Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 15395-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15395-1-AP, RRID:AB_2237723
- Product name
- PRMT6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PRMT6 antibody (Cat. #15395-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of protein arginine methyltransferase 6 activates interferon signaling and induces the apoptosis of endometrial cancer cells via histone modification.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction.
F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis.
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
Generation of PRMT6 homozygous knockout human embryonic stem cell lines.
Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling.
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis.
PRMT6 mediates CSE induced inflammation and apoptosis.
Inoue F, Sone K, Kumegawa K, Hachijo R, Suzuki E, Tanimoto S, Tsuboyama N, Kato K, Toyohara Y, Takahashi Y, Kusakabe M, Kukita A, Honjoh H, Nishijima A, Taguchi A, Miyamoto Y, Tanikawa M, Iriyama T, Mori M, Wada-Hiraike O, Oda K, Suzuki H, Maruyama R, Osuga Y
International journal of oncology 2024 Mar;64(3)
International journal of oncology 2024 Mar;64(3)
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Prakasam R, Bonadiman A, Andreotti R, Zuccaro E, Dalfovo D, Marchioretti C, Tripathy D, Petris G, Anderson EN, Migazzi A, Tosatto L, Cereseto A, Battaglioli E, Sorarù G, Lim WF, Rinaldi C, Sambataro F, Pourshafie N, Grunseich C, Romanel A, Pandey UB, Contestabile A, Ronzitti G, Basso M, Pennuto M
Nature communications 2023 Feb 6;14(1):603
Nature communications 2023 Feb 6;14(1):603
Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction.
Rome FI, Hughey CC
Molecular metabolism 2022 Apr;58:101452
Molecular metabolism 2022 Apr;58:101452
F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis.
Li T, He X, Luo L, Zeng H, Ren S, Chen Y
Frontiers in cell and developmental biology 2021;9:599020
Frontiers in cell and developmental biology 2021;9:599020
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
Migazzi A, Scaramuzzino C, Anderson EN, Tripathy D, Hernández IH, Grant RA, Roccuzzo M, Tosatto L, Virlogeux A, Zuccato C, Caricasole A, Ratovitski T, Ross CA, Pandey UB, Lucas JJ, Saudou F, Pennuto M, Basso M
Cell reports 2021 Apr 13;35(2):108980
Cell reports 2021 Apr 13;35(2):108980
Generation of PRMT6 homozygous knockout human embryonic stem cell lines.
Li T, Jin W, He Y, Zhou Z
Stem cell research 2020 Dec 28;50:102136
Stem cell research 2020 Dec 28;50:102136
Cigarette smoke extract induces airway epithelial cell death via repressing PRMT6/AKT signaling.
Li T, Fanning KV, Nyunoya T, Chen Y, Zou C
Aging 2020 Dec 1;12(23):24301-24317
Aging 2020 Dec 1;12(23):24301-24317
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Feng Q, Li X, Sun W, Sun M, Li Z, Sheng H, Xie F, Zhang S, Shan C
Biochemical pharmacology 2020 Aug;178:114092
Biochemical pharmacology 2020 Aug;178:114092
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR 3rd, Jones KA
PLoS pathogens 2018 May;14(5):e1007071
PLoS pathogens 2018 May;14(5):e1007071
Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis.
Yan WW, Liang YL, Zhang QX, Wang D, Lei MZ, Qu J, He XH, Lei QY, Wang YP
EMBO reports 2018 Dec;19(12)
EMBO reports 2018 Dec;19(12)
PRMT6 mediates CSE induced inflammation and apoptosis.
Kang N, Chen P, Chen Y, Zeng H, He X, Zhu Y
International immunopharmacology 2015 Jan;24(1):95-101
International immunopharmacology 2015 Jan;24(1):95-101
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 15395-1-AP(PRMT6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15395-1-AP(PRMT6 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRMT6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PRMT6. This antibody recognizes human antigen. The PRMT6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
