Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB2322 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2322, RRID:AB_1577179
- Product name
- MAP3K7 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MAP3K7.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway.
Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha.
A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta.
Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, Doi T, Saiki I
The Journal of biological chemistry 2003 Sep 19;278(38):36916-23
The Journal of biological chemistry 2003 Sep 19;278(38):36916-23
Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha.
Cheung PC, Campbell DG, Nebreda AR, Cohen P
The EMBO journal 2003 Nov 3;22(21):5793-805
The EMBO journal 2003 Nov 3;22(21):5793-805
A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta.
Ono K, Ohtomo T, Ninomiya-Tsuji J, Tsuchiya M
Biochemical and biophysical research communications 2003 Jul 25;307(2):332-7
Biochemical and biophysical research communications 2003 Jul 25;307(2):332-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of MAP3K7 polyclonal antibody (Cat # PAB2322) in HL-60 cell lysate. MAP3K7 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the MAP3K7 polyclonal antibody (Cat # PAB2322) at a 1 : 50 dilution, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)