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- Antibody Data
- Antigen structure
- References [16]
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- Western blot [1]
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- Product number
- 21646-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PRKG1 antibody
- Antibody type
- Polyclonal
- Description
- PRKG1 antibody (Cat. #21646-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references EDNRB inhibits the growth and migration of prostate cancer cells by activating the cGMP-PKG pathway.
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Specific dilation pattern in placental circulation and the NO/sGC role in preeclampsia placental vessels.
Cucurbitacin C suppresses the progression of pancreatic ductal adenocarcinoma via inhibition of the cGMP-PKG-VASP axis.
Zhenwu decoction ameliorates cardiac hypertrophy through activating sGC (soluble guanylate cyclase) - cGMP (cyclic guanosine monophosphate) - PKG (protein kinase G) pathway.
Potential cardiotoxicity induced by Euodiae Fructus: In vivo and in vitro experiments and untargeted metabolomics research.
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart.
Emodin Interferes With Nitroglycerin-Induced Migraine in Rats Through CGMP-PKG Pathway.
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
NEK7 promotes gastric cancer progression as a cell proliferation regulator.
Upregulation of Connexin 40 Mediated by Nitric Oxide Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage via the Nitric Oxide-Cyclic Guanosine Monophosphate-Protein Kinase G Pathway.
Fluoride-induced unrestored arrest during haploid period of spermatogenesis via the regulation of DDX25 in rats.
Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline.
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Li X, Liu B, Wang S, Dong Q, Li J
Open medicine (Warsaw, Poland) 2024;19(1):20230875
Open medicine (Warsaw, Poland) 2024;19(1):20230875
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Gao S, Yao W, Zhou R, Pei Z
iScience 2024 Apr 19;27(4):109351
iScience 2024 Apr 19;27(4):109351
Specific dilation pattern in placental circulation and the NO/sGC role in preeclampsia placental vessels.
Tang J, Zhang Y, Zhang Z, Tao J, Wu J, Zheng Q, Xu T, Li N, Xu Z
Frontiers in endocrinology 2023;14:1182636
Frontiers in endocrinology 2023;14:1182636
Cucurbitacin C suppresses the progression of pancreatic ductal adenocarcinoma via inhibition of the cGMP-PKG-VASP axis.
Xu D, Liu A, Liu Q, Zhang H, Tian M, Bian Y, Zhang X, Ying M, Shen H
Biochemical pharmacology 2023 Nov;217:115810
Biochemical pharmacology 2023 Nov;217:115810
Zhenwu decoction ameliorates cardiac hypertrophy through activating sGC (soluble guanylate cyclase) - cGMP (cyclic guanosine monophosphate) - PKG (protein kinase G) pathway.
Chen L, Zhou X, Deng Y, Yang Y, Chen X, Chen Q, Liu Y, Fu X, Kwan HY, You Y, Jin W, Zhao X
Journal of ethnopharmacology 2023 Jan 10;300:115705
Journal of ethnopharmacology 2023 Jan 10;300:115705
Potential cardiotoxicity induced by Euodiae Fructus: In vivo and in vitro experiments and untargeted metabolomics research.
Zhang D, Lü J, Ren Z, Zhang X, Wu H, Sa R, Wang X, Wang Y, Lin Z, Zhang B
Frontiers in pharmacology 2022;13:1028046
Frontiers in pharmacology 2022;13:1028046
A novel phosphodiesterase 9A inhibitor LW33 protects against ischemic stroke through the cGMP/PKG/CREB pathway.
You JY, Liu XW, Bao YX, Shen ZN, Wang Q, He GY, Lu J, Zhang JG, Chen JW, Liu PQ
European journal of pharmacology 2022 Jun 15;925:174987
European journal of pharmacology 2022 Jun 15;925:174987
Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart.
Gu M, Zhou X, Zhu L, Gao Y, Gao L, Bai C, Yang L, Li G
Frontiers in cell and developmental biology 2021;9:774185
Frontiers in cell and developmental biology 2021;9:774185
Emodin Interferes With Nitroglycerin-Induced Migraine in Rats Through CGMP-PKG Pathway.
Sun S, Zheng G, Zhou D, Zhu L, He X, Zhang C, Wang C, Yuan C
Frontiers in pharmacology 2021;12:758026
Frontiers in pharmacology 2021;12:758026
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
Chen J, Ren W, Lin L, Zeng S, Huang L, Tang J, Bi S, Pan J, Chen D, Du L
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
NEK7 promotes gastric cancer progression as a cell proliferation regulator.
Li YK, Zhu XR, Zhan Y, Yuan WZ, Jin WL
Cancer cell international 2021 Aug 21;21(1):438
Cancer cell international 2021 Aug 21;21(1):438
Upregulation of Connexin 40 Mediated by Nitric Oxide Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage via the Nitric Oxide-Cyclic Guanosine Monophosphate-Protein Kinase G Pathway.
Lan SH, Lai WT, Zheng SY, Yang L, Fang LC, Zhou L, Tang B, Duan J, Hong T
World neurosurgery 2020 Apr;136:e476-e486
World neurosurgery 2020 Apr;136:e476-e486
Fluoride-induced unrestored arrest during haploid period of spermatogenesis via the regulation of DDX25 in rats.
Han Y, Yu Y, Liang C, Shi Y, Zhu Y, Zheng H, Wang J, Zhang J
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:538-551
Environmental pollution (Barking, Essex : 1987) 2019 Oct;253:538-551
Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline.
Sun Z, Liu Y, Yu F, Xu Y, Yanli L, Liu N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108933
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108933
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, Liu X, Xu L, Li X, Yu X, Sun B, Chen L
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Zhu E, Yang Y, Zhang J, Li Y, Li C, Chen L, Sun B
Oncotarget 2016 Dec 6;7(49):81077-81089
Oncotarget 2016 Dec 6;7(49):81077-81089
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRKG1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PRKG1. This antibody recognizes human antigen. The PRKG1 antibody has been validated for the following applications: ELISA, WB analysis.
