Antibody data

Product number
BS5855 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PHKG1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 293-338 of Human PHKG1.
Description
PHKG1 (phosphorylase kinase subunit ÎÛ1), is a subunit of phosphorylase kinase (PHK) that belongs to the Ser/Thr protein kinase family. PHK is a hexadecameric protein composed of four Ï« chains, four ÉÇ chains, four ÎÛ chains and four Ñ´ chains. The ÎÛ chains are catalytic chains, the Ï« and ÉÇ chains are regulatory chains and the Ñ´ chains are calmodulins. PHKG1 contains two calmodulin-binding domains and one protein kinase domain. As the catalytic chain of PHK, PHKG1 is responsible for catalyzing the phosphorylation and activation of glycogen phosphorylase and therefore it plays an important role in the glycogenolytic pathway. Mutations in the gene encoding PHKG1 can lead to PHK deficiency and result in glycogen storage disease type 9C (GSD9C), also known as autosomal liver glycogenosis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PHKG1 protein structure - BS5855 shown in red.