ABIN358312

antibody from antibodies-online

Targeting: MAP3K7 MEKK7, TAK1

No application information provided.

Antibody Data

Product number

ABIN358312

Provider

antibodies-online

Product name

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pSer192) antibody

Antibody type

Polyclonal

Description

Protein A Chromatography followed by two-step phosphospecific peptide affinity purification

Reactivity

Human

Host

Rabbit

Epitope

pSer192

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Wnt activates the Tak1/Nemo-like kinase pathway.

Smit L, Baas A, Kuipers J, Korswagen H, van de Wetering M, Clevers H
The Journal of biological chemistry 2004 Apr 23;279(17):17232-40

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Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway.

Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, Doi T, Saiki I
The Journal of biological chemistry 2003 Sep 19;278(38):36916-23

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Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha.

Cheung PC, Campbell DG, Nebreda AR, Cohen P
The EMBO journal 2003 Nov 3;22(21):5793-805

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A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta.

Ono K, Ohtomo T, Ninomiya-Tsuji J, Tsuchiya M
Biochemical and biophysical research communications 2003 Jul 25;307(2):332-7

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Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3.

Edlund S, Bu S, Schuster N, Aspenström P, Heuchel R, Heldin NE, ten Dijke P, Heldin CH, Landström M
Molecular biology of the cell 2003 Feb;14(2):529-44