cell biology 2024 May 6;223(5)
The Journal of cell biology 2024 May 6;223(5)
DNA break induces rapid transcription repression mediated by proteasome-dependent RNAPII removal.
He S, Huang Z, Liu Y, Ha T, Wu B
Cell reports 2024 Jul 23;43(7):114420
Cell reports 2024 Jul 23;43(7):114420
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
Dai W, Liu Z, Yan M, Nian X, Hong F, Zhou Z, Wang C, Fu X, Li X, Jiang M, Zhu Y, Huang Q, Lu X, Hou L, Yan N, Wang Q, Hu J, Mo W, Zhang X, Zhang L
Developmental cell 2024 Feb 26;59(4):482-495.e6
Developmental cell 2024 Feb 26;59(4):482-495.e6
PLK-3-mediated phosphorylation of BAP1 prevents diabetic retinopathy.
Qin T, Lv Y, Xi X, Wu Z
Biochemical pharmacology 2024 Aug;226:116374
Biochemical pharmacology 2024 Aug;226:116374
Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader.
Kabir M, Qin L, Luo K, Xiong Y, Sidi RA, Park KS, Jin J
Journal of medicinal chemistry 2024 Apr 25;67(8):6880-6892
Journal of medicinal chemistry 2024 Apr 25;67(8):6880-6892
Long non-coding RNA PRR7-AS1 promotes osteosarcoma progression via binding RNF2 to transcriptionally suppress MTUS1.
Chen-Xi G, Jin-Fu X, An-Quan H, Xiao Y, Ying-Hui W, Suo-Yuan L, Cong S, Tian-Ming Z, Jun S
Frontiers in oncology 2023;13:1227789
Frontiers in oncology 2023;13:1227789
CRL4B complex-mediated H2AK119 monoubiquitination restrains Th1 and Th2 cell differentiation.
Qin L, Song Y, Zhang F, Wang R, Zhou L, Jin S, Chen C, Li C, Wang M, Jiang B, Sun G, Ma C, Gong Y, Li P
Cell death and differentiation 2023 Jun;30(6):1488-1502
Cell death and differentiation 2023 Jun;30(6):1488-1502
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
Wei Y, Xiao G, Xu H, Sun X, Shi Y, Wang F, Kang J, Peng J, Zhou F
The FEBS journal 2023 Jul;290(14):3629-3645
The FEBS journal 2023 Jul;290(14):3629-3645
Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy.
Park KS, Qin L, Kabir M, Luo K, Dale B, Zhong Y, Kim A, Wang GG, Kaniskan HÜ, Jin J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2205573
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2205573
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Wang J, Ouyang X, Zhou Z, Mao S, Niu X, Li H, Xu W, Song Y, Cao J, Lai B
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119162
RNF2 Mediates Hepatic Stellate Cells Activation by Regulating ERK/p38 Signaling Pathway in LX-2 Cells.
Yan Q, Pan L, Qi S, Liu F, Wang Z, Qian C, Chen L, Du J
Frontiers in cell and developmental biology 2021;9:634902
Frontiers in cell and developmental biology 2021;9:634902
The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation.
Coker H, Wei G, Moindrot B, Mohammed S, Nesterova T, Brockdorff N
Wellcome open research 2020;5:31
Wellcome open research 2020;5:31
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Sun J, Zhu Z, Li W, Shen M, Cao C, Sun Q, Guo Z, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Knockdown of RNF2 enhances the radiosensitivity of squamous cell carcinoma in lung.
Yang J, Yu F, Guan J, Wang T, Liu C, Wang Y, Liu G, Zhu S
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Oct;97(5):589-599
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Oct;97(5):589-599
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression.
Su W, Han HH, Wang Y, Zhang B, Zhou B, Cheng Y, Rumandla A, Gurrapu S, Chakraborty G, Su J, Yang G, Liang X, Wang G, Rosen N, Scher HI, Ouerfelli O, Giancotti FG
Cancer cell 2019 Aug 12;36(2):139-155.e10
Cancer cell 2019 Aug 12;36(2):139-155.e10
Coordinated regulation of polycomb group complexes through microRNAs in cancer.
Cao Q, Mani RS, Ateeq B, Dhanasekaran SM, Asangani IA, Prensner JR, Kim JH, Brenner JC, Jing X, Cao X, Wang R, Li Y, Dahiya A, Wang L, Pandhi M, Lonigro RJ, Wu YM, Tomlins SA, Palanisamy N, Qin Z, Yu J, Maher CA, Varambally S, Chinnaiyan AM
Cancer cell 2011 Aug 16;20(2):187-99
Cancer cell 2011 Aug 16;20(2):187-99
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RNF2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RNF2. This antibody recognizes human,mouse,rat antigen. The RNF2 antibody has been validated for the following applications: ELISA, WB analysis.
