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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Western blot [2]
- Immunohistochemistry [2]
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- Product number
- 10365-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10365-1-AP, RRID:AB_2261615
- Product name
- DKK3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DKK3 antibody (Cat. #10365-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exercise ameliorates insulin resistance and improves ASK1-mediated insulin signalling in obese rats.
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
miR-1303 promotes the proliferation, migration and invasion of prostate cancer cells through regulating the Wnt/β-catenin pathway by targeting DKK3.
Bone secreted factors induce cellular quiescence in prostate cancer cells.
Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
MicroRNA-183 promotes the proliferation and metastasis of renal cell carcinoma through targeting Dickkopf-related protein 3.
Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines.
Properties of the feline tumour suppressor reduced expression in immortalized cells (REIC/Dkk-3).
Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
Molecular cloning and tumour suppressor function analysis of canine REIC/Dkk-3 in mammary gland tumours.
SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network.
microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancer.
Wnt antagonist DICKKOPF-3 (Dkk-3) induces apoptosis in human renal cell carcinoma.
Zhang Y, Ye T, Zhou P, Li R, Liu Z, Xie J, Hua T, Sun Q
Journal of cellular and molecular medicine 2021 Dec;25(23):10930-10938
Journal of cellular and molecular medicine 2021 Dec;25(23):10930-10938
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Wang L, Yu P, Zhou B, Song J, Li Z, Zhang M, Guo G, Wang Y, Chen X, Han L, Hu S
Nature cell biology 2020 Jan;22(1):108-119
Nature cell biology 2020 Jan;22(1):108-119
miR-1303 promotes the proliferation, migration and invasion of prostate cancer cells through regulating the Wnt/β-catenin pathway by targeting DKK3.
Liu B, Zhou W, Jiang H, Xiang Z, Wang L
Experimental and therapeutic medicine 2019 Dec;18(6):4747-4757
Experimental and therapeutic medicine 2019 Dec;18(6):4747-4757
Bone secreted factors induce cellular quiescence in prostate cancer cells.
Yu-Lee LY, Lee YC, Pan J, Lin SC, Pan T, Yu G, Hawke DH, Pan BF, Lin SH
Scientific reports 2019 Dec 9;9(1):18635
Scientific reports 2019 Dec 9;9(1):18635
Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, Ramachandran V, Arumugam T, Niehrs C, Wang H, Chiao P, Ling J, Curran MA, Maitra A, Hung MC, Lee JE, Logsdon CD, Hwang RF
Science translational medicine 2018 Oct 24;10(464)
Science translational medicine 2018 Oct 24;10(464)
MicroRNA-183 promotes the proliferation and metastasis of renal cell carcinoma through targeting Dickkopf-related protein 3.
Zhang XL, Xu G, Zhou Y, Yan JJ
Oncology letters 2018 Apr;15(4):6003-6008
Oncology letters 2018 Apr;15(4):6003-6008
Canine REIC/Dkk-3 interacts with SGTA and restores androgen receptor signalling in androgen-independent prostate cancer cell lines.
Kato Y, Ochiai K, Kawakami S, Nakao N, Azakami D, Bonkobara M, Michishita M, Morimatsu M, Watanabe M, Omi T
BMC veterinary research 2017 Jun 9;13(1):170
BMC veterinary research 2017 Jun 9;13(1):170
Properties of the feline tumour suppressor reduced expression in immortalized cells (REIC/Dkk-3).
Ochiai K, Oda H, Shono S, Kato Y, Sugihara S, Nakazawa S, Azakami D, Michishita M, Onozawa E, Bonkobara M, Sako T, Shun-Ai L, Ueki H, Watanabe M, Omi T
Veterinary and comparative oncology 2017 Dec;15(4):1181-1186
Veterinary and comparative oncology 2017 Dec;15(4):1181-1186
Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
Zhu Y, Demidov ON, Goh AM, Virshup DM, Lane DP, Bulavin DV
The Journal of clinical investigation 2014 Jul;124(7):3263-73
The Journal of clinical investigation 2014 Jul;124(7):3263-73
Molecular cloning and tumour suppressor function analysis of canine REIC/Dkk-3 in mammary gland tumours.
Ochiai K, Watanabe M, Azakami D, Michishita M, Yoshikawa Y, Udagawa C, Metheenukul P, Chahomchuen T, Aoki H, Kumon H, Morimatsu M, Omi T
Veterinary journal (London, England : 1997) 2013 Sep;197(3):769-75
Veterinary journal (London, England : 1997) 2013 Sep;197(3):769-75
SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network.
Li X, Xu Y, Chen Y, Chen S, Jia X, Sun T, Liu Y, Li X, Xiang R, Li N
Cancer letters 2013 Aug 19;336(2):379-89
Cancer letters 2013 Aug 19;336(2):379-89
microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancer.
Ueno K, Hirata H, Shahryari V, Deng G, Tanaka Y, Tabatabai ZL, Hinoda Y, Dahiya R
British journal of cancer 2013 Apr 30;108(8):1659-67
British journal of cancer 2013 Apr 30;108(8):1659-67
Wnt antagonist DICKKOPF-3 (Dkk-3) induces apoptosis in human renal cell carcinoma.
Ueno K, Hirata H, Majid S, Chen Y, Zaman MS, Tabatabai ZL, Hinoda Y, Dahiya R
Molecular carcinogenesis 2011 Jun;50(6):449-57
Molecular carcinogenesis 2011 Jun;50(6):449-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 10365-1-AP( DKK3 Antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10365-1-AP(DKK3 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 10365-1-AP(DKK3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DKK3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DKK3. This antibody recognizes human, mouse antigen. The DKK3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
