Antibody data
- Antibody Data
- Antigen structure
- References [28]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 17880-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17880-1-AP, RRID:AB_2068826
- Product name
- CAMSAP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CAMSAP2 antibody (Cat. #17880-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis.
The Golgi microtubules regulate single cell durotaxis.
WDR47 protects neuronal microtubule minus ends from katanin-mediated severing.
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
A chemical genetics approach to examine the functions of AAA proteins.
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
NC1-Peptide From Collagen α3 (IV) Chains in the Basement Membrane of Testes Regulates Spermatogenesis via p-FAK-Y407.
Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization.
Golgi-associated microtubules are fast cargo tracks and required for persistent cell migration.
Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development.
Regulation of BTB Dynamics in Spermatogenesis-Insights From the Adjudin Model.
Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity.
Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.
Structural centrosome aberrations promote non-cell-autonomous invasiveness.
APC2 controls dendrite development by promoting microtubule dynamics.
EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.
Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres.
Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk.
Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.
Sliding of centrosome-unattached microtubules defines key features of neuronal phenotype.
Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation.
Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment.
TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.
Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development.
Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.
Katanin p80 regulates human cortical development by limiting centriole and cilia number.
Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition.
Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules.
Wu S, Li L, Wu X, Wong CKC, Sun F, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21925
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21925
The Golgi microtubules regulate single cell durotaxis.
Rong Y, Yang W, Hao H, Wang W, Lin S, Shi P, Huang Y, Li B, Sun Y, Liu Z, Wu C
EMBO reports 2021 Mar 3;22(3):e51094
EMBO reports 2021 Mar 3;22(3):e51094
WDR47 protects neuronal microtubule minus ends from katanin-mediated severing.
Buijs RR, Hummel JJA, Burute M, Pan X, Cao Y, Stucchi R, Altelaar M, Akhmanova A, Kapitein LC, Hoogenraad CC
Cell reports 2021 Jul 13;36(2):109371
Cell reports 2021 Jul 13;36(2):109371
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
Wang L, Yan M, Li H, Wu S, Ge R, Wong CKC, Silvestrini B, Sun F, Cheng CY
Endocrinology 2021 Jan 1;162(1)
Endocrinology 2021 Jan 1;162(1)
A chemical genetics approach to examine the functions of AAA proteins.
Cupido T, Jones NH, Grasso MJ, Pisa R, Kapoor TM
Nature structural & molecular biology 2021 Apr;28(4):388-397
Nature structural & molecular biology 2021 Apr;28(4):388-397
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
Wu S, Lv L, Li L, Wang L, Mao B, Li J, Shen X, Ge R, Wong CKC, Sun F, Cheng CY
Endocrinology 2021 Apr 1;162(4)
Endocrinology 2021 Apr 1;162(4)
NC1-Peptide From Collagen α3 (IV) Chains in the Basement Membrane of Testes Regulates Spermatogenesis via p-FAK-Y407.
Li H, Liu S, Wu S, Ge R, Cheng CY
Endocrinology 2020 Oct 1;161(10)
Endocrinology 2020 Oct 1;161(10)
Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization.
Cao Y, Lipka J, Stucchi R, Burute M, Pan X, Portegies S, Tas R, Willems J, Will L, MacGillavry H, Altelaar M, Kapitein LC, Harterink M, Hoogenraad CC
Current biology : CB 2020 Mar 9;30(5):899-908.e6
Current biology : CB 2020 Mar 9;30(5):899-908.e6
Golgi-associated microtubules are fast cargo tracks and required for persistent cell migration.
Hao H, Niu J, Xue B, Su QP, Liu M, Yang J, Qin J, Zhao S, Wu C, Sun Y
EMBO reports 2020 Mar 4;21(3):e48385
EMBO reports 2020 Mar 4;21(3):e48385
Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development.
Nakagawa N, Plestant C, Yabuno-Nakagawa K, Li J, Lee J, Huang CW, Lee A, Krupa O, Adhikari A, Thompson S, Rhynes T, Arevalo V, Stein JL, Molnár Z, Badache A, Anton ES
Neuron 2019 Sep 4;103(5):836-852.e5
Neuron 2019 Sep 4;103(5):836-852.e5
Regulation of BTB Dynamics in Spermatogenesis-Insights From the Adjudin Model.
Mao BP, Li L, Yan M, Ge R, Lian Q, Cheng CY
Toxicological sciences : an official journal of the Society of Toxicology 2019 Nov 1;172(1):75-88
Toxicological sciences : an official journal of the Society of Toxicology 2019 Nov 1;172(1):75-88
Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity.
Farías GG, Fréal A, Tortosa E, Stucchi R, Pan X, Portegies S, Will L, Altelaar M, Hoogenraad CC
Neuron 2019 Apr 3;102(1):184-201.e8
Neuron 2019 Apr 3;102(1):184-201.e8
Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.
Pongrakhananon V, Wattanathamsan O, Takeichi M, Chetprayoon P, Chanvorachote P
Journal of cell science 2018 Oct 29;131(21)
Journal of cell science 2018 Oct 29;131(21)
Structural centrosome aberrations promote non-cell-autonomous invasiveness.
Ganier O, Schnerch D, Oertle P, Lim RY, Plodinec M, Nigg EA
The EMBO journal 2018 May 2;37(9)
The EMBO journal 2018 May 2;37(9)
APC2 controls dendrite development by promoting microtubule dynamics.
Kahn OI, Schätzle P, van de Willige D, Tas RP, Lindhout FW, Portegies S, Kapitein LC, Hoogenraad CC
Nature communications 2018 Jul 17;9(1):2773
Nature communications 2018 Jul 17;9(1):2773
EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.
Yang C, Wu J, de Heus C, Grigoriev I, Liv N, Yao Y, Smal I, Meijering E, Klumperman J, Qi RZ, Akhmanova A
The Journal of cell biology 2017 Oct 2;216(10):3179-3198
The Journal of cell biology 2017 Oct 2;216(10):3179-3198
Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres.
Goldspink DA, Rookyard C, Tyrrell BJ, Gadsby J, Perkins J, Lund EK, Galjart N, Thomas P, Wileman T, Mogensen MM
Open biology 2017 Feb;7(2)
Open biology 2017 Feb;7(2)
Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk.
Wei J, Xu H, Meng W
FEBS letters 2017 Aug;591(16):2379-2393
FEBS letters 2017 Aug;591(16):2379-2393
Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.
Noordstra I, Liu Q, Nijenhuis W, Hua S, Jiang K, Baars M, Remmelzwaal S, Martin M, Kapitein LC, Akhmanova A
Journal of cell science 2016 Nov 15;129(22):4278-4288
Journal of cell science 2016 Nov 15;129(22):4278-4288
Sliding of centrosome-unattached microtubules defines key features of neuronal phenotype.
Rao AN, Falnikar A, O'Toole ET, Morphew MK, Hoenger A, Davidson MW, Yuan X, Baas PW
The Journal of cell biology 2016 May 9;213(3):329-41
The Journal of cell biology 2016 May 9;213(3):329-41
Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation.
Yau KW, Schätzle P, Tortosa E, Pagès S, Holtmaat A, Kapitein LC, Hoogenraad CC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jan 27;36(4):1071-85
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jan 27;36(4):1071-85
Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment.
Kuijpers M, van de Willige D, Freal A, Chazeau A, Franker MA, Hofenk J, Rodrigues RJ, Kapitein LC, Akhmanova A, Jaarsma D, Hoogenraad CC
Neuron 2016 Feb 3;89(3):461-71
Neuron 2016 Feb 3;89(3):461-71
TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.
van Beuningen SFB, Will L, Harterink M, Chazeau A, van Battum EY, Frias CP, Franker MAM, Katrukha EA, Stucchi R, Vocking K, Antunes AT, Slenders L, Doulkeridou S, Sillevis Smitt P, Altelaar AFM, Post JA, Akhmanova A, Pasterkamp RJ, Kapitein LC, de Graaff E, Hoogenraad CC
Neuron 2015 Dec 16;88(6):1208-1226
Neuron 2015 Dec 16;88(6):1208-1226
Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development.
Yau KW, van Beuningen SF, Cunha-Ferreira I, Cloin BM, van Battum EY, Will L, Schätzle P, Tas RP, van Krugten J, Katrukha EA, Jiang K, Wulf PS, Mikhaylova M, Harterink M, Pasterkamp RJ, Akhmanova A, Kapitein LC, Hoogenraad CC
Neuron 2014 Jun 4;82(5):1058-73
Neuron 2014 Jun 4;82(5):1058-73
Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.
Jiang K, Hua S, Mohan R, Grigoriev I, Yau KW, Liu Q, Katrukha EA, Altelaar AF, Heck AJ, Hoogenraad CC, Akhmanova A
Developmental cell 2014 Feb 10;28(3):295-309
Developmental cell 2014 Feb 10;28(3):295-309
Katanin p80 regulates human cortical development by limiting centriole and cilia number.
Hu WF, Pomp O, Ben-Omran T, Kodani A, Henke K, Mochida GH, Yu TW, Woodworth MB, Bonnard C, Raj GS, Tan TT, Hamamy H, Masri A, Shboul M, Al Saffar M, Partlow JN, Al-Dosari M, Alazami A, Alowain M, Alkuraya FS, Reiter JF, Harris MP, Reversade B, Walsh CA
Neuron 2014 Dec 17;84(6):1240-57
Neuron 2014 Dec 17;84(6):1240-57
Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition.
Syred HM, Welburn J, Rappsilber J, Ohkura H
Molecular & cellular proteomics : MCP 2013 Nov;12(11):3135-47
Molecular & cellular proteomics : MCP 2013 Nov;12(11):3135-47
Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules.
Tanaka N, Meng W, Nagae S, Takeichi M
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 4;109(49):20029-34
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 4;109(49):20029-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 17880-1-AP(CAMSAP1L1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17880-1-AP(CAMSAP1L1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CAMSAP1L1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CAMSAP1L1. This antibody recognizes human, mouse, rat antigen. The CAMSAP1L1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.