Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 17510-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17510-1-AP, RRID:AB_10695628
- Product name
- Histone H1.0 antibody
- Antibody type
- Polyclonal
- Description
- Histone H1.0 antibody (Cat. #17510-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Nonstructural Protein 1 Mediates HMGB1 Release by Targeting Histone H1.0 After Respiratory Syncytial Virus Infection In Vivo and In Vitro.
The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.
CRAMP1 drives linker histone expression to enable Polycomb repression.
CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance.
Histone H1.0 couples cellular mechanical behaviors to chromatin structure.
The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.
Inhibition of ubiquitin-specific protease 7 ameliorates ferroptosis-mediated myocardial infarction by contrasting oxidative stress: An in vitro and in vivo analysis.
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage.
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
GATA4 Regulates Inflammation-Driven Pancreatic Ductal Adenocarcinoma Progression.
Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells.
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.
PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.
ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.
Inflammatory stimuli promote growth and invasion of pancreatic cancer cells through NF-κB pathway dependent repression of PP2Ac.
Pin1 promotes GR transactivation by enhancing recruitment to target genes.
Zhou N, Che S, Zhai H, Xie X, Liu E, Xie J
Inflammation 2025 Oct;48(5):3579-3591
Inflammation 2025 Oct;48(5):3579-3591
The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.
Song W, Zhao Y, Ruggiano A, Redfield C, Newman JA, Zhu X, García-Flores M, Cruz-Migoni A, Roddan R, Pérez-Ràfols A, McHugh PJ, Elliott PR, Ramadan K
Nucleic acids research 2025 Jul 8;53(13)
Nucleic acids research 2025 Jul 8;53(13)
CRAMP1 drives linker histone expression to enable Polycomb repression.
Matthews RE, Danac JMC, Naden EL, Farleigh Smith LE, Lestari S, Gungi A, Appert A, Buttress T, Verma A, Sinclair O, Chong F, Suberu J, Antrobus R, Bonev B, Dawson MA, Reid AJ, Timms RT, Ahringer J, Tchasovnikarova IA
Molecular cell 2025 Jul 3;85(13):2503-2516.e8
Molecular cell 2025 Jul 3;85(13):2503-2516.e8
CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance.
Ingham A, de Vega IA, Morlot L, Gittens W, Hendriks IA, Kakulidis ES, Freire R, Davey NE, Duxin JP, Lund Nielsen M, Mailand N
Molecular cell 2025 Jul 3;85(13):2487-2502.e12
Molecular cell 2025 Jul 3;85(13):2487-2502.e12
Histone H1.0 couples cellular mechanical behaviors to chromatin structure.
Hu S, Chapski DJ, Gehred ND, Kimball TH, Gromova T, Flores A, Rowat AC, Chen J, Packard RRS, Olszewski E, Davis J, Rau CD, McKinsey TA, Rosa-Garrido M, Vondriska TM
Nature cardiovascular research 2024;3(4):441-459
Nature cardiovascular research 2024;3(4):441-459
The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks.
Song W, Zhao Y, Ruggiano A, Redfield C, Newman JA, Zhu X, Cruz-Migoni A, Roddan R, McHugh P, Elliott P, Ramadan K
bioRxiv : the preprint server for biology 2024 Nov 26;
bioRxiv : the preprint server for biology 2024 Nov 26;
Inhibition of ubiquitin-specific protease 7 ameliorates ferroptosis-mediated myocardial infarction by contrasting oxidative stress: An in vitro and in vivo analysis.
Yang D, Zhang T, Qu H, Li S, Lu J, Cao W, Chen Z, Zhang H, Yang J, Wang J
Cellular signalling 2024 Dec;124:111423
Cellular signalling 2024 Dec;124:111423
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage.
Wei Y, Miao Q, Zhang Q, Mao S, Li M, Xu X, Xia X, Wei K, Fan Y, Zheng X, Fang Y, Mei M, Zhang Q, Ding J, Fan Y, Lu M, Hu G
Nature neuroscience 2023 Dec;26(12):2081-2089
Nature neuroscience 2023 Dec;26(12):2081-2089
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Zheng X, Liu Z, Zhong J, Zhou L, Chen J, Zheng L, Li Z, Zhang R, Pan J, Wu Y, Liu Z, Kang T
Oncogene 2022 Jul;41(28):3587-3598
Oncogene 2022 Jul;41(28):3587-3598
GATA4 Regulates Inflammation-Driven Pancreatic Ductal Adenocarcinoma Progression.
Jiang W, Chen C, Huang L, Shen J, Yang L
Frontiers in cell and developmental biology 2021;9:640391
Frontiers in cell and developmental biology 2021;9:640391
Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells.
Kato K, Kawaguchi A, Nagata K
Scientific reports 2021 Sep 6;11(1):17726
Scientific reports 2021 Sep 6;11(1):17726
RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2.
Zhang J, Chen H, Weng X, Liu H, Chen Z, Huang Q, Wang L, Liu X
Cell death discovery 2021 Oct 27;7(1):317
Cell death discovery 2021 Oct 27;7(1):317
Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.
Tian N, Shangguan W, Zhou Z, Yao Y, Fan C, Cai L
Journal of Cancer 2019;10(24):6074-6087
Journal of Cancer 2019;10(24):6074-6087
PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy.
Zeng J, Liu W, Fan YZ, He DL, Li L
Theranostics 2018;8(1):109-123
Theranostics 2018;8(1):109-123
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.
Feng L, Sheng J, Vu GP, Liu Y, Foo C, Wu S, Trang P, Paliza-Carre M, Ran Y, Yang X, Sun X, Deng Z, Zhou T, Lu S, Li H, Liu F
PLoS pathogens 2018 Jan;14(1):e1006867
PLoS pathogens 2018 Jan;14(1):e1006867
ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs.
Ren K, Lu YJ, Mo ZC, -Liu X, Tang ZL, Jiang Y, Peng XS, Li L, Zhang QH, Yi GH
Journal of physiology and biochemistry 2017 May;73(2):287-296
Journal of physiology and biochemistry 2017 May;73(2):287-296
Inflammatory stimuli promote growth and invasion of pancreatic cancer cells through NF-κB pathway dependent repression of PP2Ac.
Tao M, Liu L, Shen M, Zhi Q, Gong FR, Zhou BP, Wu Y, Liu H, Chen K, Shen B, Wu MY, Shou LM, Li W
Cell cycle (Georgetown, Tex.) 2016;15(3):381-93
Cell cycle (Georgetown, Tex.) 2016;15(3):381-93
Pin1 promotes GR transactivation by enhancing recruitment to target genes.
Poolman TM, Farrow SN, Matthews L, Loudon AS, Ray DW
Nucleic acids research 2013 Oct;41(18):8515-25
Nucleic acids research 2013 Oct;41(18):8515-25
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 17510-1-AP(H1F0 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The Histone H1.0 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Histone H1.0. This antibody recognizes human,mouse,rat antigen. The Histone H1.0 antibody has been validated for the following applications: ELISA, WB, IF analysis.