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LearnMA5-24626
antibody from Invitrogen Antibodies
Targeting: KDM5B
CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunocytochemistry [2]
- Immunohistochemistry [6]
- Other assay [1]
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- Product number
- MA5-24626 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- KDM5B Monoclonal Antibody (CL1129)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: DGINSLERKL KRRLEREGLS SERWERVKKM RTPKKKKIKL SHPKDMNNFK LERERSYELV RSAETHSLPS DTSYSEQEDS E Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 91%. Binds to an epitope located within the peptide sequence DGINSLERKLKRRLE as determined by overlapping synthetic peptides.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- CL1129
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references KDM5B overexpression predicts a poor prognosis in patients with squamous cell carcinoma of the head and neck.
Huang D, Qiu Y, Li G, Liu C, She L, Zhang D, Chen X, Zhu G, Zhang X, Tian Y, Liu Y
Journal of Cancer 2018;9(1):198-204
Journal of Cancer 2018;9(1):198-204
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunocytochemistry-Immunofluorescence analysis of KDM5B in MCF7 cells using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626), showing specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorecent analysis of KDM5B in MCF7 cells using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626). Staining shows specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of KDM5B in human colorectal cancer using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626) shows moderate nuclear positivity in tumor cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of KDM5B in human breast cancer using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626) shows moderate nuclear positivity in tumor cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of KDM5B in human fallopian tube using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626) shows moderate nuclear positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of KDM5B in human liver using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626) shows no positivity in hepatocytes as expected.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of KDM5B in human rectum using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626) shows moderate nuclear positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of KDM5B in human testis using KDM5B Monoclonal Antibody (CL1129) (Product # MA5-24626) shows strong nuclear positivity in cells in seminiferous ducts.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
