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Western blot
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 314002 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#314002, RRID:AB_345406
- Product name
- Purified anti-human CD266 (Fn14, TWEAK Receptor)
- Antibody type
- Monoclonal
- Antigen
- Human Fn14 transfected P815
- Description
- TWEAK receptor is also known as fibroblast growth factor inducible 14 kD protein (Fn14) or CD266. It is a 14 kD transmembrane protein that is expressed on a variety of tissue types. This receptor binds TWEAK and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The TWEAK receptor is rapidly induced during liver regeneration and m play a role in hepatocyte growth. TWEAK receptor engagement can induce cell death and may play a role in inflammation. The ITEM-1 antibody is useful for flow cytometric analysis, induction of tumor cells apoptosis or necrotic cell death, enhancing endothelial cell proliferation, and immunohistochemistry on frozen tissues.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C.
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- BioLegend (provider)
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- Experimental details
- Human Fn14 transfected cells stained with purified ITEM-1, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated
