Antibody data
- Antibody Data
- Antigen structure
- References [28]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 19999-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19999-1-AP, RRID:AB_10646467
- Product name
- TGF beta 2-Specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TGF beta 2-Specific antibody (Cat. #19999-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references tRNA-Derived Fragment tRF-Glu-TTC-027 Regulates the Progression of Gastric Carcinoma via MAPK Signaling Pathway.
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Exosome-transmitted circCOG2 promotes colorectal cancer progression via miR-1305/TGF-β2/SMAD3 pathway.
Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.
USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription.
SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions.
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase.
LncRNA PART1 promotes cell proliferation and progression in non-small-cell lung cancer cells via sponging miR-17-5p.
Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling.
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis.
miR-618 Suppresses Metastasis in Gastric Cancer by Downregulating the Expression of TGF-β2.
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Expression of miR-181a and TGF-β2 in lens epithelial cells of patients with cataractous retinal detachment and its clinical significance.
LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII-p38MAPK-pS249/T252RB Pathway.
Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes.
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGFβ2 feedback loop.
Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer.
Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation.
TGF-β2 is involved in the preservation of the chondrocyte phenotype under hypoxic conditions.
SIX1 promotes tumor lymphangiogenesis by coordinating TGFβ signals that increase expression of VEGF-C.
Participation of miR-200a in TGF-β1-mediated hepatic stellate cell activation.
Xu W, Zhou B, Wang J, Tang L, Hu Q, Wang J, Chen H, Zheng J, Yan F, Chen H
Frontiers in oncology 2021;11:733763
Frontiers in oncology 2021;11:733763
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Yong W, Zhao Y, Jiang X, Li P
Journal of applied microbiology 2021 Sep 1;
Journal of applied microbiology 2021 Sep 1;
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Meng L, Zheng Y, Liu S, Ju Y, Ren S, Sang Y, Zhu Y, Gu L, Liu F, Zhao Y, Zhang X, Sang M
Cancer letters 2021 Oct 28;519:117-129
Cancer letters 2021 Oct 28;519:117-129
Exosome-transmitted circCOG2 promotes colorectal cancer progression via miR-1305/TGF-β2/SMAD3 pathway.
Gao L, Tang X, He Q, Sun G, Wang C, Qu H
Cell death discovery 2021 Oct 11;7(1):281
Cell death discovery 2021 Oct 11;7(1):281
Cadmium promotes apoptosis and inflammation via the circ08409/miR-133a/TGFB2 axis in bovine mammary epithelial cells and mouse mammary gland.
Chen Z, Liang Y, Lu Q, Nazar M, Mao Y, Aboragah A, Yang Z, Loor JJ
Ecotoxicology and environmental safety 2021 Oct 1;222:112477
Ecotoxicology and environmental safety 2021 Oct 1;222:112477
USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription.
Jie X, Fong WP, Zhou R, Zhao Y, Zhao Y, Meng R, Zhang S, Dong X, Zhang T, Yang K, Wu G, Xu S
Cell death and differentiation 2021 Jul;28(7):2095-2111
Cell death and differentiation 2021 Jul;28(7):2095-2111
SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions.
Lin Y, Xiao Y, Lin C, Zhang Q, Zhang S, Pei F, Liu H, Chen Z
Stem cells (Dayton, Ohio) 2021 Feb;39(2):196-209
Stem cells (Dayton, Ohio) 2021 Feb;39(2):196-209
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Zhou B, Zhou Y, Liu Y, Zhang H, Mao H, Peng M, Xu A, Li Z, Wang H, Tan H, Ren H, Zhou X, Long Y
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase.
Wang ZD, Feng Y, Sun L, Gan J, Li X, Ding WF, Chen XM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111241
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Apr;136:111241
LncRNA PART1 promotes cell proliferation and progression in non-small-cell lung cancer cells via sponging miR-17-5p.
Chen Y, Zhou X, Huang C, Li L, Qin Y, Tian Z, He J, Liu H
Journal of cellular biochemistry 2021 Apr;122(3-4):315-325
Journal of cellular biochemistry 2021 Apr;122(3-4):315-325
Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling.
Huang N, Liu Y, Fang Y, Zheng S, Wu J, Wang M, Zhong W, Shi M, Xing M, Liao W
ACS nano 2020 Jul 28;14(7):7940-7958
ACS nano 2020 Jul 28;14(7):7940-7958
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
Ye S, Chen Q, Jiang N, Liang X, Li J, Zong R, Huang C, Qiu Y, Ma JX, Liu Z
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis.
Liang JN, Zou X, Fang XH, Xu JD, Xiao Z, Zhu JN, Li H, Yang J, Zeng N, Yuan SJ, Pan R, Fu YH, Zhang M, Luo JF, Wang S, Shan ZX
Biochimica et biophysica acta. Molecular basis of disease 2019 Sep 1;1865(9):2441-2450
Biochimica et biophysica acta. Molecular basis of disease 2019 Sep 1;1865(9):2441-2450
miR-618 Suppresses Metastasis in Gastric Cancer by Downregulating the Expression of TGF-β2.
Shi J, Gong L, Chen L, Luo J, Song G, Xu J, Lv Z, Tao H, Xia Y, Ye Z
Anatomical record (Hoboken, N.J. : 2007) 2019 Jun;302(6):931-940
Anatomical record (Hoboken, N.J. : 2007) 2019 Jun;302(6):931-940
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.
Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, Chen X, Yu X, Sun L, Yu X
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Journal of cellular and molecular medicine 2019 Jun;23(6):4229-4243
Expression of miR-181a and TGF-β2 in lens epithelial cells of patients with cataractous retinal detachment and its clinical significance.
Jiang Y, Gong Y, Lin N, Qiu W
Experimental and therapeutic medicine 2019 Jun;17(6):4435-4440
Experimental and therapeutic medicine 2019 Jun;17(6):4435-4440
LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.
Luo K, Geng J, Zhang Q, Xu Y, Zhou X, Huang Z, Shi KQ, Pan C, Wu J
Journal of experimental & clinical cancer research : CR 2019 Jun 11;38(1):249
Journal of experimental & clinical cancer research : CR 2019 Jun 11;38(1):249
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
Zhao Z, Shen W, Zhu H, Lin L, Jiang G, Zhu Y, Song H, Wu L
Drug design, development and therapy 2018;12:3021-3031
Drug design, development and therapy 2018;12:3021-3031
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Zhang R, Wei YH, Zhao CY, Song HY, Shen N, Cui X, Gao X, Qi ZT, Zhong M, Shen W
International journal of ophthalmology 2018;11(1):18-24
International journal of ophthalmology 2018;11(1):18-24
Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII-p38MAPK-pS249/T252RB Pathway.
Yu-Lee LY, Yu G, Lee YC, Lin SC, Pan J, Pan T, Yu KJ, Liu B, Creighton CJ, Rodriguez-Canales J, Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE, Lin SH
Cancer research 2018 Jun 1;78(11):2911-2924
Cancer research 2018 Jun 1;78(11):2911-2924
Modulation of TGF‑β activity by latent TGF‑β‑binding protein 1 in human osteoarthritis fibroblast‑like synoviocytes.
Wang X, Dong C, Li N, Ma Q, Yun Z, Cai C, An M, Ma B
Molecular medicine reports 2018 Jan;17(1):1893-1900
Molecular medicine reports 2018 Jan;17(1):1893-1900
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
Cai Y, Ma W, Xiao Y, Wu B, Li X, Liu F, Qiu J, Zhang G
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGFβ2 feedback loop.
Lei K, Liang X, Gao Y, Xu B, Xu Y, Li Y, Tao Y, Shi W, Liu J
Biochemical and biophysical research communications 2017 Mar 11;484(3):514-521
Biochemical and biophysical research communications 2017 Mar 11;484(3):514-521
Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer.
Lin SC, Lee YC, Yu G, Cheng CJ, Zhou X, Chu K, Murshed M, Le NT, Baseler L, Abe JI, Fujiwara K, deCrombrugghe B, Logothetis CJ, Gallick GE, Yu-Lee LY, Maity SN, Lin SH
Developmental cell 2017 Jun 5;41(5):467-480.e3
Developmental cell 2017 Jun 5;41(5):467-480.e3
Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation.
Li Z, Wang Z, Yin Z, Zhang Y, Xue X, Han J, Zhu Y, Zhang J, Emmert MY, Wang H
Oncotarget 2017 Aug 8;8(32):53714-53729
Oncotarget 2017 Aug 8;8(32):53714-53729
TGF-β2 is involved in the preservation of the chondrocyte phenotype under hypoxic conditions.
Das R, Timur UT, Edip S, Haak E, Wruck C, Weinans H, Jahr H
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2015 Mar;198:1-10
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2015 Mar;198:1-10
SIX1 promotes tumor lymphangiogenesis by coordinating TGFβ signals that increase expression of VEGF-C.
Liu D, Li L, Zhang XX, Wan DY, Xi BX, Hu Z, Ding WC, Zhu D, Wang XL, Wang W, Feng ZH, Wang H, Ma D, Gao QL
Cancer research 2014 Oct 1;74(19):5597-607
Cancer research 2014 Oct 1;74(19):5597-607
Participation of miR-200a in TGF-β1-mediated hepatic stellate cell activation.
Sun X, He Y, Ma TT, Huang C, Zhang L, Li J
Molecular and cellular biochemistry 2014 Mar;388(1-2):11-23
Molecular and cellular biochemistry 2014 Mar;388(1-2):11-23
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 19999-1-AP(TGFB2-Specific antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 19999-1-AP(TGFB2-Specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TGF-beta 2-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human TGF-beta 2-Specific. This antibody recognizes human,mouse,rat antigen. The TGF-beta 2-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.