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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Immunocytochemistry [3]
- Other assay [1]
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- Product number
- PA3-200 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- SIRT2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA3-200 detects human and rat SIRT2 and shows no cross-reactivity to other SIRT isoforms. PA3-200 has been successfully used in Western blot and immunocytochemistry procedures. By Western blot, this antibody detects an ~48 kDa protein representing SIRT2 from SAOS2 cells. PA3-200 can be used for immunocytochemistry procedures. PA3-200 immunizing peptide corresponds to amino acid residues 341-352 from the human SIRT2 protein. This sequence is completely conserved between human and rat.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- Conc. Not Determined
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Transcriptional and Histochemical Signatures of Bone Marrow Mononuclear Cell-Mediated Resolution of Synovitis.
An Alternatively Spliced Sirtuin 2 Isoform 5 Inhibits Hepatitis B Virus Replication from cccDNA by Repressing Epigenetic Modifications Made by Histone Lysine Methyltransferases.
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection.
Adipose tissue-derived cells improve cardiac function following myocardial infarction.
Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function.
Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats.
Menarim BC, El-Sheikh Ali H, Loux SC, Scoggin KE, Kalbfleisch TS, MacLeod JN, Dahlgren LA
Frontiers in immunology 2021;12:734322
Frontiers in immunology 2021;12:734322
An Alternatively Spliced Sirtuin 2 Isoform 5 Inhibits Hepatitis B Virus Replication from cccDNA by Repressing Epigenetic Modifications Made by Histone Lysine Methyltransferases.
Piracha ZZ, Saeed U, Kim J, Kwon H, Chwae YJ, Lee HW, Lim JH, Park S, Shin HJ, Kim K
Journal of virology 2020 Jul 30;94(16)
Journal of virology 2020 Jul 30;94(16)
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection.
Eskandarian HA, Impens F, Nahori MA, Soubigou G, Coppée JY, Cossart P, Hamon MA
Science (New York, N.Y.) 2013 Aug 2;341(6145):1238858
Science (New York, N.Y.) 2013 Aug 2;341(6145):1238858
Adipose tissue-derived cells improve cardiac function following myocardial infarction.
Schenke-Layland K, Strem BM, Jordan MC, Deemedio MT, Hedrick MH, Roos KP, Fraser JK, Maclellan WR
The Journal of surgical research 2009 May 15;153(2):217-23
The Journal of surgical research 2009 May 15;153(2):217-23
Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function.
Shepard BD, Joseph RA, Kannarkat GT, Rutledge TM, Tuma DJ, Tuma PL
Hepatology (Baltimore, Md.) 2008 Nov;48(5):1671-9
Hepatology (Baltimore, Md.) 2008 Nov;48(5):1671-9
Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats.
Zhang Y, Xie ML, Xue J, Gu ZL
Journal of Asian natural products research 2008 Jul-Aug;10(7-8):807-12
Journal of Asian natural products research 2008 Jul-Aug;10(7-8):807-12
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of SIRT2 in transfected SAOS2 cells using Product # PA3-200.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of SIRT2 in transfected SAOS2 cells using Product # PA3-200.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of SIRT2 in transfected SAOS2 cells using Product # PA3-200.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
