Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA017079 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA017079, RRID:AB_1857467
- Product name
- Anti-SQRDL
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SQRDL, Gene description: sulfide quinone reductase-like (yeast), Alternative Gene Names: CGI-44, Validated applications: ICC, IHC, WB, Uniprot ID: Q9Y6N5, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells
GYY4137-Derived Hydrogen Sulfide Donates Electrons to the Mitochondrial Electron Transport Chain via Sulfide: Quinone Oxidoreductase in Endothelial Cells
Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome
Sequential Accumulation of ‘Driver’ Pathway Mutations Induces the Upregulation of Hydrogen-Sulfide-Producing Enzymes in Human Colonic Epithelial Cell Organoids
N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration
Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia
Santos S, Rodrigues L, Martins V, Petrosino M, Zuhra K, Ascenção K, Anand A, Abdel-Kader R, Gad M, Bourquin C, Szabo C
Antioxidants 2023;12(3):647
Antioxidants 2023;12(3):647
GYY4137-Derived Hydrogen Sulfide Donates Electrons to the Mitochondrial Electron Transport Chain via Sulfide: Quinone Oxidoreductase in Endothelial Cells
Star B, van der Slikke E, Ransy C, Schmitt A, Henning R, Bouillaud F, Bouma H
Antioxidants 2023;12(3):587
Antioxidants 2023;12(3):587
Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome
Panagaki T, Lozano-Montes L, Janickova L, Zuhra K, Szabo M, Majtan T, Rainer G, Maréchal D, Herault Y, Szabo C
Redox Biology 2022;51
Redox Biology 2022;51
Sequential Accumulation of ‘Driver’ Pathway Mutations Induces the Upregulation of Hydrogen-Sulfide-Producing Enzymes in Human Colonic Epithelial Cell Organoids
Ascenção K, Dilek N, Zuhra K, Módis K, Sato T, Szabo C
Antioxidants 2022;11(9):1823
Antioxidants 2022;11(9):1823
N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells
Zuhra K, Tomé C, Masi L, Giardina G, Paulini G, Malagrinò F, Forte E, Vicente J, Giuffrè A
Cells 2019;8(8):828
Cells 2019;8(8):828
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration
Zivanovic J, Kouroussis E, Kohl J, Adhikari B, Bursac B, Schott-Roux S, Petrovic D, Miljkovic J, Thomas-Lopez D, Jung Y, Miler M, Mitchell S, Milosevic V, Gomes J, Benhar M, Gonzalez-Zorn B, Ivanovic-Burmazovic I, Torregrossa R, Mitchell J, Whiteman M, Schwarz G, Snyder S, Paul B, Carroll K, Filipovic M
Cell Metabolism 2019;30(6):1152-1170.e13
Cell Metabolism 2019;30(6):1152-1170.e13
Hydrogen Sulfide Oxidation: Adaptive Changes in Mitochondria of SW480 Colorectal Cancer Cells upon Exposure to Hypoxia
Malagrinò F, Zuhra K, Mascolo L, Mastronicola D, Vicente J, Forte E, Giuffrè A
Oxidative Medicine and Cellular Longevity 2019;2019
Oxidative Medicine and Cellular Longevity 2019;2019
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human colon and placenta tissues using HPA017079 antibody. Corresponding SQRDL RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol