Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Flow cytometry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- FAB1844F-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human KIR2DL1/KIR2DS5 Fluorescein-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human KIR2DL1/KIR2DS5 on transfected cells. It does not stain cells transfected with KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P43626
- Isotype
- IgG
- Antibody clone number
- 143211
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells.
Human Cytomegalovirus Infection Enhances NK Cell Activity In Vitro.
Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles.
The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education.
Tissue-Specific Education of Decidual NK Cells.
2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.
KIR/HLA interactions negatively affect rituximab- but not GA101 (obinutuzumab)-induced antibody-dependent cellular cytotoxicity.
Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients.
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Human immunodeficiency virus type 1 infection is associated with increased NK cell polyfunctionality and higher levels of KIR3DL1+ NK cells in ugandans carrying the HLA-B Bw4 motif.
Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.
Rettman P, Willem C, David G, Riou R, Legrand N, Esbelin J, Cesbron A, Senitzer D, Gagne K, Retière C
Journal of leukocyte biology 2016 Sep;100(3):471-9
Journal of leukocyte biology 2016 Sep;100(3):471-9
Human Cytomegalovirus Infection Enhances NK Cell Activity In Vitro.
Tschan-Plessl A, Stern M, Schmied L, Retière C, Hirsch HH, Garzoni C, van Delden C, Boggian K, Mueller NJ, Berger C, Villard J, Manuel O, Meylan P, Terszowski G
Transplantation direct 2016 Jul;2(7):e89
Transplantation direct 2016 Jul;2(7):e89
Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles.
Pesce S, Carlomagno S, Moretta A, Sivori S, Marcenaro E
Journal of immunology research 2015;2015:754373
Journal of immunology research 2015;2015:754373
The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education.
Marquardt N, Ivarsson MA, Blom K, Gonzalez VD, Braun M, Falconer K, Gustafsson R, Fogdell-Hahn A, Sandberg JK, Michaëlsson J
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 1;195(7):3262-72
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 1;195(7):3262-72
Tissue-Specific Education of Decidual NK Cells.
Sharkey AM, Xiong S, Kennedy PR, Gardner L, Farrell LE, Chazara O, Ivarsson MA, Hiby SE, Colucci F, Moffett A
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 1;195(7):3026-32
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 1;195(7):3026-32
2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.
Dunphy SE, Guinan KJ, Chorcora CN, Jayaraman J, Traherne JA, Trowsdale J, Pende D, Middleton D, Gardiner CM
Genes and immunity 2015 Jul-Aug;16(5):301-10
Genes and immunity 2015 Jul-Aug;16(5):301-10
KIR/HLA interactions negatively affect rituximab- but not GA101 (obinutuzumab)-induced antibody-dependent cellular cytotoxicity.
Terszowski G, Klein C, Stern M
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5618-24
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5618-24
Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients.
Achour A, Baychelier F, Besson C, Arnoux A, Marty M, Hannoun L, Samuel D, Debré P, Vieillard V, K-GREF Study Group.
Journal of immunology (Baltimore, Md. : 1950) 2014 Jan 1;192(1):503-11
Journal of immunology (Baltimore, Md. : 1950) 2014 Jan 1;192(1):503-11
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Charoudeh HN, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
European journal of immunology 2013 Feb;43(2):480-7
European journal of immunology 2013 Feb;43(2):480-7
Human immunodeficiency virus type 1 infection is associated with increased NK cell polyfunctionality and higher levels of KIR3DL1+ NK cells in ugandans carrying the HLA-B Bw4 motif.
Eller MA, Koehler RN, Kijak GH, Eller LA, Guwatudde D, Marovich MA, Michael NL, de Souza MS, Wabwire-Mangen F, Robb ML, Currier JR, Sandberg JK
Journal of virology 2011 May;85(10):4802-11
Journal of virology 2011 May;85(10):4802-11
Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.
Björkström NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M, Michaëlsson J, Malmberg KJ, Klingström J, Ahlm C, Ljunggren HG
The Journal of experimental medicine 2011 Jan 17;208(1):13-21
The Journal of experimental medicine 2011 Jan 17;208(1):13-21
No comments: Submit comment
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of KIR2DL1/KIR2DS5 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human KIR2DL1/KIR2DS5 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB1844F) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on isotype control antibody staining (Catalog # IC002F). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of KIR2DL1/KIR2DS5 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human KIR2DL1/KIR2DS5 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB1844F) or (B) Mouse IgG1 Isotype Control Antibody (Catalog # IC002F) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). View our protocol for Staining Membrane-associated Proteins.