RA0760

antibody from Oursmab

Targeting: TNFRSF18 AITR, CD357, GITR

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0760

Provider

Oursmab

Product name

Ragifilimab (Biosimilar Reference Antibody) (TNFRSF18)

Antibody type

Monoclonal

Description

Ragifilimab is an agonistic humanized IgG1 kappa monoclonal antibody targeting glucocorticoid-induced TNFR-related protein (GITR, TNFRSF18). By binding and activating GITR, it stimulates T cell effector functions, enhances proliferation, and reduces the suppressive activity of regulatory T cells (Tregs) within the tumor microenvironment. It is being developed as an immunomodulatory therapy for advanced solid tumors, aiming to boost anti-tumor immunity.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Ragifilimab (Biosimilar Reference Antibody) (TNFRSF18)-RA0760-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.