Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS5855 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PHKG1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 293-338 of Human PHKG1.
- Description
- PHKG1 (phosphorylase kinase subunit ÎÛ1), is a subunit of phosphorylase kinase (PHK) that belongs to the Ser/Thr protein kinase family. PHK is a hexadecameric protein composed of four Ï« chains, four ÉÇ chains, four ÎÛ chains and four Ñ´ chains. The ÎÛ chains are catalytic chains, the Ï« and ÉÇ chains are regulatory chains and the Ñ´ chains are calmodulins. PHKG1 contains two calmodulin-binding domains and one protein kinase domain. As the catalytic chain of PHK, PHKG1 is responsible for catalyzing the phosphorylation and activation of glycogen phosphorylase and therefore it plays an important role in the glycogenolytic pathway. Mutations in the gene encoding PHKG1 can lead to PHK deficiency and result in glycogen storage disease type 9C (GSD9C), also known as autosomal liver glycogenosis.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of PHKG1 pAb at 1:500 dilutionLane1:A549 cell lysateLane2:Raw264.7 cell lysateLane3:Rat brain tissue lysate