Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 21552-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21552-1-AP, RRID:AB_10732726
- Product name
- MARK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MARK1 antibody (Cat. #21552-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MARK1 regulates dendritic spine morphogenesis and cognitive functions in vivo.
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Metformin reduces neuroinflammation and improves cognitive functions after traumatic brain injury.
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.
Loss of Par1b/MARK2 primes microglia during brain development and enhances their sensitivity to injury.
Postsynaptic density 95 (PSD-95) serine 561 phosphorylation regulates a conformational switch and bidirectional dendritic spine structural plasticity.
DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants.
MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism.
An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.
Kelly-Castro EC, Shear R, Dindigal AH, Bhagwat M, Zhang H
bioRxiv : the preprint server for biology 2023 Dec 4;
bioRxiv : the preprint server for biology 2023 Dec 4;
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, Mercenne G, Banks CJ, Valdoz J, Whatcott CJ, Foulks JM, Bearss DJ, O'Hare T, Huang DCS, Christensen KA, Moody J, Warner SL, Tyner JW, Andersen JL
Nature communications 2021 Sep 9;12(1):5337
Nature communications 2021 Sep 9;12(1):5337
Metformin reduces neuroinflammation and improves cognitive functions after traumatic brain injury.
DiBona VL, Shah MK, Krause KJ, Zhu W, Voglewede MM, Smith DM, Crockett DP, Zhang H
Neuroscience research 2021 Nov;172:99-109
Neuroscience research 2021 Nov;172:99-109
Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression.
Ayanlaja AA, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, Zhang L, Xiong Y, Kambey PA, Gao D
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
Cell communication and signaling : CCS 2020 Feb 12;18(1):24
MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.
Tang X, Yang M, Wang Z, Wu X, Wang D
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):661-668
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):661-668
Loss of Par1b/MARK2 primes microglia during brain development and enhances their sensitivity to injury.
DiBona VL, Zhu W, Shah MK, Rafalia A, Ben Cheikh H, Crockett DP, Zhang H
Journal of neuroinflammation 2019 Jan 17;16(1):11
Journal of neuroinflammation 2019 Jan 17;16(1):11
Postsynaptic density 95 (PSD-95) serine 561 phosphorylation regulates a conformational switch and bidirectional dendritic spine structural plasticity.
Wu Q, Sun M, Bernard LP, Zhang H
The Journal of biological chemistry 2017 Sep 29;292(39):16150-16160
The Journal of biological chemistry 2017 Sep 29;292(39):16150-16160
DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants.
Kwan V, Meka DP, White SH, Hung CL, Holzapfel NT, Walker S, Murtaza N, Unda BK, Schwanke B, Yuen RKC, Habing K, Milsom C, Hope KJ, Truant R, Scherer SW, Calderon de Anda F, Singh KK
Cell reports 2016 Nov 8;17(7):1892-1904
Cell reports 2016 Nov 8;17(7):1892-1904
MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism.
Bernard LP, Zhang H
PloS one 2015;10(5):e0124816
PloS one 2015;10(5):e0124816
An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.
Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ
Molecular cell 2014 Aug 7;55(3):436-50
Molecular cell 2014 Aug 7;55(3):436-50
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The MARK1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MARK1. This antibody recognizes human, mouse, rat antigen. The MARK1 antibody has been validated for the following applications: ELISA, WB analysis.