Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- MAB759 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse Tyro3/Dtk Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse Tyro3/Dtk extracellular domain in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tyro3/Dtk, recombinant mouse (rm) Mer, or rmAxl is observed.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
P55144
- Isotype
- IgG
- Antibody clone number
- 109646
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer.
The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.
GAS6 receptor status is associated with dormancy and bone metastatic tumor formation.
Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.
Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells.
Kasikara C, Davra V, Calianese D, Geng K, Spires TE, Quigley M, Wichroski M, Sriram G, Suarez-Lopez L, Yaffe MB, Kotenko SV, De Lorenzo MS, Birge RB
Cancer research 2019 May 15;79(10):2669-2683
Cancer research 2019 May 15;79(10):2669-2683
The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.
Fujimori T, Grabiec AM, Kaur M, Bell TJ, Fujino N, Cook PC, Svedberg FR, MacDonald AS, Maciewicz RA, Singh D, Hussell T
Mucosal immunology 2015 Sep;8(5):1021-1030
Mucosal immunology 2015 Sep;8(5):1021-1030
GAS6 receptor status is associated with dormancy and bone metastatic tumor formation.
Taichman RS, Patel LR, Bedenis R, Wang J, Weidner S, Schumann T, Yumoto K, Berry JE, Shiozawa Y, Pienta KJ
PloS one 2013;8(4):e61873
PloS one 2013;8(4):e61873
Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.
Deng T, Zhang Y, Chen Q, Yan K, Han D
Immunology 2012 Jan;135(1):40-50
Immunology 2012 Jan;135(1):40-50
Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells.
Shang T, Zhang X, Wang T, Sun B, Deng T, Han D
Endocrinology 2011 Jul;152(7):2827-36
Endocrinology 2011 Jul;152(7):2827-36
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