CABT-BL8370

antibody from Creative Diagnostics

Targeting: TNFRSF12A CD266, FN14, TweakR

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL8370

Provider

Creative Diagnostics

Product name

Anti-TNFRSF12A Monoclonal antibody, clone JUFN-5 [Biotin]

Antibody type

Monoclonal

Description

TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by biding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in aorta and liver. It may also play a role in vascular cell migration and angiogenesis.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Biotin

Isotype

IgG