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- Product number
- ABIN393566 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ring Finger Protein 2 (RNF2) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2B4
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung.
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.
Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression.
The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1.
Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants.
Suzuki A, Iwamura C, Shinoda K, Tumes DJ, Kimura MY, Hosokawa H, Endo Y, Horiuchi S, Tokoyoda K, Koseki H, Yamashita M, Nakayama T
Journal of immunology (Baltimore, Md. : 1950) 2010 Apr 15;184(8):4510-20
Journal of immunology (Baltimore, Md. : 1950) 2010 Apr 15;184(8):4510-20
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.
Zaaroor-Regev D, de Bie P, Scheffner M, Noy T, Shemer R, Heled M, Stein I, Pikarsky E, Ciechanover A
Proceedings of the National Academy of Sciences of the United States of America 2010 Apr 13;107(15):6788-93
Proceedings of the National Academy of Sciences of the United States of America 2010 Apr 13;107(15):6788-93
Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression.
Vidal M
The International journal of developmental biology 2009;53(2-3):355-70
The International journal of developmental biology 2009;53(2-3):355-70
The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1.
Barco R, Garcia CB, Eid JE
PloS one 2009;4(4):e5060
PloS one 2009;4(4):e5060
Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants.
Wu X, Spitz MR, Lee JJ, Lippman SM, Ye Y, Yang H, Khuri FR, Kim E, Gu J, Lotan R, Hong WK
Cancer prevention research (Philadelphia, Pa.) 2009 Jul;2(7):617-24
Cancer prevention research (Philadelphia, Pa.) 2009 Jul;2(7):617-24
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Supportive validation
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