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- References [5]
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- Product number
- H00009943-M09 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00009943-M09, RRID:AB_546700
- Product name
- Mouse Monoclonal OXSR1 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. OXSR1 - oxidative-stress responsive 1
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension.
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression.
WNK-OSR1/SPAK-NCC signal cascade has circadian rhythm dependent on aldosterone.
Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.
Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade.
Wakabayashi M, Mori T, Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Matsuo H, Murata T, Nomura S, Asano T, Kawaguchi H, Nonoyama S, Rai T, Sasaki S, Uchida S
Cell reports 2013 Mar 28;3(3):858-68
Cell reports 2013 Mar 28;3(3):858-68
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression.
Trudu M, Janas S, Lanzani C, Debaix H, Schaeffer C, Ikehata M, Citterio L, Demaretz S, Trevisani F, Ristagno G, Glaudemans B, Laghmani K, Dell'Antonio G, SKIPOGH team, Loffing J, Rastaldi MP, Manunta P, Devuyst O, Rampoldi L
Nature medicine 2013 Dec;19(12):1655-60
Nature medicine 2013 Dec;19(12):1655-60
WNK-OSR1/SPAK-NCC signal cascade has circadian rhythm dependent on aldosterone.
Susa K, Sohara E, Isobe K, Chiga M, Rai T, Sasaki S, Uchida S
Biochemical and biophysical research communications 2012 Nov 2;427(4):743-7
Biochemical and biophysical research communications 2012 Nov 2;427(4):743-7
Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.
Susa K, Kita S, Iwamoto T, Yang SS, Lin SH, Ohta A, Sohara E, Rai T, Sasaki S, Alessi DR, Uchida S
Clinical and experimental nephrology 2012 Aug;16(4):530-8
Clinical and experimental nephrology 2012 Aug;16(4):530-8
Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade.
Chiga M, Rafiqi FH, Alessi DR, Sohara E, Ohta A, Rai T, Sasaki S, Uchida S
Journal of cell science 2011 May 1;124(Pt 9):1391-5
Journal of cell science 2011 May 1;124(Pt 9):1391-5
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: OXSR1 Antibody (5D5) [H00009943-M09] - Analysis of OXSR1 expression in HeLa (Cat # L013V1).
