BS8140

antibody from Bioworld Technology, Inc
Targeting: CCAR1 CARP-1, CARP1, FLJ10590
Provider product page for BS8140
Western blot
Immunohistochemistry

Antibody data

Product number
BS8140 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CCAR1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CCAR1.
Description
CARP-1 (cell division cycle and apoptosis regulator 1), also known as CCAR1 or DIS, is a 1,150 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains one SAP domain. Expressed in several epithelial cancer cell lines, including breast, colon, prostate and leukemia, CARP-1 is involved in apoptotic signaling, as well as in cell cycle progression and cell proliferation via interaction with c-Myc and cyclin B1. CARP-1 is subject to DNA damage-induced phosphorylation, probably by ATM or ATR. The gene encoding CARP-1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman£ªs syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CCAR1 protein structure - BS8140 shown in red.