BS6397

antibody from Bioworld Technology, Inc
Targeting: MAP3K7 MEKK7, TAK1
Provider product page for BS6397
Western blot

Antibody data

Product number
BS6397 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Tak1 / MAP3K7 (phospho S439) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human Tak1 / MAP3K7 around the phosphorylation site of Serine 439.
Description
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 is a protein with intrinsic kinase activity towards serine/threonine residues and that is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGF?-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGF? stimulation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MAP3K7 protein structure - BS6397 shown in red.