orb66907

antibody from Biorbyt

Targeting: KDM5B CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A

Western blot (Data presented on provider website)

Antibody Data

Product number

orb66907

Provider

Biorbyt

Product name

KDM5B antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to KDM5B.Lysine (K)-specific demethylase 5B (KDM5B) is a ubiquitously expressed nuclear protein. It is ahistone demethylase that specifically demethylates Lys-4 of histone H3. It can demethylatetrimethylated, dimethylated, and monomethylated Lys-4. It acts as a transcriptional corepressor forFOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressorgenes such as BRAC1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor formelanoma.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C