ABIN185309
antibody from antibodies-online
Targeting: LRRK2
DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN185309 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN185309, RRID:AB_10780441
- Product name
- anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term), (Internal Region) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide with sequence CELAEKMRRTSV, from the internal region (near the C Terminus) of the protein sequence according to NP_940980.3.
- Description
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Reactivity
- Human
- Host
- Goat
- Epitope
- C-Term,Internal Region
- Vial size
- 100 μg
- Storage
- Aliquot and store at -20°C.
- Handling
- Minimize freezing and thawing.
Submitted references LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study.
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model.
LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease.
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease.
Sharma S, Bandopadhyay R, Lashley T, Renton AE, Kingsbury AE, Kumaran R, Kallis C, Vilariño-Güell C, O'Sullivan SS, Lees AJ, Revesz T, Wood NW, Holton JL
Neuropathology and applied neurobiology 2011 Dec;37(7):777-90
Neuropathology and applied neurobiology 2011 Dec;37(7):777-90
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model.
Alegre-Abarrategui J, Christian H, Lufino MM, Mutihac R, Venda LL, Ansorge O, Wade-Martins R
Human molecular genetics 2009 Nov 1;18(21):4022-34
Human molecular genetics 2009 Nov 1;18(21):4022-34
LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease.
Alegre-Abarrategui J, Ansorge O, Esiri M, Wade-Martins R
Neuropathology and applied neurobiology 2008 Jun;34(3):272-83
Neuropathology and applied neurobiology 2008 Jun;34(3):272-83
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease.
Paisán-Ruíz C, Jain S, Evans EW, Gilks WP, Simón J, van der Brug M, López de Munain A, Aparicio S, Gil AM, Khan N, Johnson J, Martinez JR, Nicholl D, Carrera IM, Pena AS, de Silva R, Lees A, Martí-Massó JF, Pérez-Tur J, Wood NW, Singleton AB
Neuron 2004 Nov 18;44(4):595-600
Neuron 2004 Nov 18;44(4):595-600
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