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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- MAB5241 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse GITR/TNFRSF18 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse GITR/TNFRSF18 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) 4-1BB, recombinant mouse (rm) CD27, rmCD30, rmEDAR, rmFas, rhGITR, rhHVEM, rmRANK, rhTROY, and rmTNF R1 is observed.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
O35714- Isotype
- IgG
- Antibody clone number
- 108619
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells.
Protection against autoimmunity in nonlymphopenic hosts by CD4+ CD25+ regulatory T cells is antigen-specific and requires IL-10 and TGF-beta.
Protection against autoimmunity in nonlymphopenic hosts by CD4+ CD25+ regulatory T cells is antigen-specific and requires IL-10 and TGF-beta.
Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression.
Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression.
An essential role for Scurfin in CD4+CD25+ T regulatory cells.
Dobrzynski E, Fitzgerald JC, Cao O, Mingozzi F, Wang L, Herzog RW
Proceedings of the National Academy of Sciences of the United States of America 2006 Mar 21;103(12):4592-7
Proceedings of the National Academy of Sciences of the United States of America 2006 Mar 21;103(12):4592-7
Protection against autoimmunity in nonlymphopenic hosts by CD4+ CD25+ regulatory T cells is antigen-specific and requires IL-10 and TGF-beta.
Huang X, Zhu J, Yang Y
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4283-91
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4283-91
Protection against autoimmunity in nonlymphopenic hosts by CD4+ CD25+ regulatory T cells is antigen-specific and requires IL-10 and TGF-beta.
Huang X, Zhu J, Yang Y
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4283-91
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4283-91
Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression.
Ji HB, Liao G, Faubion WA, Abadía-Molina AC, Cozzo C, Laroux FS, Caton A, Terhorst C
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):5823-7
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):5823-7
Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression.
Ji HB, Liao G, Faubion WA, Abadía-Molina AC, Cozzo C, Laroux FS, Caton A, Terhorst C
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):5823-7
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):5823-7
An essential role for Scurfin in CD4+CD25+ T regulatory cells.
Khattri R, Cox T, Yasayko SA, Ramsdell F
Nature immunology 2003 Apr;4(4):337-42
Nature immunology 2003 Apr;4(4):337-42
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