Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS1916 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Histone H1.0 (R94) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 61-110 of Human Histone H1.0.
- Description
- Histone H1.0 (H1 histone family, member 0) is a lysine rich member of the H1 family of linker histones. The H1 family of proteins interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histone H10 is a unique variant considered a replacement linker histone which is expressed and incorporated into chromatin in the absence of DNA replication. In contrast, the majority of somatic H1 histones are replication dependent variants found in proliferating cells. Histone H1.0 is expressed in cells that are in the terminal stages of differentiation or that have low rates of cell division. Unlike other differentiation-specific linker histones which demonstrate tissue and species-specific expression, Histone H1.0 is widely expressed in many tissues in most vertebrates.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of Histone H1.0 (R94) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Mouse brain tissue lysateLane3:Rat brain tissue lysate