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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362423 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (pTyr515) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr515 (P-Q-Y (p) -F-G) derived from Human TrkB. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr515
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Sex-specific and region-specific changes in BDNF-TrkB signalling in the hippocampus of 5-HT1A receptor and BDNF single and double mutant mice.
The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.
Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase.
Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors.
BDNF-mediated enhancement of inflammation and injury in the aging heart.
Identification and characterization of compounds that potentiate NT-3-mediated Trk receptor activity.
Wu YC, Hill RA, Klug M, van den Buuse M
Brain research 2012 May 3;1452:10-7
Brain research 2012 May 3;1452:10-7
The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.
Li N, Liu GT
Acta pharmacologica Sinica 2010 Mar;31(3):265-72
Acta pharmacologica Sinica 2010 Mar;31(3):265-72
Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase.
Woronowicz A, Amith SR, De Vusser K, Laroy W, Contreras R, Basta S, Szewczuk MR
Glycobiology 2007 Jan;17(1):10-24
Glycobiology 2007 Jan;17(1):10-24
Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors.
Mojsilovic-Petrovic J, Jeong GB, Crocker A, Arneja A, David S, Russell DS, Kalb RG
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Sep 6;26(36):9250-63
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Sep 6;26(36):9250-63
BDNF-mediated enhancement of inflammation and injury in the aging heart.
Cai D, Holm JM, Duignan IJ, Zheng J, Xaymardan M, Chin A, Ballard VL, Bella JN, Edelberg JM
Physiological genomics 2006 Feb 14;24(3):191-7
Physiological genomics 2006 Feb 14;24(3):191-7
Identification and characterization of compounds that potentiate NT-3-mediated Trk receptor activity.
Lewis MA, Hunihan L, Franco D, Robertson B, Palmer J, Laurent DR, Balasubramanian BN, Li Y, Westphal RS
Molecular pharmacology 2006 Apr;69(4):1396-404
Molecular pharmacology 2006 Apr;69(4):1396-404
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