ALX-210-928-C100
antibody from Enzo Life Sciences
Targeting: LRRK2
DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunocytochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ALX-210-928-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-210-928-C100, RRID:AB_2051807
- Product name
- LRRK2 (human) polyclonal antibody (AT106)
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Protein A-affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20¡C.
Submitted references LRRK2 in Parkinson's disease and dementia with Lewy bodies.
Zhu X, Babar A, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Perry G, Chen SG
Molecular neurodegeneration 2006 Nov 30;1:17
Molecular neurodegeneration 2006 Nov 30;1:17
No comments: Submit comment
Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Detection of human LRRK2 by PAb to LRRK2 (human) (AT106) (Prod. No. ALX-210-928). Method: Cell extracts of HEK 293T transfected with an expression vector encoding either for Flag¨-tagged human LRRK2 (lane 1) or Flag¨-tagged human LRRK2_N (lane 2) were run on a SDS-PAGE gel and analyzed by Western blot. After transfer, the nitrocellulose membrane was probed with PAb to LRRK2 at 1:1'000 for 1 hour at room temperature and then incubated with a goat anti-rabbit horseradish peroxidase (dilution at 1:4'000).ÊÊ
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemical staining of pyramidal neurons using PAb to LRRK2 (AT106) (Prod. No. ALX-210-928). Method: PAb to LRRK2 was used at a dilution of 1:500 in paraformaldehyde fixed tissue of a case of diffuse Lewy body disease.