ABIN387804

antibody from antibodies-online

Targeting: LRRK2 DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN387804

Provider

antibodies-online

Product name

anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibody

Antibody type

Monoclonal

Antigen

This PARK8 (LRRK2) antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.

Description

This antibody is purified through a protein G column, followed by dialysis against PBS.

Reactivity

Human, Mouse

Host

Mouse

Epitope

C-Term

Isotype

IgG

Antibody clone number

133AT1218

Vial size

400 μL

Concentration

1.5 mg/mL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

Absence of commonly reported leucine-rich repeat kinase 2 mutations in Eastern Indian Parkinson's disease patients.

Sanyal J, Sarkar B, Ojha S, Banerjee TK, Ray BC, Rao VR
Genetic testing and molecular biomarkers 2010 Oct;14(5):691-4

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Penetrance in Parkinson's disease related to the LRRK2 R1441G mutation in the Basque country (Spain).

Ruiz-Martínez J, Gorostidi A, Ibañez B, Alzualde A, Otaegui D, Moreno F, López de Munain A, Bergareche A, Gómez-Esteban JC, Martí Massó JF
Movement disorders : official journal of the Movement Disorder Society 2010 Oct 30;25(14):2340-5

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Low frequency of common LRRK2 mutations in Mexican patients with Parkinson's disease.

Yescas P, López M, Monroy N, Boll MC, Rodríguez-Violante M, Rodríguez U, Ochoa A, Alonso ME
Neuroscience letters 2010 Nov 19;485(2):79-82

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LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease.

Saunders-Pullman R, Barrett MJ, Stanley KM, Luciano MS, Shanker V, Severt L, Hunt A, Raymond D, Ozelius LJ, Bressman SB
Movement disorders : official journal of the Movement Disorder Society 2010 Nov 15;25(15):2536-41

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Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells.

Ortiz-Ortiz MA, Morán JM, Ruiz-Mesa LM, Niso-Santano M, Bravo-SanPedro JM, Gómez-Sánchez R, González-Polo RA, Fuentes JM
Neuroscience letters 2010 Jan 4;468(2):120-4

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Olfactory heterogeneity in LRRK2 related Parkinsonism.

Silveira-Moriyama L, Munhoz RP, de J Carvalho M, Raskin S, Rogaeva E, de C Aguiar P, Bressan RA, Felicio AC, Barsottini OG, Andrade LA, Chien HF, Bonifati V, Barbosa ER, Teive HA, Lees AJ
Movement disorders : official journal of the Movement Disorder Society 2010 Dec 15;25(16):2879-83

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Dynamic and redundant regulation of LRRK2 and LRRK1 expression.

Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB
BMC neuroscience 2007 Nov 28;8:102