Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- MA5-18057 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-MCPH1 Monoclonal Antibody (AB11)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- This antibody recognizes the EDMD-associated lamin A/C mutant strain R453W. This target has a predicted molecular weight of 65 kDa.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- AB11
- Vial size
- 50 µL
- Concentration
- 1 mg/ml
- Storage
- Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Submitted references MCPH1 maintains long-term epigenetic silencing of ANGPT2 in chronic lymphocytic leukemia.
Kopparapu PK, Miranda C, Fogelstrand L, Mishra K, Andersson PO, Kanduri C, Kanduri M
The FEBS journal 2015 May;282(10):1939-52
The FEBS journal 2015 May;282(10):1939-52
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Immunofluorescent analysis of MCPH1/BRIT1 in COS cells expressing GFP microcephalin using a BRIT1 monoclonal antibody (Product # MA5-18057).