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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [18]
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- Validations
- Western blot [2]
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- Product number
- NB100-56642 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56642, RRID:AB_838734
- Product name
- Rabbit Polyclonal PRMT6 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.2 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling.
PRMT4 is involved in insulin secretion via the methylation of histone H3 in pancreatic β cells.
A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator.
Activity-based protein profiling of protein arginine methyltransferase 1.
Regulation of post-translational protein arginine methylation during HeLa cell cycle.
Proteomic identification and comparative analysis of asymmetrically arginine-methylated proteins in immortalized, young and senescent cells.
Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family.
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation.
Down-regulation of asymmetric arginine methylation during replicative and H2O2-induced premature senescence in WI-38 human diploid fibroblasts.
Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior.
Functional role and species-specific contribution of arginases in pulmonary fibrosis.
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.
Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA.
Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat Interactions with both cyclin T1 and the Tat transactivation region.
Dynamics of human protein arginine methyltransferase 1(PRMT1) in vivo.
Multimerization of expressed protein-arginine methyltransferases during the growth and differentiation of rat liver.
Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression.
Arginine methylation of scaffold attachment factor A by heterogeneous nuclear ribonucleoprotein particle-associated PRMT1.
Zhang H, Han C, Li T, Li N, Cao X
Cellular & molecular immunology 2019 Oct;16(10):800-809
Cellular & molecular immunology 2019 Oct;16(10):800-809
PRMT4 is involved in insulin secretion via the methylation of histone H3 in pancreatic β cells.
Kim JK, Lim Y, Lee JO, Lee YS, Won NH, Kim H, Kim HS
Journal of molecular endocrinology 2015 Jun;54(3):315-24
Journal of molecular endocrinology 2015 Jun;54(3):315-24
A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator.
Di Lorenzo A, Yang Y, Macaluso M, Bedford MT
Nucleic acids research 2014 Jul;42(13):8297-309
Nucleic acids research 2014 Jul;42(13):8297-309
Activity-based protein profiling of protein arginine methyltransferase 1.
Obianyo O, Causey CP, Jones JE, Thompson PR
ACS chemical biology 2011 Oct 21;6(10):1127-35
ACS chemical biology 2011 Oct 21;6(10):1127-35
Regulation of post-translational protein arginine methylation during HeLa cell cycle.
Kim C, Lim Y, Yoo BC, Won NH, Kim S, Kim G
Biochimica et biophysica acta 2010 Sep;1800(9):977-85
Biochimica et biophysica acta 2010 Sep;1800(9):977-85
Proteomic identification and comparative analysis of asymmetrically arginine-methylated proteins in immortalized, young and senescent cells.
Lim Y, Hong E, Kwon D, Lee E
Electrophoresis 2010 Dec;31(23-24):3823-33
Electrophoresis 2010 Dec;31(23-24):3823-33
Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family.
Herrmann F, Pably P, Eckerich C, Bedford MT, Fackelmayer FO
Journal of cell science 2009 Mar 1;122(Pt 5):667-77
Journal of cell science 2009 Mar 1;122(Pt 5):667-77
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation.
Yu Z, Chen T, Hébert J, Li E, Richard S
Molecular and cellular biology 2009 Jun;29(11):2982-96
Molecular and cellular biology 2009 Jun;29(11):2982-96
Down-regulation of asymmetric arginine methylation during replicative and H2O2-induced premature senescence in WI-38 human diploid fibroblasts.
Lim Y, Lee E, Lee J, Oh S, Kim S
Journal of biochemistry 2008 Oct;144(4):523-9
Journal of biochemistry 2008 Oct;144(4):523-9
Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior.
Fronz K, Otto S, Kölbel K, Kühn U, Friedrich H, Schierhorn A, Beck-Sickinger AG, Ostareck-Lederer A, Wahle E
The Journal of biological chemistry 2008 Jul 18;283(29):20408-20
The Journal of biological chemistry 2008 Jul 18;283(29):20408-20
Functional role and species-specific contribution of arginases in pulmonary fibrosis.
Kitowska K, Zakrzewicz D, Königshoff M, Chrobak I, Grimminger F, Seeger W, Bulau P, Eickelberg O
American journal of physiology. Lung cellular and molecular physiology 2008 Jan;294(1):L34-45
American journal of physiology. Lung cellular and molecular physiology 2008 Jan;294(1):L34-45
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.
Guccione E, Bassi C, Casadio F, Martinato F, Cesaroni M, Schuchlautz H, Lüscher B, Amati B
Nature 2007 Oct 18;449(7164):933-7
Nature 2007 Oct 18;449(7164):933-7
Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA.
Bulau P, Zakrzewicz D, Kitowska K, Leiper J, Gunther A, Grimminger F, Eickelberg O
American journal of physiology. Lung cellular and molecular physiology 2007 Jan;292(1):L18-24
American journal of physiology. Lung cellular and molecular physiology 2007 Jan;292(1):L18-24
Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat Interactions with both cyclin T1 and the Tat transactivation region.
Xie B, Invernizzi CF, Richard S, Wainberg MA
Journal of virology 2007 Apr;81(8):4226-34
Journal of virology 2007 Apr;81(8):4226-34
Dynamics of human protein arginine methyltransferase 1(PRMT1) in vivo.
Herrmann F, Lee J, Bedford MT, Fackelmayer FO
The Journal of biological chemistry 2005 Nov 11;280(45):38005-10
The Journal of biological chemistry 2005 Nov 11;280(45):38005-10
Multimerization of expressed protein-arginine methyltransferases during the growth and differentiation of rat liver.
Lim Y, Kwon YH, Won NH, Min BH, Park IS, Paik WK, Kim S
Biochimica et biophysica acta 2005 May 25;1723(1-3):240-7
Biochimica et biophysica acta 2005 May 25;1723(1-3):240-7
Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression.
Boulanger MC, Liang C, Russell RS, Lin R, Bedford MT, Wainberg MA, Richard S
Journal of virology 2005 Jan;79(1):124-31
Journal of virology 2005 Jan;79(1):124-31
Arginine methylation of scaffold attachment factor A by heterogeneous nuclear ribonucleoprotein particle-associated PRMT1.
Herrmann F, Bossert M, Schwander A, Akgün E, Fackelmayer FO
The Journal of biological chemistry 2004 Nov 19;279(47):48774-9
The Journal of biological chemistry 2004 Nov 19;279(47):48774-9
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PRMT6 Antibody [NB100-56642] - Analysis of PRMT6 in HeLa lysate using PRMT6 antibody at 1:500 dilution.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PRMT6 Antibody [NB100-56642] - Mouse 4T1 cells and EMT6 cells whole cell lysate. Image from verified customer review.
