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- References [13]
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- Product number
- 19886-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19886-1-AP, RRID:AB_10641986
- Product name
- PHD2/EGLN1 antibody
- Antibody type
- Polyclonal
- Description
- PHD2/EGLN1 antibody (Cat. #19886-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
HIF-1α/m(6)A/NF-κB/CCL3 axis-mediated immunosurveillance participates in low level benzene-related erythrohematopoietic development toxicity.
Silencing of OGDHL promotes liver cancer metastasis by enhancing hypoxia inducible factor 1 α protein stability.
Chronic constant light exposure aggravates high fat diet-induced renal injury in rats.
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue.
Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARγ pathway.
Stabilization of hypoxia-inducible factor-1α alleviates osteoarthritis via interacting with Per2 and resetting the circadian clock.
The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1α pathway.
Sustained Hypoxia Suppresses Joint Destruction in a Rat Model of Rheumatoid Arthritis via Negative Feedback of Hypoxia Inducible Factor-1α.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein.
Feng S, Ding B, Dai Z, Yin H, Ding Y, Liu S, Zhang K, Lin H, Xiao Z, Shen Y
Journal of translational medicine 2024 Mar 15;22(1):280
Journal of translational medicine 2024 Mar 15;22(1):280
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Mao Y, Zhang J, Zhou Q, He X, Zheng Z, Wei Y, Zhou K, Lin Y, Yu H, Zhang H, Zhou Y, Lin P, Wu B, Yuan Y, Zhao J, Xu W, Zhao S
Cell research 2024 Jan;34(1):13-30
Cell research 2024 Jan;34(1):13-30
HIF-1α/m(6)A/NF-κB/CCL3 axis-mediated immunosurveillance participates in low level benzene-related erythrohematopoietic development toxicity.
Cong X, Li X, Xu K, Yin L, Liang G, Sun R, Pu Y, Zhang J
Environment international 2024 Feb;184:108493
Environment international 2024 Feb;184:108493
Silencing of OGDHL promotes liver cancer metastasis by enhancing hypoxia inducible factor 1 α protein stability.
Dai W, Li Y, Sun W, Ji M, Bao R, Chen J, Xu S, Dai Y, Chen Y, Liu W, Ge C, Sun W, Mo W, Guo C, Xu X
Cancer science 2023 Apr;114(4):1309-1323
Cancer science 2023 Apr;114(4):1309-1323
Chronic constant light exposure aggravates high fat diet-induced renal injury in rats.
Xing L, Wu S, Shi Y, Yue F, Wei L, Russell R, Zhang D
Frontiers in endocrinology 2022;13:900392
Frontiers in endocrinology 2022;13:900392
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
Xu H, Zhao J, Li J, Zhu Z, Cui Z, Liu R, Lu R, Yao Z, Xu Q
Cell death & disease 2022 May 20;13(5):478
Cell death & disease 2022 May 20;13(5):478
A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue.
Zhang S, Gong F, Liu J, Liu T, Yang J, Hu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113004
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113004
Iron increases lipid deposition via oxidative stress-mediated mitochondrial dysfunction and the HIF1α-PPARγ pathway.
Song CC, Pantopoulos K, Chen GH, Zhong CC, Zhao T, Zhang DG, Luo Z
Cellular and molecular life sciences : CMLS 2022 Jul 4;79(7):394
Cellular and molecular life sciences : CMLS 2022 Jul 4;79(7):394
Stabilization of hypoxia-inducible factor-1α alleviates osteoarthritis via interacting with Per2 and resetting the circadian clock.
Wang C, Zhang Y, Wang Z, Yu W, Tong M, Yan Z
Tissue & cell 2022 Dec;79:101942
Tissue & cell 2022 Dec;79:101942
The DpdtbA induced EMT inhibition in gastric cancer cell lines was through ferritinophagy-mediated activation of p53 and PHD2/hif-1α pathway.
Guan D, Li C, Li Y, Li Y, Wang G, Gao F, Li C
Journal of inorganic biochemistry 2021 May;218:111413
Journal of inorganic biochemistry 2021 May;218:111413
Sustained Hypoxia Suppresses Joint Destruction in a Rat Model of Rheumatoid Arthritis via Negative Feedback of Hypoxia Inducible Factor-1α.
Kaihara K, Nakagawa S, Arai Y, Inoue H, Tsuchida S, Fujii Y, Kamada Y, Kishida T, Mazda O, Takahashi K
International journal of molecular sciences 2021 Apr 9;22(8)
International journal of molecular sciences 2021 Apr 9;22(8)
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein.
Cilenti L, Di Gregorio J, Ambivero CT, Andl T, Liao R, Zervos AS
Scientific reports 2020 Jan 31;10(1):1609
Scientific reports 2020 Jan 31;10(1):1609
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PHD2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PHD2. This antibody recognizes human,mouse,rat antigen. The PHD2 antibody has been validated for the following applications: ELISA, WB analysis.
