FAB1847A

antibody from R&D Systems

Targeting: KIR2DS4

Flow cytometry (Recommended by provider)

Antibody Data

Product number

FAB1847A

Provider

R&D Systems

Product name

Anti-Human KIR2DS4/CD158i APC-conjugated Monoclonal Antibody (Clone 179315)

Antibody type

Monoclonal

Antigen

BaF3 mouse pro-B cell line transfected with human KIR2DS4

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Antigen sequence

P43632


Isotype

IgG

Vial size

100 Tests

References

Submitted references

2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.

Dunphy SE, Guinan KJ, Chorcora CN, Jayaraman J, Traherne JA, Trowsdale J, Pende D, Middleton D, Gardiner CM
Genes and immunity 2015 Jul-Aug;16(5):301-10

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CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients.

Béziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B, Theodorou I, Martinot M, Debré P, Björkström NK, Malmberg KJ, Marcellin P, Vieillard V
European journal of immunology 2012 Feb;42(2):447-57

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NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs.

Béziat V, Descours B, Parizot C, Debré P, Vieillard V
PloS one 2010 Aug 6;5(8):e11966