67707-1-Ig

antibody from Proteintech Group

Targeting: MAP3K7 MEKK7, TAK1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67707-1-Ig

Provider

Proteintech Group

Product name

MAP3K7 antibody

Antibody type

Monoclonal

Description

MAP3K7 antibody (Cat. #67707-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1A5B2

Vial size

20ul, 150ul

References

Submitted references

Finerenone improves doxorubicin-induced cardiotoxicity by inhibiting cardiomyocyte apoptosis through the TAK1-p38 axis.

Lai X, Wang Y, Zhang J, Xie H, Wu S, Wang L
Biochemical pharmacology 2026 Jul;249:117877

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Chinese medicine formula "Qingxuan Runmu Yin" alleviating ocular surface inflammation in a rat model of dry eye disease by modulating the TLR4/TAK1/p38MAPK pathway.

Liu Y, Zhao SS, Wang JD, Yao J
International journal of ophthalmology 2025;18(11):2022-2030

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ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity.

Zhang T, Wang Y, Nie X, Chen X, Jin Y, Sun L, Yang R, Wang J, Xu W, Song T, Xie W, Chen X, Li C, Zhou J, Wu S, Li Y, Li T
Cell reports 2025 Mar 25;44(3):115397

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Transforming Growth Factor-β-Activated Protein 1 (TAK1) Regulates Necroptosis in Age-Related Hearing Loss.

Wang H, Lv Y, Zhao H, Hao Z, Zhai X, Wang Y, Qiu J, Chen L, Zhou J, Cui L, Sun Y
Aging cell 2025 Jun;24(6):e70013

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Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.

Zhang X, Su Y, Yang W, Song Z, Sun Z, Wu X, Chen J, Gao B, Wang Z, Wang L, Jiang Q, Bu L, Li J, Lin Y, Xie W, Li J, Guo J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e06201

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Deubiquitinase USP18 inhibits hepatic stellate cells activation and alleviates liver fibrosis via regulation of TAK1 activity.

Zhang Y, Gao J, Liu Y, Zhong L, He S, Qiu C
Experimental cell research 2024 Oct 1;442(2):114235

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Kongensin a attenuates intervertebral disc degeneration by inhibiting TAK1-mediated PANoptosis of nucleus pulposus cells.

Chen Y, Hu B, Ni F, Han Y, Shu S, Xiong L, Shao Z, Wei Y
International immunopharmacology 2024 Mar 10;129:111661

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Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-κB signaling pathway through modification of the Src/TRAF6/TAK1 axis.

Chen H, Liu F, Dai D, Ming Y, Xu Y, Huang Z, Zhang L, Sun Y
Inflammopharmacology 2024 Apr;32(2):1475-1488

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TRIM44 aggravates cardiac fibrosis after myocardial infarction via TAK1 stabilization.

Qian H, Lu Z, Hao C, Zhao Y, Bo X, Hu Y, Zhang Y, Yao Y, Ma G, Chen L
Cellular signalling 2023 Sep;109:110744

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IL-17 promotes melanoma through TRAF2 as a scaffold protein recruiting PIAS2 and ELAVL1 to induce EPHA5.

Du J, Du Y, Chen L, Liu H
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119547

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USP4 promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting TAK1.

Zhang H, Han Y, Xiao W, Gao Y, Sui Z, Ren P, Meng F, Tang P, Yu Z
Cell death & disease 2023 Nov 10;14(11):730

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Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK.

Sun X, Li X, Zhou Y, Wang Y, Liu X
Neurochemical research 2022 Oct;47(10):3167-3177