MAB397

antibody from R&D Systems

Targeting: NTRK2 TRKB

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

MAB397

Provider

R&D Systems

Product name

Anti-Human TrkB Monoclonal Antibody (Clone 75133)

Antibody type

Monoclonal

Antigen

Mouse myeloma cell line NS0-derived recombinant human TrkB, Cys32-His430

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Antigen sequence

Q16620


Isotype

IgG

Vial size

500 µg

References

Submitted references

Brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer.

Tanaka K, Okugawa Y, Toiyama Y, Inoue Y, Saigusa S, Kawamura M, Araki T, Uchida K, Mohri Y, Kusunoki M
PloS one 2014;9(5):e96410

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Brain-derived neurotrophic factor is increased in serum and skin levels of patients with chronic spontaneous urticaria.

Rössing K, Novak N, Mommert S, Pfab F, Gehring M, Wedi B, Kapp A, Raap U
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011 Oct;41(10):1392-9

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Modulation of neurotrophin and neurotrophin receptor expression in nasal mucosa after nasal allergen provocation in allergic rhinitis.

Raap U, Fokkens W, Bruder M, Hoogsteden H, Kapp A, Braunstahl GJ
Allergy 2008 Apr;63(4):468-75

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IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells.

Gleissner CA, Zastrow A, Klingenberg R, Kluger MS, Konstandin M, Celik S, Haemmerling S, Shankar V, Giese T, Katus HA, Dengler TJ
European journal of immunology 2007 Jan;37(1):177-92