Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS5772 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- KV10.1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 762-807 of Human KV10.1.
- Description
- Voltage-gated potassium channels play an essential role in controlling cellular excitability in the nervous system. They regulate a variety of properties including membrane potential as well as the frequency and structure of action potentials. KCNH1 (potassium voltage-gated channel, subfamily H (eag-related), member 1), also known as ether-a-go-go potassium channel 1, voltage-gated potassium channel subunit Kv10.1, EAG, EAG1 or h-eag, is a 989 amino acid multi-pass membrane protein belonging to the potassium channel family and H (Eag) subfamily. KCNH1 is highly expressed in myoblasts and brain, forms two alternatively spliced isoforms and exists as a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. Encoded by a gene located on human chromosome 1, KCNH1 forms a heteromultimer with KCNH5 and also interacts with ALG10.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of KV10.1 pAb at 1:500 dilutionLane1:Hela cell lysateLane2:NIH-3T3 cell lysateLane3:H9C2 cell lysate