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- Antibody Data
- Antigen structure
- References [22]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 21555-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21555-1-AP, RRID:AB_10733471
- Product name
- CYP26B1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CYP26B1 antibody (Cat. #21555-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Serine Glycine Restriction Aggravates Hepatic Ischemia-reperfusion Injury.
Multi-omic analysis reveals retinoic acid molecular drivers for dermal fibrosis and regenerative repair in the skin.
Sulfur Dioxide Alleviates Aortic Dissection Through Inhibiting Vascular Smooth Muscle Cell Phenotype Switch, Migration, and Proliferation via miR-184-3p/Cyp26b1 Axis.
Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival.
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation.
Retinoic acid-mediated homeostatic plasticity in the nucleus accumbens core contributes to incubation of cocaine craving.
m(1)A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma.
Wnt/β-Catenin Promotes the Osteoblastic Potential of BMP9 Through Down-Regulating Cyp26b1 in Mesenchymal Stem Cells.
All-Trans Retinoic Acid Prevents the Progression of Gastric Precancerous Lesions by Regulating Disordered Retinoic Acid Metabolism.
All-trans Retinoic Acid has Limited Therapeutic Effects on Cognition and Hippocampal Protein Expression After Controlled Cortical Impact.
Effects of high-dose all-trans retinoic acid on longitudinal bone growth of young rats.
Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment.
Dysregulated retinoic acid signaling in airway smooth muscle cells in asthma.
Decay in Retinoic Acid Signaling in Varied Models of Alzheimer's Disease and In-Vitro Test of Novel Retinoic Acid Receptor Ligands (RAR-Ms) to Regulate Protective Genes.
Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.
CYP26B1 declines postnatally in Sertoli cells independently of androgen action in the mouse testis.
Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma.
Transcriptomics of Environmental Enrichment Reveals a Role for Retinoic Acid Signaling in Addiction.
De Novo-Synthesized Retinoic Acid in Ovarian Antral Follicles Enhances FSH-Mediated Ovarian Follicular Cell Differentiation and Female Fertility.
The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map.
Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.
Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo.
Yang M, Wang J, Li C, Yang Z, Dong W, Zhang C, Jin J
Transplantation 2026 Jan 1;110(1):e103-e115
Transplantation 2026 Jan 1;110(1):e103-e115
Multi-omic analysis reveals retinoic acid molecular drivers for dermal fibrosis and regenerative repair in the skin.
Griffin M, Guo JL, Parker JBL, Kuhnert M, Li DJ, Valencia C, Morgan A, Downer M, Cotterell AC, Lu JM, Dilorio S, Bauer-Rowe Ramos KE, Januszyk M, Chang HY, Wan DC, Longaker MT
Cell stem cell 2025 Sep 4;32(9):1421-1437.e6
Cell stem cell 2025 Sep 4;32(9):1421-1437.e6
Sulfur Dioxide Alleviates Aortic Dissection Through Inhibiting Vascular Smooth Muscle Cell Phenotype Switch, Migration, and Proliferation via miR-184-3p/Cyp26b1 Axis.
He J, Huang K, Fan X, Chang G
Antioxidants & redox signaling 2025 May;42(13-15):672-686
Antioxidants & redox signaling 2025 May;42(13-15):672-686
Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival.
Irmer B, Wlochowitz D, Krekeler C, Richter KM, Chandrabalan S, Bayerlova M, Wolff A, Lenz G, Conradi LC, Schildhaus HU, Stadelmann C, Rohde V, Proescholdt M, Salinas G, Homayounfar K, Kuhlmann T, Hailfinger S, Pukrop T, Menck K, Beissbarth T, Bleckmann A
Molecular oncology 2025 Mar;19(3):614-634
Molecular oncology 2025 Mar;19(3):614-634
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation.
Xie CT, Zhang HL, Li Y, Li Q, Wen YX, Liu JY, Han F
Cell death & disease 2025 Feb 19;16(1):110
Cell death & disease 2025 Feb 19;16(1):110
Retinoic acid-mediated homeostatic plasticity in the nucleus accumbens core contributes to incubation of cocaine craving.
Wunsch AM, Hwang EK, Funke JR, Baker R, Moutier A, Milovanovic M, Green TA, Wolf ME
Psychopharmacology 2024 Oct;241(10):1983-2001
Psychopharmacology 2024 Oct;241(10):1983-2001
m(1)A regulator-mediated methylation modification patterns correlated with autophagy to predict the prognosis of hepatocellular carcinoma.
Wu Y, Li L, Wang L, Zhang S, Zeng Z, Lu J, Wang Z, Zhang Y, Zhang S, Li H, Chen T
BMC cancer 2024 Apr 22;24(1):506
BMC cancer 2024 Apr 22;24(1):506
Wnt/β-Catenin Promotes the Osteoblastic Potential of BMP9 Through Down-Regulating Cyp26b1 in Mesenchymal Stem Cells.
Yao XT, Li PP, Liu J, Yang YY, Luo ZL, Jiang HT, He WG, Luo HH, Deng YX, He BC
Tissue engineering and regenerative medicine 2023 Aug;20(5):705-723
Tissue engineering and regenerative medicine 2023 Aug;20(5):705-723
All-Trans Retinoic Acid Prevents the Progression of Gastric Precancerous Lesions by Regulating Disordered Retinoic Acid Metabolism.
Wu H, Zhao D, Wang C, Zhang D, Tang M, Qian S, Xu L, Xia T, Zhou J, Wang G, He Y, Gao L, Chen W, Li L, Yang W, Zhao Q, Hu C, Hu A
Nutrition and cancer 2022;74(9):3351-3362
Nutrition and cancer 2022;74(9):3351-3362
All-trans Retinoic Acid has Limited Therapeutic Effects on Cognition and Hippocampal Protein Expression After Controlled Cortical Impact.
Svirsky SE, Ranellone NS, Parry M, Holets E, Henchir J, Li Y, Carlson SW, Dixon CE
Neuroscience 2022 Sep 1;499:130-141
Neuroscience 2022 Sep 1;499:130-141
Effects of high-dose all-trans retinoic acid on longitudinal bone growth of young rats.
Shen Q, Wang X, Bai H, Tan X, Liu X
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2022 Feb;62:101446
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2022 Feb;62:101446
Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment.
Wołoszynowska-Fraser MU, Rossi SL, Long JM, McCaffery PJ, Rapp PR
eNeuro 2021 Sep-Oct;8(5)
eNeuro 2021 Sep-Oct;8(5)
Dysregulated retinoic acid signaling in airway smooth muscle cells in asthma.
Defnet AE, Shah SD, Huang W, Shapiro P, Deshpande DA, Kane MA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22016
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dec;35(12):e22016
Decay in Retinoic Acid Signaling in Varied Models of Alzheimer's Disease and In-Vitro Test of Novel Retinoic Acid Receptor Ligands (RAR-Ms) to Regulate Protective Genes.
Khatib T, Chisholm DR, Whiting A, Platt B, McCaffery P
Journal of Alzheimer's disease : JAD 2020;73(3):935-954
Journal of Alzheimer's disease : JAD 2020;73(3):935-954
Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.
Håglin S, Berghard A, Bohm S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 May 20;40(21):4116-4129
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 May 20;40(21):4116-4129
CYP26B1 declines postnatally in Sertoli cells independently of androgen action in the mouse testis.
Edelsztein NY, Kashimada K, Schteingart HF, Rey RA
Molecular reproduction and development 2020 Jan;87(1):66-77
Molecular reproduction and development 2020 Jan;87(1):66-77
Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma.
Chang J, Zhong R, Tian J, Li J, Zhai K, Ke J, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Zhu Y, Gong Y, Yang Y, Zou D, Peng X, Zhang Z, Zhang X, Huang K, Wu T, Wu C, Miao X, Lin D
Nature genetics 2018 Mar;50(3):338-343
Nature genetics 2018 Mar;50(3):338-343
Transcriptomics of Environmental Enrichment Reveals a Role for Retinoic Acid Signaling in Addiction.
Zhang Y, Kong F, Crofton EJ, Dragosljvich SN, Sinha M, Li D, Fan X, Koshy S, Hommel JD, Spratt HM, Luxon BA, Green TA
Frontiers in molecular neuroscience 2016;9:119
Frontiers in molecular neuroscience 2016;9:119
De Novo-Synthesized Retinoic Acid in Ovarian Antral Follicles Enhances FSH-Mediated Ovarian Follicular Cell Differentiation and Female Fertility.
Kawai T, Yanaka N, Richards JS, Shimada M
Endocrinology 2016 May;157(5):2160-72
Endocrinology 2016 May;157(5):2160-72
The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map.
Login H, Håglin S, Berghard A, Bohm S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Oct 7;35(40):13807-18
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Oct 7;35(40):13807-18
Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.
Login H, Butowt R, Bohm S
Brain structure & function 2015 Jul;220(4):2143-57
Brain structure & function 2015 Jul;220(4):2143-57
Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo.
Bowles J, Secker G, Nguyen C, Kazenwadel J, Truong V, Frampton E, Curtis C, Skoczylas R, Davidson TL, Miura N, Hong YK, Koopman P, Harvey NL, François M
Developmental biology 2014 Feb 1;386(1):25-33
Developmental biology 2014 Feb 1;386(1):25-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 21555-1-AP(CYP26B1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CYP26B1 antibody 21555-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 21555-1-AP(CYP26B1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 21555-1-AP(CYP26B1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
