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- References [403]
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- Product number
- 17490-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17490-1-AP, RRID:AB_2137880
- Product name
- MAP2 antibody
- Antibody type
- Polyclonal
- Description
- MAP2 antibody (Cat. #17490-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell-Mediated Repair Traumatic Brain Injury.
Clemastine ameliorates cognitive deficits in an experimental rat model of chronic cerebral hypoperfusion.
Single-cell transcriptomics reveals the mechanism of long-term neurodevelopmental toxicity following sevoflurane anesthesia.
The impact of tau deletion on Huntington's disease: An in vivo perspective.
Choroid plexus modulates subventricular zone adult neurogenesis and olfaction through secretion of small extracellular vesicles.
Sphingosine-1-Phosphate Receptor 3 Mediated Neuroinflammation is Critically Involved in the Development of Brain Injury Following Cardiac Arrest in Mice.
Adipose tissue-derived stromal cells enhance glycolytic metabolism in injured nerve cells via the FOXK1-HK2 axis for spinal cord injury repair.
C/EBPβ dictates postmenopausal FSHβ transcription and blockade of AEP/C/EBPβ pathway alleviates osteoporosis.
Endothelial cells temporally orchestrate lymphocyte dynamics and functional outcomes after ischemic stroke.
Synergistic Neuroprotective Effects of Taurine and Tauroursodeoxycholic Acid on the Neurovascular Unit in Hypoxia-Reoxygenation Injury.
Copper depletion ameliorates neuronal damage after intracerebral hemorrhage.
Plasma exosomal proteomics: Unveiling novel biomarkers for ischemic stroke in the context of diabetes.
A unified mechanism for mitochondrial damage sensing in PINK1-Parkin-mediated mitophagy.
The impact of repetitive neonatal procedural pain on cognitive behavioral development in male Mice: A microglial Perspective.
Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming.
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
SA supplementation during lactation promotes learning and memory by reducing H3K27me3 levels.
p62/SQSTM1 Condensation Modulates Mitochondrial Clustering to Participate in Mitochondrial Quality Control.
ISX9 activates the Wnt/β-catenin signaling pathway and exerts neuroprotective effects in Alzheimer's disease.
A modular platform for automated organoid culture and longitudinal imaging.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Early HMGB1 Inhibition Reduces Hippocampal Injury During Adolescence in a Young Mouse Model of Radiation-Induced Brain Injury.
Pathological axonal enlargement in connection with amyloidosis, lysosome destabilization, and bleeding is a major defect in Alzheimer's disease.
Retinol Taking a Detour Promotes Neural Stem Cell Self-Renewal In Vivo Accompanied by Down-Regulation of Some Retinoic Acid Receptors.
Kakkalide promotes spinal cord injury repair by regulating microglial M2 polarization via mitophagy.
Microfluidic Control of Dorsal-Ventral Patterning Within a Single Forebrain Organoid.
HIV and Cocaine exposure promote Tau phosphorylation through RSK-1 in a GSK3β-independent manner.
Astro-Versus Microglia-Enriched Transcriptomes from Aged Atxn2-CAG100-Knockin Mice Suggest Underlying Pathology of RNA Processing at Ribosomes, and Possibly at U-Bodies.
TP53/TAU axis regulates microtubule bundling to control alveolar stem cell-mediated regeneration.
Dendritic Morphology of Developing Hippocampal Neurons in Cyp11a1 Null Mice.
Low-Frequency (1 Hz) Repetitive Trans-Spinal Magnetic Stimulation Attenuates NLRP3-Driven Neuroinflammation and Enhances Motor Recovery in Spinal Cord-Injured Mice.
Distinct neuroprotective and anti-inflammatory effects of Kampo formulas ninjinyoeito and juzentaihoto in depression-like SAMP8 mice.
Exercise therapy facilitates neural remodeling and functional recovery post-spinal cord injury via PKA/CREB signaling pathway modulation in rats.
Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair.
Targeting the miR-96-5p/Cathepsin B Pathway to Alleviate Neuron-Derived Neuroinflammation in Alzheimer's Disease.
Repopulating Microglia Suppress Peripheral Immune Cell Infiltration to Promote Poststroke Recovery.
Preconditioning with an enriched environment enhances neuroplasticity and functional recovery following cerebral ischemia-reperfusion injury.
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Glioblastoma exploits ATP from leading-edge astrocytes to fuel its infiltrative growth revealed by spatially resolved chimeric analysis.
Glycyrrhizic acid combined with human adipose-derived MSCs synergistically alleviates the MPP+/MPTP-induced parkinson's disease by inducing autophagy through PI3K/AKT/HIF-1α pathway.
MicroRNA-502-3p Modulates the GABA A Subunits, Synaptic Proteins, and Mitochondrial Morphology in Hippocampal Neurons.
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria.
Salidroside attenuates the acquisition of morphine-induced conditioned place preference in mice via improving neurosynaptic plasticity in the ventral tegmental area.
Dual inhibition of IRAK1/TAK1 signaling in astrocytes reduces accelerated mortality in human APOE4 knock-in APPswe/PSEN1dE9/P301S-Tau triple transgenic mouse model.
Rapid and Simplified Induction of Spinal Motor Neurons From Human Induced Pluripotent Stem Cells.
Histone H3 lysine 18 lactylation attenuates neuroinflammation and neurological damage by regulating microglial plxnb2 after ischemic stroke.
Flexible Living Artificial Dura Mater for Efficient Therapy of Central Nervous System Injury Based on Neuronal Differentiation and Neuroprotective A2 Astrocyte Activation.
Chronic ethanol exposure induces hippocampal neuroinflammation and neuronal damage via the astrocytic RUNX1/TOLLIP/TLR3 pathway.
Social memory maintenance relies on social interaction-induced proteolytic products of neuroligin 1.
Synphilin-1 modulates alpha-synuclein assembly, release and uptake.
MCC950 attenuates thyroidectomy-induced retching-like behavior by inhibiting NLRP3-mediated IL-1β release.
Neurogenic inducers inhibit the proliferation of pancreatic cancer by promoting tumor cell transdifferentiation.
Pantothenic acid-mediated inhibition of microglial inflammation via the JAK2/STAT3 pathway enhances motor function recovery after Spinal cord injury.
Inhibition of CD36 ameliorates mouse spinal cord injury by accelerating microglial lipophagy.
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Distinct In Vitro Differentiation Protocols Differentially Affect Cytotoxicity Induced by Heavy Metals in Human Neuroblastoma SH-SY5Y Cells.
SLIT3-mediated intratumoral crosstalk induces neuroblastoma differentiation via a spontaneous regression-like program.
Self-Organizing Neural Networks in Organoids Reveal Principles of Forebrain Circuit Assembly.
Neuroprotective Effects of Qi Jing Wan and Its Active Ingredient Diosgenin Against Cognitive Impairment in Plateau Hypoxia.
Region-specific Brain Targets Drive Circuit Formation and Maturation of Human Retinal Ganglion Cells.
Allium Macrostemon Bge. Attenuates the Cognitive Decline of Aging Mice by Enhancing BDNF/TrkB Pathway.
Muscone enhances synaptic function in vascular dementia through activating BDNF-TrkB-NP2 signaling pathway.
Repair-associated macrophages increase after early-phase microglia attenuation to promote ischemic stroke recovery.
GPNMB and ATP6V1A interact to mediate microglia phagocytosis of multiple types of pathological particles.
Administration of Noggin Suppresses Fibrinogen Leakage into the Brain in the Acute Phase After Traumatic Brain Injury in Mice.
Autophagosomes anchor an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
Suppression of KDM5C mitigates the symptoms of Alzheimer's disease by up-regulating BDNF expression.
Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration.
Novel strategy to target glioblastoma-initiating cells using a braintropic adeno-associated virus carrying a miR-dependent genome-editing system.
The Epigenetic Reader PHF23 Is Required for Embryonic Neurogenesis.
Serum amyloid A drive microglia shift to a resolving phenotype through Nrf2.
Transcranial iTBS Combined With Trans-Spinal iTBS Targeting PDE1A/cAMP/PKA Axis Regulates Neural Regeneration After Spinal Cord Injury.
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy.
Refined qingkailing attenuates reactive astrocytes and glial scar formation after ischemia stroke via the EGFR/PLCγ pathway.
Neuronal FGF13 Inhibits Mitochondria-Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease.
The expression profile of type 1 equilibrative nucleoside transporter in aged C57BL/6J mouse brain.
Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a.
Ethyl Acetate Fraction of Zanthoxylum bungeanum Ameliorates Cognitive Deficit by Facilitating the PHGDH-Dependent Astrocyte-Neuron Serine Shuttle in Aging Mice.
Deficiency of Rab26 causes behavioral defects in mice through impaired trafficking of serotonin (5-HT) transporter.
The Upregulation of L1CAM by SVHRSP Mitigates Neuron Damage, Spontaneous Seizures, and Cognitive Dysfunction in a Kainic Acid-Induced Rat Model of Epilepsy.
THSG counteracts microglial glycolytic reprogramming and neuronal necroptosis both in vivo and in vitro under conditions of neuroinflammation.
Bioactive Peptide Hydrogel Scaffold with High Fluidity, Thermosensitivity, and Neurotropism in 3D Spatial Structure for Promoted Repair of Spinal Cord Injury.
BIN1 deficiency enhances ULK3-dependent autophagic flux and reduces dendritic size in mouse hippocampal neurons.
The important role of the Wnt/β-catenin signaling pathway in small molecules mediated gingival mesenchymal stem cells transdifferentiate into neuron-like cells.
Targeting of retrovirus-derived Rtl8a/8b causes late-onset obesity, reduced social response and increased apathy-like behaviour.
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Protosequences in brain organoids model intrinsic brain states Authors.
Altered ATP13A2/PARK9 Levels Influence α-Synuclein Accumulation in Neurons via Phagocytosis and Secretion in Glial Cells.
MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons.
The sigma-1 receptor-TAMM41 axis modulates neuroinflammation and attenuates memory impairment during the latent period of epileptogenesis.
CAMK2G Promotes Neuronal Differentiation and Inhibits Migration in Neuroblastoma.
Polyphenol Mediated Assembly: Tailored Nano-Dredger Unblocks Axonal Autophagosomes Retrograde Transport Traffic Jam for Accelerated Alzheimer's Waste Clearance.
The gut-brain axis underlying hepatic encephalopathy in liver cirrhosis.
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
The cholesterol 24-hydroxylase CYP46A1 promotes α-synuclein pathology in Parkinson's disease.
PLGA scaffold combined with MSCs transplantation improved neural function and brain tissue structure in rats with traumatic brain injury.
Microglia Process α-Synuclein Fibrils and Enhance their Pathogenicity in a TREM2-Dependent Manner.
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Urolithin A alleviates NLRP3 inflammasome activation and pyroptosis by promoting microglial mitophagy following spinal cord injury.
Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate.
Ageing-associated gut dysbiosis deteriorates mouse cognition.
Intraocular vasculature formation precedes extraocular vasculature penetration of mouse eyes.
PPP2/PP2A-mediated dephosphorylation of LC3B links PINK1-PRKN/Parkin-mediated mitophagy to SCA12 pathogenesis.
Melatonin improves synaptic morphological plasticity of adolescent male rats after perinatal BDE-209 exposure via SIRT1-mediated LIMK1 and CREB signaling.
Cholestanol promotes tau pathology in a mouse model of tauopathy.
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
From Microbiota to Metabolomics: How Corylus heterophylla Fisch. Male Flower Extract Shields Mice from Cognitive Decline.
Inhibiting MARS attenuates hyperhomocysteinemia-associated neurodegeneration in Parkinson's disease.
Galectin-9 activates microglial asparagine endopeptidase and promotes α-synuclein pathology in Parkinson's disease.
Astragaloside IV improves cognitive impairment in diabetes by inhibiting calpain-1/NLRP3 mediated microglial activation.
Nerve-to-cancer transfer of mitochondria during cancer metastasis.
Charting the spatial transcriptome of the human cerebral cortex at single-cell resolution.
Antisense oligonucleotide depletion of CCDC146 is a broad-spectrum therapeutic strategy for ALS.
Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure.
Fate plasticity of interneuron specification.
Luteolin attenuates cadmium neurotoxicity by suppressing glial inflammation and supporting neuronal survival.
Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson's disease-like neurodegeneration.
VEGF secreted by human dental pulp stem cell promotes spinal cord injury repair by inhibiting microglial pyroptosis through the PI3K/AKT pathway.
In vitro susceptibility of differentiated SH-SY5Y human neuroblastoma cells to herpes simplex virus type 1 and Japanese encephalitis virus infection.
The Effect of Differentiation of Human Dental Pulp Stem Cells to Glial Cells on the Sensory Nerves of the Dental Pulp.
Mitochondria-Rich Microvesicles Alleviate CNI ED by Transferring Mitochondria and Suppressing Local Ferroptosis.
Perioperative enriched environment attenuates postoperative cognitive dysfunction by upregulating microglia TREM2 via PI3K/Akt pathway in mouse model of ischemic stroke.
Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis.
Neuroprotective effects of ellorarxine in neuronal models of degeneration.
Single-cell RNA-sequencing analysis reveals α-syn induced astrocyte-neuron crosstalk-mediated neurotoxicity.
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
SOLID: minimizing tissue distortion for brain-wide profiling of diverse architectures.
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Thy1-ApoE4/C/EBPβ double transgenic mice act as a sporadic model with Alzheimer's disease.
Wnt/Ca(2+) pathway inhibits neural differentiation of human dental pulp stem cells in vitro.
IFN-β contributes to astrocyte activation in the brain following coronavirus PHEV infection independent on peripheral immunity.
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway.
Schwann cell-secreted frizzled-related protein 1 dictates neuroinflammation and peripheral nerve degeneration after neurotrauma.
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells.
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2-BECN1 interaction.
Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8(+) T cells in cerebral malaria.
Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus.
Wybutosine hypomodification of tRNAphe activates HERVK and impairs neuronal differentiation.
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
Disrupting PIAS3-mediated SUMOylation of MLK3 ameliorates poststroke neuronal damage and deficits in cognitive and sensorimotor behaviors.
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Protein expression of nucleolar protein 12 in the retina and its implication in protection of retina from UV irradiation damage.
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury.
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
CircRNA CDR1as affects functional repair after spinal cord injury and regulates fibrosis through the SMAD pathway.
Effects of a novel regimen of repetitive transcranial magnetic stimulation (rTMS) on neural remodeling and motor function in adult male mice with ischemic stroke.
Homozygosity for a Rare Plec Variant Suggests a Contributory Role in Congenital Insensitivity to Pain.
BCI Improves Alcohol-Induced Cognitive and Emotional Impairments by Restoring pERK-BDNF.
FMOD Alleviates Depression-Like Behaviors by Targeting the PI3K/AKT/mTOR Signaling After Traumatic Brain Injury.
Gliclazide Ameliorates Neuronal Injury by Attenuating Oxidative Stress in D-gal-Induced Senescent Cells and Aging Mice.
A Synthetic Steroid 5α-Androst-3β, 5, 6β-triol Alleviates Radiation-Induced Brain Injury in Mice via Inhibiting GBP5/NF-κB/NLRP3 Signal Axis.
The marine-derived compound TAG alleviates Parkinson's disease by restoring RUBCN-mediated lipid metabolism homeostasis.
PM2.5 triggers tau aggregation in a mouse model of tauopathy.
Toll-like receptor 4-dependent innate immune responses are mediated by intracrine corticosteroids and activation of glycogen synthase kinase-3β in astrocytes.
ERβ activation improves nonylphenol-induced depression and neurotransmitter secretion disruption via the TPH2/5-HT pathway.
Methylated urolithin A, mitigates cognitive impairment by inhibiting NLRP3 inflammasome and ameliorating mitochondrial dysfunction in aging mice.
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
Mannitol inhibits the proliferation of neural stem cell by a p38 mitogen-activated protein kinase-dependent signaling pathway.
A ROS-responsive loaded desferoxamine (DFO) hydrogel system for traumatic brain injury therapy.
Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters.
Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer.
Activation of testosterone-androgen receptor mediates cerebrovascular protection by photobiomodulation treatment in photothrombosis-induced stroke rats.
Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.
Disulfide bridge-targeted metabolome mining unravels an antiparkinsonian peptide.
The role of NF-κB signaling pathway in reactive astrocytes among neurodegeneration after methamphetamine exposure by integrated bioinformatics.
Sulbactam protects neurons against double neurotoxicity of amyloid beta and glutamate load by upregulating glial glutamate transporter 1.
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
Regulation of TAR DNA binding protein 43 (TDP-43) homeostasis by cytosolic DNA accumulation.
Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats.
Lycium barbarum oligosaccharide-derived carbon quantum dots inhibit glial scar formation while promoting neuronal differentiation of neural stem cells.
TLR3 Knockdown Attenuates Pressure-Induced Neuronal Damage In Vitro.
Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion and drug screening.
The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator.
The Role of KDM2A and H3K36me2 Demethylation in Modulating MAPK Signaling During Neurodevelopment.
Evidence of mutant huntingtin and tau-related pathology within neuronal grafts in Huntington's disease cases.
Ginsenoside Rg1 Regulates Immune Microenvironment and Neurological Recovery After Spinal Cord Injury Through MYCBP2 Delivery via Neuronal Cell-Derived Extracellular Vesicles.
Autophagosomes coordinate an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
SARS-CoV-2 Spike Protein S1 Domain Accelerates α-Synuclein Phosphorylation and Aggregation in Cellular Models of Synucleinopathy.
GDF1 ameliorates cognitive impairment induced by hearing loss.
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Age-Related Alterations in Peripheral Immune Landscape with Magnified Impact on Post-Stroke Brain.
Effects of early-life tosufloxacin tosilate hydrate administration on growth rate, neurobehavior, and gut microbiota at adulthood in male mice.
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy.
Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway.
Autologous olfactory mucosa mesenchymal stem cells treatment improves the neural network in chronic refractory epilepsy.
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Protocol for fine casting, imaging, and analysis of murine vascular networks with VALID.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
A novel small-molecular CCR5 antagonist promotes neural repair after stroke.
Exposure to nonylphenol in early life causes behavioural deficits related with autism spectrum disorders in rats.
Focal ischemic stroke modifies microglia-derived exosomal miRNAs: potential role of mir-212-5p in neuronal protection and functional recovery.
mNSCs overexpressing Rimkla transplantation facilitates cognitive recovery in a mouse model of traumatic brain injury.
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.
Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson's disease pathogenesis.
Cholestanol accelerates α-synuclein aggregation and spreading by activating asparagine endopeptidase.
The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease.
The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy.
The total alkaloids of Sophora alopecuroides L. improve depression-like behavior in mice via BDNF-mediated AKT/mTOR signaling pathway.
The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons.
Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6.
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Primary cilia TRP channel regulates hippocampal excitability.
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1.
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
Role of miR-219a-5p in regulating NMDAR in nonylphenol-induced synaptic plasticity damage.
Exposure to bisphenol A induces neurotoxicity associated with synaptic and cytoskeletal dysfunction in neuro-2a cells.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Overexpression of vascular endothelial growth factor enhances the neuroprotective effects of bone marrow mesenchymal stem cell transplantation in ischemic stroke.
A whole transcriptome profiling analysis for antidepressant mechanism of Xiaoyaosan mediated synapse loss via BDNF/trkB/PI3K signal axis in CUMS rats.
Islet amyloid polypeptide triggers α-synuclein pathology in Parkinson's disease.
Transient neurogenesis in ischemic cortex from Sox2(+) astrocytes.
Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury.
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
Atmospheric particulate matter impairs cognition by modulating synaptic function via the nose-to-brain route.
Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells.
Mitochondrial transplantation ameliorates hippocampal damage following status epilepticus.
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway.
Cofilin promotes tau pathology in Alzheimer's disease.
Effects of magnetically targeted iron oxide@polydopamine-labeled human umbilical cord mesenchymal stem cells in cerebral infarction in mice.
A versatile vessel casting method for fine mapping of vascular networks using a hydrogel-based lipophilic dye solution.
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model.
TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasis.
DLP printed hDPSC-loaded GelMA microsphere regenerates dental pulp and repairs spinal cord.
NRF2 activation suppresses motor neuron ferroptosis induced by the SOD1(G93A) mutation and exerts neuroprotection in amyotrophic lateral sclerosis.
Human forebrain organoid-based multi-omics analyses of PCCB as a schizophrenia associated gene linked to GABAergic pathways.
Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture.
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
Tubulin Isotypes and Posttranslational Modifications in Vascular Dementia and Alzheimer's Disease.
MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1(G93A) Motor Neuron of Amyotrophic Lateral Sclerosis.
High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats.
Rare KCND3 Loss-of-Function Mutation Associated With the SCA19/22.
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation.
DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis.
Tandem mass tag-based quantitative proteomic analysis of effects of multiple sevoflurane exposures on the cerebral cortex of neonatal and adult mice.
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model.
Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury.
Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects.
GPBAR1 preserves neurite and synapse of dopaminergic neurons via RAD21-OPCML signaling: Role in preventing Parkinson's disease in mouse model and human patients.
Therapeutic Effect of Biomimetic Scaffold Loaded with Human Amniotic Epithelial Cell-Derived Neural-like Cells for Spinal Cord Injury.
Ectosomes and exosomes modulate neuronal spontaneous activity.
Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice.
Tau accelerates α-synuclein aggregation and spreading in Parkinson's disease.
Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia-Reperfusion Injury in Mice.
A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats.
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
SKF83959 Attenuates Memory Impairment and Depressive-like Behavior during the Latent Period of Epilepsy via Allosteric Activation of the Sigma-1 Receptor.
miR-92a-2-5p Regulates the Proliferation and Differentiation of ASD-Derived Neural Progenitor Cells.
The LPA-CDK5-tau pathway mediates neuronal injury in an in vitro model of ischemia-reperfusion insult.
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Recombinant human erythropoietin protects long-term cultured ageing primary nerve cells by upregulating the PI3K/Akt pathway.
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8(+) T cells.
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
Electroacupuncture treatment improves motor function and neurological outcomes after cerebral ischemia/reperfusion injury.
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis.
Exploring the pharmacological mechanism of calculus bovis in cerebral ischaemic stroke using a network pharmacology approach.
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease.
CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons.
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function.
A functional SNP rs895819 on pre-miR-27a is associated with bipolar disorder by targeting NCAM1.
Low-Intensity Ultrasound Causes Direct Excitation of Auditory Cortical Neurons.
Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression.
Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo.
Transgenic Mice Expressing Human α-Synuclein 1-103 Fragment as a Novel Model of Parkinson's Disease.
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
The Role of HSP90α in Methamphetamine/Hyperthermia-Induced Necroptosis in Rat Striatal Neurons.
Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
Maternal Ethanol Exposure Acutely Elevates Src Family Kinase Activity in the Fetal Cortex.
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Kir6.2 is essential to maintain neurite features by modulating PM20D1-reduced mitochondrial ATP generation.
Remote Limb Ischemic Postconditioning Protects Against Ischemic Stroke by Promoting Regulatory T Cells Thriving.
In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury.
Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice.
XQ-1H promotes cerebral angiogenesis via activating PI3K/Akt/GSK3β/β-catenin/VEGF signal in mice exposed to cerebral ischemic injury.
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage.
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Edaravone attenuates H(2)O(2) or glutamate-induced toxicity in hippocampal neurons and improves AlCl(3)/D-galactose induced cognitive impairment in mice.
3D printable Sodium alginate-Matrigel (SA-MA) hydrogel facilitated ectomesenchymal stem cells (EMSCs) neuron differentiation.
Defective biosynthesis of ascorbic acid in Sod1-deficient mice results in lethal damage to lung tissue.
Protection of hUC-MSCs against neuronal complement C3a receptor-mediated NLRP3 activation in CUMS-induced mice.
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Effects of the histone acetylase inhibitor C646 on growth and differentiation of adipose-derived stem cells.
EGB761 ameliorates chronic cerebral hypoperfusion-induced cognitive dysfunction and synaptic plasticity impairment.
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice.
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Qingxin Kaiqiao Fang Inhibits Aβ (25-35)-Induced Apoptosis in Primary Cultured Rat Hippocampal Neuronal Cells via the p38 MAPK Pathway: An Experimental Validation and Network Pharmacology Study.
Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation.
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
RNA Binding Protein Motif 3 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Apoptosis Through Promoting Stress Granules Formation in PC12 Cells and Rat Primary Cortical Neurons.
Ablation of GSDMD Improves Outcome of Ischemic Stroke Through Blocking Canonical and Non-canonical Inflammasomes Dependent Pyroptosis in Microglia.
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Cofilin 1 promotes the aggregation and cell-to-cell transmission of α-synuclein in Parkinson's disease.
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Neuron-Derived Estrogen Is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain.
SARS-CoV-2 targets neurons of 3D human brain organoids.
5-HT(1A)R alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
Dose-dependent effects of tetramethylpyrazine on the characteristics of human umbilical cord mesenchymal stem cells for stroke therapy.
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
Rapid and Efficient Invasion Assay of Glioblastoma in Human Brain Organoids.
Single-Cell Analysis for Glycogen Localization and Metabolism in Cultured Astrocytes.
Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates.
Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles.
Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
MicroRNA Let-7b-5p Induces Electroacupuncture Tolerance by Downregulating the MKP-1 Gene in Rats Subjected to CFA-induced Inflammatory Nociception.
Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro.
High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia.
Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2.
A dual-enzymatically cross-linked injectable gelatin hydrogel loaded with BMSC improves neurological function recovery of traumatic brain injury in rats.
Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats.
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
Probucol, a "non-statin" cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice.
Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure.
Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion.
Talin promotes integrin activation accompanied by generation of tension in talin and an increase in osmotic pressure in neurite outgrowth.
Multi-site dynamic recording for Aβ oligomers-induced Alzheimer's disease in vitro based on neuronal network chip.
Treadmill exercise ameliorates focal cerebral ischemia/reperfusion-induced neurological deficit by promoting dendritic modification and synaptic plasticity via upregulating caveolin-1/VEGF signaling pathways.
Inhibitory effects of glucagon-like peptide-1 receptor on epilepsy.
Memantine can relieve the neuronal impairment caused by neurotropic virus infection.
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Geniposide ameliorated fluoxetine-suppressed neurite outgrowth in Neuro2a neuroblastoma cells.
Lentiviral-mediated ephrin B2 gene modification of rat bone marrow mesenchymal stem cells.
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Zn(2+) Aggravates Tau Aggregation and Neurotoxicity.
Microglia as modulators of exosomal alpha-synuclein transmission.
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
JC virus infection of meningeal and choroid plexus cells in patients with progressive multifocal leukoencephalopathy.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
A single factor induces neuronal differentiation to suppress glioma cell growth.
Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice.
In Vitro Neural Differentiation of Bone Marrow Mesenchymal Stem Cells Carrying the FTH1 Reporter Gene and Detection with MRI.
Perineurial-like Cells and EMA Expression in the Suprachoroidal Region of the Human Eye.
Pitavastatin treatment induces neuroprotection through the BDNF-TrkB signalling pathway in cultured cerebral neurons after oxygen-glucose deprivation.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Neuroserpin restores autophagy and promotes functional recovery after acute spinal cord injury in rats.
Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence.
Outcome of cell suspension allografts in a patient with Huntington's disease.
REST overexpression in mice causes deficits in spontaneous locomotion.
Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing.
Improved Neural Regeneration with Olfactory Ensheathing Cell Inoculated PLGA Scaffolds in Spinal Cord Injury Adult Rats.
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission.
miR-200c regulates endothelin-1 induced PASMCs abnormal proliferation and apoptosis.
Involvement of intracellular transport in TREK-1c current run-up in 293T cells.
Anterograde monosynaptic transneuronal tracers derived from herpes simplex virus 1 strain H129.
Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids.
Neuropeptide Y suppresses epileptiform discharges by regulating AMPA receptor GluR2 subunit in rat hippocampal neurons.
RNA stores tau reversibly in complex coacervates.
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Mutant huntingtin protein expression and blood-spinal cord barrier dysfunction in huntington disease.
Transplantation of VEGF-mediated bone marrow mesenchymal stem cells promotes functional improvement in a rat acute cerebral infarction model.
rhEPO Enhances Cellular Anti-oxidant Capacity to Protect Long-Term Cultured Aging Primary Nerve Cells.
Claulansine F promoted the neuronal differentiation of neural stem and progenitor cells through Akt/GSK-3β/β-catenin pathway.
Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells.
Human-to-mouse prion-like propagation of mutant huntingtin protein.
Evaluation of histopathological changes in the microstructure at the center and periphery of glioma tumors using diffusional kurtosis imaging.
Endoplasmic reticulum stress mediates JNK-dependent IRS-1 serine phosphorylation and results in Tau hyperphosphorylation in amyloid β oligomer-treated PC12 cells and primary neurons.
Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury.
Headless Myo10 is a regulator of microtubule stability during neuronal development.
Viral Infection of the Central Nervous System and Neuroinflammation Precede Blood-Brain Barrier Disruption during Japanese Encephalitis Virus Infection.
Increased stathmin expression strengthens fear conditioning in epileptic rats.
Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells.
The effects of harvesting media on biological characteristics and repair potential of neural stem cells after traumatic brain injury.
AxonQuant: A Microfluidic Chamber Culture-Coupled Algorithm That Allows High-Throughput Quantification of Axonal Damage.
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury.
Neuropeptide Y protects cerebral cortical neurons by regulating microglial immune function.
Mutant huntingtin is present in neuronal grafts in Huntington disease patients.
Effects of targeted suppression of glutaryl-CoA dehydrogenase by lentivirus-mediated shRNA and excessive intake of lysine on apoptosis in rat striatal neurons.
Zhou P, Wu Q, Wu Y, Huang R, Li W, Niu H, Sun H, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e24326
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(27):e24326
Clemastine ameliorates cognitive deficits in an experimental rat model of chronic cerebral hypoperfusion.
Zong X, Huang Z, Kong F, Feng Y, Zhang Y, Zou P, Wen Lin H, Hess DC, Zhang Q
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Mar;46(3):786-803
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Mar;46(3):786-803
Single-cell transcriptomics reveals the mechanism of long-term neurodevelopmental toxicity following sevoflurane anesthesia.
Xu J, Wang Z, Wang H, Wen H, Wen Z, Chen L, Cheng Y, Yan J, Jiang H
Neurotoxicology 2026 Mar;113:103402
Neurotoxicology 2026 Mar;113:103402
The impact of tau deletion on Huntington's disease: An in vivo perspective.
Lepinay E, Saint-Pierre M, Teixeira M, Snapyan M, Oueslati A, Parent M, Alpaugh M, Cicchetti F
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Mar 4;34(3):1836-1853
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Mar 4;34(3):1836-1853
Choroid plexus modulates subventricular zone adult neurogenesis and olfaction through secretion of small extracellular vesicles.
Liu LL, Shannahan J, Zheng W
Fluids and barriers of the CNS 2026 Mar 31;23(1)
Fluids and barriers of the CNS 2026 Mar 31;23(1)
Sphingosine-1-Phosphate Receptor 3 Mediated Neuroinflammation is Critically Involved in the Development of Brain Injury Following Cardiac Arrest in Mice.
Wang X, Cai SQ, Gao Y, Fan JJ, Ren LW, Gao HC, Chen XD, Duan ML
Neurochemical research 2026 Mar 19;51(2)
Neurochemical research 2026 Mar 19;51(2)
Adipose tissue-derived stromal cells enhance glycolytic metabolism in injured nerve cells via the FOXK1-HK2 axis for spinal cord injury repair.
Li F, Li H, Jia Y, Ou L, Fang Y, Pan L, Liu H, Ning B
Journal of translational medicine 2026 Mar 17;24(1)
Journal of translational medicine 2026 Mar 17;24(1)
C/EBPβ dictates postmenopausal FSHβ transcription and blockade of AEP/C/EBPβ pathway alleviates osteoporosis.
Xie Z, Liao J, Xiong J, Zhao Z, Ye K
Bone research 2026 Mar 17;14(1)
Bone research 2026 Mar 17;14(1)
Endothelial cells temporally orchestrate lymphocyte dynamics and functional outcomes after ischemic stroke.
Zhou Y, Yang F, Lu Y, Yu G, Wang J, Li H
Fluids and barriers of the CNS 2026 Mar 14;23(1)
Fluids and barriers of the CNS 2026 Mar 14;23(1)
Synergistic Neuroprotective Effects of Taurine and Tauroursodeoxycholic Acid on the Neurovascular Unit in Hypoxia-Reoxygenation Injury.
Du X, Li SY, Wu GL, Cai HY, Sun CY, Lin H, Cai YF, Wang Q
Rejuvenation research 2026 Jun;29(3):131-145
Rejuvenation research 2026 Jun;29(3):131-145
Copper depletion ameliorates neuronal damage after intracerebral hemorrhage.
Zhang W, Wu G, Wang L, Ren S
Neurochemistry international 2026 Jun;196:106150
Neurochemistry international 2026 Jun;196:106150
Plasma exosomal proteomics: Unveiling novel biomarkers for ischemic stroke in the context of diabetes.
Jiang Q, Peng G, Kong Q, Zhou Y, Zhao H, Geng X
Brain research bulletin 2026 Jun 1;239:111884
Brain research bulletin 2026 Jun 1;239:111884
A unified mechanism for mitochondrial damage sensing in PINK1-Parkin-mediated mitophagy.
Thayer JA, Petersen JD, Huang X, Gruel Budet LM, Hawrot J, Ramos DM, Sekine S, Li Y, Ward ME, Narendra DP
The EMBO journal 2026 Jan;45(1):64-105
The EMBO journal 2026 Jan;45(1):64-105
The impact of repetitive neonatal procedural pain on cognitive behavioral development in male Mice: A microglial Perspective.
Wang Y, Ling R, Zheng W, Xia D, Min C, Chen M, Zhou W, Li X
Brain, behavior, and immunity 2026 Jan;131:106182
Brain, behavior, and immunity 2026 Jan;131:106182
Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming.
Zhu L, Wang W, Zhang J, Liu L, Huang M, Diao L, Feng S, Yang Q, Qiu H, Pan B, Pera RAR, Liu J, Xia N, Fang F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e10641
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e10641
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Li Y, Lu W, Qian W, Liao X, Wang P, Wang Y, Jiao W, Wang M, Zhao J, Yang J, Gao H, Li H
Nutrients 2026 Jan 19;18(2)
Nutrients 2026 Jan 19;18(2)
SA supplementation during lactation promotes learning and memory by reducing H3K27me3 levels.
Huang C, Ai S, Wang M, Li C, Wang K, Nie M, Zhang H, Gu X, Wang HL
Journal of advanced research 2026 Feb;80:301-316
Journal of advanced research 2026 Feb;80:301-316
p62/SQSTM1 Condensation Modulates Mitochondrial Clustering to Participate in Mitochondrial Quality Control.
Sun S, Xin J, Zhang Y, Yang B, Su D, Ni R, Ma Q, Li N, Ma G, Peng Q, Chen S, Prehn JHM, Tam KY, Wang H, Ying Z
Aging cell 2026 Feb;25(2):e70402
Aging cell 2026 Feb;25(2):e70402
ISX9 activates the Wnt/β-catenin signaling pathway and exerts neuroprotective effects in Alzheimer's disease.
Xiao J, Liu Y, Peng M, Ma J, Lei S, Chen Y, Liu S, Zhao X, Lu D, Sun Q
Alzheimer's research & therapy 2026 Feb 5;18(1)
Alzheimer's research & therapy 2026 Feb 5;18(1)
A modular platform for automated organoid culture and longitudinal imaging.
Torres-Montoya S, Hernandez S, Seiler ST, Schweiger HE, Vera-Choqqueccota S, Kaurala G, Sharf T, Haussler D, Mostajo-Radji MA, Teodorescu M
Scientific reports 2026 Feb 18;16(1)
Scientific reports 2026 Feb 18;16(1)
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Early HMGB1 Inhibition Reduces Hippocampal Injury During Adolescence in a Young Mouse Model of Radiation-Induced Brain Injury.
Sun Y, Shi M, Ma L, Xie H, Hei M, Zuo W
Cellular and molecular neurobiology 2026 Feb 10;46(1)
Cellular and molecular neurobiology 2026 Feb 10;46(1)
Pathological axonal enlargement in connection with amyloidosis, lysosome destabilization, and bleeding is a major defect in Alzheimer's disease.
Fu H, Li J, Zhang C, Gao G, Ge Q, Guan X, Cui D
Neural regeneration research 2026 Feb 1;21(2):790-799
Neural regeneration research 2026 Feb 1;21(2):790-799
Retinol Taking a Detour Promotes Neural Stem Cell Self-Renewal In Vivo Accompanied by Down-Regulation of Some Retinoic Acid Receptors.
Chen L, Chen EW, Chen BW, Wang D
Stem cells and development 2026 Apr;35(7-8):144-151
Stem cells and development 2026 Apr;35(7-8):144-151
Kakkalide promotes spinal cord injury repair by regulating microglial M2 polarization via mitophagy.
You T, Dai B, Ding X, He Z, Peng J, Tao S, Ye L, Song T, Fan Z, Chen N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157985
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157985
Microfluidic Control of Dorsal-Ventral Patterning Within a Single Forebrain Organoid.
Torres-Montoya S, Vera-Choqqueccota S, Seiler ST, Haussler D, Salama SR, Mostajo-Radji MA, Teodorescu M
bioRxiv : the preprint server for biology 2026 Apr 8;
bioRxiv : the preprint server for biology 2026 Apr 8;
HIV and Cocaine exposure promote Tau phosphorylation through RSK-1 in a GSK3β-independent manner.
Sharma AL, Sariyer IK, Naik UP, Tyagi M
bioRxiv : the preprint server for biology 2026 Apr 16;
bioRxiv : the preprint server for biology 2026 Apr 16;
Astro-Versus Microglia-Enriched Transcriptomes from Aged Atxn2-CAG100-Knockin Mice Suggest Underlying Pathology of RNA Processing at Ribosomes, and Possibly at U-Bodies.
Auburger G, Kandi AR, Vutukuri R, Almaguer-Mederos LE, Gispert S, Sen NE, Key J
Cells 2026 Apr 15;15(8)
Cells 2026 Apr 15;15(8)
TP53/TAU axis regulates microtubule bundling to control alveolar stem cell-mediated regeneration.
Konishi S, Enkhbayar K, Liu S, Miyashita N, Kobayashi Y, Hutchison V, Sai A, Agarwal P, Witonsky J, Jackson ND, Seibold MA, Chen J, Tata A, Tata PR
The Journal of clinical investigation 2026 Apr 1;136(7)
The Journal of clinical investigation 2026 Apr 1;136(7)
Dendritic Morphology of Developing Hippocampal Neurons in Cyp11a1 Null Mice.
Jiang HH, Wu TH, Lee LJ, Lee JC, Chung BC, Yang FM, Hu MC
Developmental neuroscience 2025;47(3):157-171
Developmental neuroscience 2025;47(3):157-171
Low-Frequency (1 Hz) Repetitive Trans-Spinal Magnetic Stimulation Attenuates NLRP3-Driven Neuroinflammation and Enhances Motor Recovery in Spinal Cord-Injured Mice.
Song H, Yang Y, Huang L, Li Y, Sun B, Yu Z, Zhang M, Yang D
Journal of inflammation research 2025;18:11263-11284
Journal of inflammation research 2025;18:11263-11284
Distinct neuroprotective and anti-inflammatory effects of Kampo formulas ninjinyoeito and juzentaihoto in depression-like SAMP8 mice.
Maruko A, Ito N, Oshima K, Nishi A, Kobayashi Y, Okada N
Frontiers in pharmacology 2025;16:1600176
Frontiers in pharmacology 2025;16:1600176
Exercise therapy facilitates neural remodeling and functional recovery post-spinal cord injury via PKA/CREB signaling pathway modulation in rats.
Ying X, Xie Q, Zhao Y, Shen J, Huang J, Feng Z, Chu L, Xu J, Jiang D, Wu P, Zuo Y, Li S, Jiang C, Li X, Wang Z
Burns & trauma 2025;13:tkae058
Burns & trauma 2025;13:tkae058
Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair.
Yu H, Liu F, Hu Y, Wan W, Liu Q, Zhou S, Zhang L, Li L, Huang F
Frontiers in bioengineering and biotechnology 2025;13:1618680
Frontiers in bioengineering and biotechnology 2025;13:1618680
Targeting the miR-96-5p/Cathepsin B Pathway to Alleviate Neuron-Derived Neuroinflammation in Alzheimer's Disease.
Zheng K, Huang HZ, Liu D, Brazhe N, Chen J, Zhu LQ
MedComm 2025 Sep;6(9):e70368
MedComm 2025 Sep;6(9):e70368
Repopulating Microglia Suppress Peripheral Immune Cell Infiltration to Promote Poststroke Recovery.
Shi L, Lu L, Hu J, Chen J, Zhang Q, Jin Z, Wang Z, Zheng Z, Zhang J
CNS neuroscience & therapeutics 2025 Sep;31(9):e70565
CNS neuroscience & therapeutics 2025 Sep;31(9):e70565
Preconditioning with an enriched environment enhances neuroplasticity and functional recovery following cerebral ischemia-reperfusion injury.
Zhang Y, Liu W, Liu L, Liu Y, Yang Y, Yang Z, Chen X
Brain research bulletin 2025 Sep;229:111459
Brain research bulletin 2025 Sep;229:111459
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Zhou Y, Xu T, Zhou Y, Chen N, Wu Z, Yang Z, Yang C, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Glioblastoma exploits ATP from leading-edge astrocytes to fuel its infiltrative growth revealed by spatially resolved chimeric analysis.
Yang G, Niu X, Gan J, Yu T, Li M, Xiao P, Zhang R, He P, Yang Y, Cui Y, Huang X, Wang Y, Mao Q, Zhou R
Science advances 2025 Sep 26;11(39):eadv5673
Science advances 2025 Sep 26;11(39):eadv5673
Glycyrrhizic acid combined with human adipose-derived MSCs synergistically alleviates the MPP+/MPTP-induced parkinson's disease by inducing autophagy through PI3K/AKT/HIF-1α pathway.
Yu X, Fang Y, Zhang J, Li W, Zhang Y, Cui Q, Liu X, Jiang Y, Liu Q, Xu C, Jiang B, Lu Y
Stem cell research & therapy 2025 Sep 25;16(1):500
Stem cell research & therapy 2025 Sep 25;16(1):500
MicroRNA-502-3p Modulates the GABA A Subunits, Synaptic Proteins, and Mitochondrial Morphology in Hippocampal Neurons.
Sharma B, Rodarte D, Goyal G, Rodriguez S, Kumar S
Molecular neurobiology 2025 Oct;62(10):13479-13499
Molecular neurobiology 2025 Oct;62(10):13479-13499
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria.
Wang J, Zhu Q, Tong G, Yu K, Liang J, Huang Y, Wang Y, Yang C, Li T, Liang W, Li G, Liu X, Sun J, Li Y, Shen Y, Zhao Y
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2385-2400
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2385-2400
Salidroside attenuates the acquisition of morphine-induced conditioned place preference in mice via improving neurosynaptic plasticity in the ventral tegmental area.
Li Z, Mu X, Wang Q, Zhou Z, Wang Z, Wang Y, Liu Q, Lin W, Qin F, Pan H, Huang J, Gu Y, Li Q, Jiang Y, Lu S, Wang Q, Tan S, Lu Z
British journal of pharmacology 2025 Oct;182(19):4553-4577
British journal of pharmacology 2025 Oct;182(19):4553-4577
Dual inhibition of IRAK1/TAK1 signaling in astrocytes reduces accelerated mortality in human APOE4 knock-in APPswe/PSEN1dE9/P301S-Tau triple transgenic mouse model.
Lei C, Zhang B, Yamaguchi J, Tamura R, Zhong W, Cao X, Liu Y, Seki M, Suzuki Y, Suzuki K, Tanida I, Uchiyama Y, Hisatsune T
Journal of neuroinflammation 2025 Oct 21;22(1):237
Journal of neuroinflammation 2025 Oct 21;22(1):237
Rapid and Simplified Induction of Spinal Motor Neurons From Human Induced Pluripotent Stem Cells.
Chen Y, Yang F, O'Brien T, Shen S, Yang M
Bio-protocol 2025 Oct 20;15(20):e5478
Bio-protocol 2025 Oct 20;15(20):e5478
Histone H3 lysine 18 lactylation attenuates neuroinflammation and neurological damage by regulating microglial plxnb2 after ischemic stroke.
Li P, Wang Y, Xu Y, Feng L, Jiang N, Fang Y, Song G, Yu L, Xu L, Zhu Z, Zhu S, Wang W, Xie M
Neurobiology of disease 2025 Oct 15;215:107061
Neurobiology of disease 2025 Oct 15;215:107061
Flexible Living Artificial Dura Mater for Efficient Therapy of Central Nervous System Injury Based on Neuronal Differentiation and Neuroprotective A2 Astrocyte Activation.
Yang H, Liu H, Lou C, Han M, Sun Z, Su Y, Bian K, Zhao D, Li Y, Sang Y, Liu C, Geng Z, Liu H, Qiu J
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(45):e11878
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(45):e11878
Chronic ethanol exposure induces hippocampal neuroinflammation and neuronal damage via the astrocytic RUNX1/TOLLIP/TLR3 pathway.
Shen H, Zhang Q, Lv Q, Liu H, Wang C, Meng F, Guo Y, Pei J, Yu C, Tie J, Chen X, Zhang C, Yu H, Wang X
Brain, behavior, and immunity 2025 Nov;130:106081
Brain, behavior, and immunity 2025 Nov;130:106081
Social memory maintenance relies on social interaction-induced proteolytic products of neuroligin 1.
Liu A, Li X, Zhuang M, Ren Q, Zhang J, Lv D, Wu M, Bian X, Zhu C, Yang X, Li M, Wang Y, Jia Z, Xie W
Signal transduction and targeted therapy 2025 Nov 24;10(1):387
Signal transduction and targeted therapy 2025 Nov 24;10(1):387
Synphilin-1 modulates alpha-synuclein assembly, release and uptake.
Lázaro DF, Amen T, Gerhardt E, Song C, Burns R, Kruse N, Santos PI, Milovanovic D, Höglinger G, Mollenhauer B, Luk KC, Lee VM, Outeiro TF
NPJ Parkinson's disease 2025 Nov 20;11(1):326
NPJ Parkinson's disease 2025 Nov 20;11(1):326
MCC950 attenuates thyroidectomy-induced retching-like behavior by inhibiting NLRP3-mediated IL-1β release.
Li LX, Li WG, Ma XY, Wang XP, Liu SZ, Ji ZS, Gao Y, Zhang LM
International immunopharmacology 2025 Nov 14;165:115541
International immunopharmacology 2025 Nov 14;165:115541
Neurogenic inducers inhibit the proliferation of pancreatic cancer by promoting tumor cell transdifferentiation.
Guo D, Shi S, Ye L, Yang M, Peng W, Yang J, Xu J, Fei Q, Li H, Jin K, Hu X, Wu W
Journal of experimental & clinical cancer research : CR 2025 Nov 12;44(1):304
Journal of experimental & clinical cancer research : CR 2025 Nov 12;44(1):304
Pantothenic acid-mediated inhibition of microglial inflammation via the JAK2/STAT3 pathway enhances motor function recovery after Spinal cord injury.
Fang Y, Zhang C, Yang Z, Zhao X, Yongcheng Yin, Zhengxin Jin, Zhu P, Ning B
Neuropharmacology 2025 Nov 1;278:110591
Neuropharmacology 2025 Nov 1;278:110591
Inhibition of CD36 ameliorates mouse spinal cord injury by accelerating microglial lipophagy.
Wang BN, Du AY, Chen XH, Huang T, Mamun AA, Li P, Du ST, Feng YZ, Jiang LY, Xu J, Wang Y, Wang SS, Kim K, Zhou KL, Wu YQ, Hu SW, Xiao J
Acta pharmacologica Sinica 2025 May;46(5):1205-1220
Acta pharmacologica Sinica 2025 May;46(5):1205-1220
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Cao MM, Guo Z, Wang J, Ma HY, Qin XY, Hu Y, Lan R
Free radical biology & medicine 2025 May;232:340-352
Free radical biology & medicine 2025 May;232:340-352
Distinct In Vitro Differentiation Protocols Differentially Affect Cytotoxicity Induced by Heavy Metals in Human Neuroblastoma SH-SY5Y Cells.
Ferdous J, Naitou K, Shiraishi M
Biological trace element research 2025 May;203(5):2595-2605
Biological trace element research 2025 May;203(5):2595-2605
SLIT3-mediated intratumoral crosstalk induces neuroblastoma differentiation via a spontaneous regression-like program.
Liu M, Lv D, Yan W, Wu Y, Wang S, Wang L, Lei J, Zeng D, Wang Z, Liu F, Deng B, Liu Q, He B, Yan M
Journal of translational medicine 2025 May 30;23(1):598
Journal of translational medicine 2025 May 30;23(1):598
Self-Organizing Neural Networks in Organoids Reveal Principles of Forebrain Circuit Assembly.
Hernandez S, Schweiger HE, Cline I, Kaurala GA, Robbins A, Solis D, Geng J, van der Molen T, Reyes F, Asogwa CN, Voitiuk K, Chini M, Rolandi M, Salama SR, Colquitt BM, Sharf T, Haussler D, Teodorescu M, Mostajo-Radji MA
bioRxiv : the preprint server for biology 2025 May 2;
bioRxiv : the preprint server for biology 2025 May 2;
Neuroprotective Effects of Qi Jing Wan and Its Active Ingredient Diosgenin Against Cognitive Impairment in Plateau Hypoxia.
Xia T, Yan Z, Shen P, Chang M, Zhang N, Zhang Y, Chen Q, Wang R, Tong L, Zhou W, Ni Z, Gao Y
Pharmaceuticals (Basel, Switzerland) 2025 May 17;18(5)
Pharmaceuticals (Basel, Switzerland) 2025 May 17;18(5)
Region-specific Brain Targets Drive Circuit Formation and Maturation of Human Retinal Ganglion Cells.
Huang KC, Jeng HY, Abdulwahab Q, Cuevas VR, Shihabeddin E, Young C, Hernandez M, Meyer JS, Tran NM, Samuel MA
bioRxiv : the preprint server for biology 2025 May 10;
bioRxiv : the preprint server for biology 2025 May 10;
Allium Macrostemon Bge. Attenuates the Cognitive Decline of Aging Mice by Enhancing BDNF/TrkB Pathway.
Sheng R, Zhao M, Pu K, Zhou Y, Zeng L, Chen Y, Wang P, Liu X, Xu S
Food science & nutrition 2025 Mar;13(3):e70010
Food science & nutrition 2025 Mar;13(3):e70010
Muscone enhances synaptic function in vascular dementia through activating BDNF-TrkB-NP2 signaling pathway.
Huang P, Sun H, Chen Y, Li J, Peng Y, Ge C, Zhu K, Zhou X, Chang D, Wang N
International immunopharmacology 2025 Mar 6;149:114232
International immunopharmacology 2025 Mar 6;149:114232
Repair-associated macrophages increase after early-phase microglia attenuation to promote ischemic stroke recovery.
Zhang X, Li H, Gu Y, Ping A, Chen J, Zhang Q, Xu Z, Wang J, Tang S, Wang R, Lu J, Lu L, Jin C, Jin Z, Zhang J, Shi L
Nature communications 2025 Mar 31;16(1):3089
Nature communications 2025 Mar 31;16(1):3089
GPNMB and ATP6V1A interact to mediate microglia phagocytosis of multiple types of pathological particles.
Liu M, Zhu J, Zheng J, Han X, Jiang L, Tong X, Ke Y, Guo Z, Huang W, Cong J, Liu M, Lin SY, Zhu S, Mei L, Zhang X, Zhang W, Xin WJ, Zhang Z, Guo Y, Chen R
Cell reports 2025 Mar 25;44(3):115343
Cell reports 2025 Mar 25;44(3):115343
Administration of Noggin Suppresses Fibrinogen Leakage into the Brain in the Acute Phase After Traumatic Brain Injury in Mice.
Yasunaga M, Takata F, Iwao T, Mizoguchi J, Tajima N, Dohgu S
International journal of molecular sciences 2025 Mar 25;26(7)
International journal of molecular sciences 2025 Mar 25;26(7)
Autophagosomes anchor an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
Segura-Roman A, Citron YR, Shin M, Sindoni N, Maya-Romero A, Rapp S, Goul C, Mancias JD, Zoncu R
The EMBO journal 2025 Jun;44(11):3150-3179
The EMBO journal 2025 Jun;44(11):3150-3179
Suppression of KDM5C mitigates the symptoms of Alzheimer's disease by up-regulating BDNF expression.
Han J, Hong R, Cao C, Zhang L, Sun A, Li Y, Chi Y, Zhang L, Yang Y, Qu X
Neurochemistry international 2025 Jun;186:105975
Neurochemistry international 2025 Jun;186:105975
Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration.
Xu J, Hörner M, Nagel M, Perhat P, Korneck M, Noß M, Hauser S, Schoels L, Admard J, Casadei N, Schuele R
Open biology 2025 Jun;15(6):250101
Open biology 2025 Jun;15(6):250101
Novel strategy to target glioblastoma-initiating cells using a braintropic adeno-associated virus carrying a miR-dependent genome-editing system.
Wang Z, Zou P, Chen Z, Hou J, Son YL, Yamashita D, Kondo T
British journal of cancer 2025 Jun;132(12):1100-1109
British journal of cancer 2025 Jun;132(12):1100-1109
The Epigenetic Reader PHF23 Is Required for Embryonic Neurogenesis.
Wen Y, He P, Huang Z, Ding C, Zhang T, Zhang L, Zheng J, Chen M, Chen C, Liu Y, Wang Y, Zhang Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Jun 25;45(26)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Jun 25;45(26)
Serum amyloid A drive microglia shift to a resolving phenotype through Nrf2.
Li Q, Huang Y, Ban T, Chen K, Zhen X, Dai Q, Zhang G
Neuropharmacology 2025 Jun 1;270:110374
Neuropharmacology 2025 Jun 1;270:110374
Transcranial iTBS Combined With Trans-Spinal iTBS Targeting PDE1A/cAMP/PKA Axis Regulates Neural Regeneration After Spinal Cord Injury.
Fu Y, Wang X, Chen X, Wu S
CNS neuroscience & therapeutics 2025 Jul;31(7):e70525
CNS neuroscience & therapeutics 2025 Jul;31(7):e70525
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy.
Chen ZP, Zhao X, Wang S, Cai R, Liu Q, Ye H, Wang MJ, Peng SY, Xue WX, Zhang YX, Li W, Tang H, Huang T, Zhang Q, Li L, Gao L, Zhou H, Hang C, Zhu JN, Li X, Liu X, Cong Q, Yan C
Nature neuroscience 2025 Jul;28(7):1404-1417
Nature neuroscience 2025 Jul;28(7):1404-1417
Refined qingkailing attenuates reactive astrocytes and glial scar formation after ischemia stroke via the EGFR/PLCγ pathway.
Ren ZL, Zhang CX, Zheng YX, Chen CA, Dan-Chen, Lan X, Yan X, Liu Y, He YH, Cheng JL, Han JH, Wang QG, Wang XQ, Cheng FF, Li CX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156696
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156696
Neuronal FGF13 Inhibits Mitochondria-Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease.
Song N, Wang X, Ha L, Hu L, Mei S, Liang Y, Zhao Y, Yang X, Zhang Q, Zhou Y, Ding J, Liu Y, Zhou Q, Han F, Hu G, Lu M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2503579
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2503579
The expression profile of type 1 equilibrative nucleoside transporter in aged C57BL/6J mouse brain.
Zhang XY, Ma Z, Jin YH, Long Z, Tang Q, He G, Jia YF
Acta biochimica et biophysica Sinica 2025 Jul 28;58(4):780-91
Acta biochimica et biophysica Sinica 2025 Jul 28;58(4):780-91
Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a.
Shen J, Gao L, Gao J, Wang L, Yan D, Wang Y, Meng J, Li H, Chen D, Wu J
Biomolecules 2025 Jul 27;15(8)
Biomolecules 2025 Jul 27;15(8)
Ethyl Acetate Fraction of Zanthoxylum bungeanum Ameliorates Cognitive Deficit by Facilitating the PHGDH-Dependent Astrocyte-Neuron Serine Shuttle in Aging Mice.
Zhao M, Zeng L, Zhou Y, Yang C, Sheng R, Liu X, Wen W, Yang S, Zhang S, Xu S
Journal of agricultural and food chemistry 2025 Jul 2;73(26):16301-16316
Journal of agricultural and food chemistry 2025 Jul 2;73(26):16301-16316
Deficiency of Rab26 causes behavioral defects in mice through impaired trafficking of serotonin (5-HT) transporter.
Ren Y, Wang Z, Wei Z, Zhuang R, Zhang Y, Liu X, Jiang C, Liu X, Yun Y, Li Y, Hong W, Wang T
iScience 2025 Jul 18;28(7):112931
iScience 2025 Jul 18;28(7):112931
The Upregulation of L1CAM by SVHRSP Mitigates Neuron Damage, Spontaneous Seizures, and Cognitive Dysfunction in a Kainic Acid-Induced Rat Model of Epilepsy.
Li Z, Ge B, Li H, Huang C, Ji Y, Schachner M, Yin S, Li S, Zhao J
Biomolecules 2025 Jul 17;15(7)
Biomolecules 2025 Jul 17;15(7)
THSG counteracts microglial glycolytic reprogramming and neuronal necroptosis both in vivo and in vitro under conditions of neuroinflammation.
Guo Z, Zhong S, Bai J, Lang X, Cao M, Hu Y, Qin X, Sun Y
Scientific reports 2025 Jul 1;15(1):21721
Scientific reports 2025 Jul 1;15(1):21721
Bioactive Peptide Hydrogel Scaffold with High Fluidity, Thermosensitivity, and Neurotropism in 3D Spatial Structure for Promoted Repair of Spinal Cord Injury.
Sun Z, Luan X, Sun Z, Li D, Hu H, Xue Q, Liu B, Yu Q, Wei G, Zhang X, Xi Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(2):e2406990
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(2):e2406990
BIN1 deficiency enhances ULK3-dependent autophagic flux and reduces dendritic size in mouse hippocampal neurons.
Jin Y, Zhao L, Zhang Y, Chen T, Shi H, Sun H, Ding S, Chen S, Cao H, Zhang G, Li Q, Gao J, Xiao M, Sheng C
Autophagy 2025 Jan;21(1):223-242
Autophagy 2025 Jan;21(1):223-242
The important role of the Wnt/β-catenin signaling pathway in small molecules mediated gingival mesenchymal stem cells transdifferentiate into neuron-like cells.
Liang Q, Zhang C, Lv P, Huang Y, Zhao H, Jiang S, Xu W
Archives of oral biology 2025 Jan;169:106115
Archives of oral biology 2025 Jan;169:106115
Targeting of retrovirus-derived Rtl8a/8b causes late-onset obesity, reduced social response and increased apathy-like behaviour.
Fujioka Y, Shiura H, Ishii M, Ono R, Endo T, Kiyonari H, Hirate Y, Ito H, Kanai-Azuma M, Kohda T, Kaneko-Ishino T, Ishino F
Open biology 2025 Jan;15(1):240279
Open biology 2025 Jan;15(1):240279
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Chi X, Yin S, Sun Y, Kou L, Zou W, Wang Y, Jin Z, Wang T, Xia Y
Brain, behavior, and immunity 2025 Jan;123:229-243
Brain, behavior, and immunity 2025 Jan;123:229-243
Protosequences in brain organoids model intrinsic brain states Authors.
van der Molen T, Spaeth A, Chini M, Hernandez S, Kaurala GA, Schweiger HE, Duncan C, McKenna S, Geng J, Lim M, Bartram J, Dendukuri A, Zhang Z, Gonzalez-Ferrer J, Bhaskaran-Nair K, Blauvelt LJ, Harder CRK, Petzold LR, Alam El Din DM, Laird J, Schenke M, Smirnova L, Colquitt BM, Mostajo-Radji MA, Hansma PK, Teodorescu M, Hierlemann A, Hengen KB, Hanganu-Opatz IL, Kosik KS, Sharf T
bioRxiv : the preprint server for biology 2025 Jan 8;
bioRxiv : the preprint server for biology 2025 Jan 8;
Altered ATP13A2/PARK9 Levels Influence α-Synuclein Accumulation in Neurons via Phagocytosis and Secretion in Glial Cells.
Tsunemi T, Ishiguro Y, Yoroisaka A, Feng D, Hattori N
Cells 2025 Jan 22;14(3)
Cells 2025 Jan 22;14(3)
MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons.
Sharma B, Rodarte D, Goyal G, Rodriguez S, Kumar S
bioRxiv : the preprint server for biology 2025 Jan 13;
bioRxiv : the preprint server for biology 2025 Jan 13;
The sigma-1 receptor-TAMM41 axis modulates neuroinflammation and attenuates memory impairment during the latent period of epileptogenesis.
Ji J, Gao C, Wang Q, Jia X, Tian H, Wei Y, Liu Z, Wang Y, Guo L
Animal models and experimental medicine 2025 Feb;8(2):197-208
Animal models and experimental medicine 2025 Feb;8(2):197-208
CAMK2G Promotes Neuronal Differentiation and Inhibits Migration in Neuroblastoma.
Ma Y, He C, Lin W, Wang J, Xu C, Pan D, Wang Z, Yao W, Dong R, Jia D, Li K
Journal of pediatric surgery 2025 Feb;60(2):161679
Journal of pediatric surgery 2025 Feb;60(2):161679
Polyphenol Mediated Assembly: Tailored Nano-Dredger Unblocks Axonal Autophagosomes Retrograde Transport Traffic Jam for Accelerated Alzheimer's Waste Clearance.
Meng R, Li Y, Yang X, Cheng Y, Xu M, Zhou L, Wu C, Yu S, Huang W, Wang T, Zhang Q
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2413614
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2413614
The gut-brain axis underlying hepatic encephalopathy in liver cirrhosis.
He X, Hu M, Xu Y, Xia F, Tan Y, Wang Y, Xiang H, Wu H, Ji T, Xu Q, Wang L, Huang Z, Sun M, Wan Y, Cui P, Liang S, Pan Y, Xiao S, He Y, Song R, Yan J, Quan X, Wei Y, Hong C, Liao W, Li F, El-Omar E, Chen J, Qi X, Gao J, Zhou H
Nature medicine 2025 Feb;31(2):627-638
Nature medicine 2025 Feb;31(2):627-638
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
Zhang G, Peng Q, Guo X, Pan L, Xiong M, Zhang X, Dai L, Zhang Z, Xiao T, He J, Liu M, Ke W, Zhang Z
Aging cell 2025 Feb;24(2):e14396
Aging cell 2025 Feb;24(2):e14396
The cholesterol 24-hydroxylase CYP46A1 promotes α-synuclein pathology in Parkinson's disease.
Dai L, Wang J, Meng L, Zhang X, Xiao T, Deng M, Chen G, Xiong J, Ke W, Hong Z, Bu L, Zhang Z
PLoS biology 2025 Feb;23(2):e3002974
PLoS biology 2025 Feb;23(2):e3002974
PLGA scaffold combined with MSCs transplantation improved neural function and brain tissue structure in rats with traumatic brain injury.
Xu N, Sun Z, Guan W, Liu Y, Gao Y, Yang C
Brain research bulletin 2025 Feb;221:111216
Brain research bulletin 2025 Feb;221:111216
Microglia Process α-Synuclein Fibrils and Enhance their Pathogenicity in a TREM2-Dependent Manner.
Xiong M, Xia D, Yu H, Meng L, Zhang X, Chen J, Tian Y, Yuan X, Niu X, Nie S, Zhang Z, Liu C, Chen Q, Ye K, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2413451
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2413451
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Yang W, Li Y, Tang Y, Tao Z, Yu M, Sun C, Ye Y, Xu B, Zhao X, Zhang Y, Lu X
Stem cell research & therapy 2025 Feb 28;16(1):100
Stem cell research & therapy 2025 Feb 28;16(1):100
Urolithin A alleviates NLRP3 inflammasome activation and pyroptosis by promoting microglial mitophagy following spinal cord injury.
Chen K, Ying J, Zhu J, Chen L, Liu R, Jing M, Wang Y, Zhou K, Wu L, Wu C, Xiao J, Ni W
International immunopharmacology 2025 Feb 20;148:114057
International immunopharmacology 2025 Feb 20;148:114057
Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate.
Thayer JA, Petersen JD, Huang X, Hawrot J, Ramos DM, Sekine S, Li Y, Ward ME, Narendra DP
bioRxiv : the preprint server for biology 2025 Feb 20;
bioRxiv : the preprint server for biology 2025 Feb 20;
Ageing-associated gut dysbiosis deteriorates mouse cognition.
Ju H, Zhou Y, Wei W, Hu Y, Fang H, Chen Z, Sun X, Shi Y, Fang H
Acta biochimica et biophysica Sinica 2025 Feb 13;57(8):1234-1243
Acta biochimica et biophysica Sinica 2025 Feb 13;57(8):1234-1243
Intraocular vasculature formation precedes extraocular vasculature penetration of mouse eyes.
Imanishi S, Tomita Y, Negishi K, Tsubota K, Kurihara T
Developmental biology 2025 Dec;528:152-162
Developmental biology 2025 Dec;528:152-162
PPP2/PP2A-mediated dephosphorylation of LC3B links PINK1-PRKN/Parkin-mediated mitophagy to SCA12 pathogenesis.
Li N, Hou H, Su D, Yang B, Ni R, Ma G, Sun S, Ma Q, Peng Q, Chen S, Tam KY, Wang H, Ying Z
Autophagy 2025 Dec;21(12):3182-3194
Autophagy 2025 Dec;21(12):3182-3194
Melatonin improves synaptic morphological plasticity of adolescent male rats after perinatal BDE-209 exposure via SIRT1-mediated LIMK1 and CREB signaling.
Gao J, Shen J, Gao L, Yan D, Wang Y, Meng J, Chen D, Li H, Wu J
Neurotoxicology 2025 Dec;111:103331
Neurotoxicology 2025 Dec;111:103331
Cholestanol promotes tau pathology in a mouse model of tauopathy.
Yu T, Li Y, Li S, Nie S, Feng H, Zhang Z, Meng L
Cellular and molecular life sciences : CMLS 2025 Dec 24;83(1):5
Cellular and molecular life sciences : CMLS 2025 Dec 24;83(1):5
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
Li Y, Yang W, Tang Y, Du S, Ye Y, Xu B, Shi W, Zhao X, Lu X
Neurochemical research 2025 Dec 20;51(1):20
Neurochemical research 2025 Dec 20;51(1):20
From Microbiota to Metabolomics: How Corylus heterophylla Fisch. Male Flower Extract Shields Mice from Cognitive Decline.
Lu W, Li Y, Liao X, Hu H, Zhang B, Liang L, Gao H
Nutrients 2025 Dec 18;17(24)
Nutrients 2025 Dec 18;17(24)
Inhibiting MARS attenuates hyperhomocysteinemia-associated neurodegeneration in Parkinson's disease.
Guo T, Su D, Huang J, Zhao G, Fang X, Yu T, Sun S, Bao A, Bu L, Zhang Z
Neuropharmacology 2025 Dec 15;281:110685
Neuropharmacology 2025 Dec 15;281:110685
Galectin-9 activates microglial asparagine endopeptidase and promotes α-synuclein pathology in Parkinson's disease.
Peng Q, Zhang G, Guo X, Xu X, Li Y, Pan L, Meng L, Xiong J, Li S, Zhang Z
Cell death and differentiation 2025 Dec 14;
Cell death and differentiation 2025 Dec 14;
Astragaloside IV improves cognitive impairment in diabetes by inhibiting calpain-1/NLRP3 mediated microglial activation.
Wang X, Jiang H, Wang H, Zhao C, Ba X
International immunopharmacology 2025 Dec 10;167:115682
International immunopharmacology 2025 Dec 10;167:115682
Nerve-to-cancer transfer of mitochondria during cancer metastasis.
Hoover G, Gilbert S, Curley O, Obellianne C, Lin MT, Hixson W, Pierce TW, Andrews JF, Alexeyev MF, Ding Y, Bu P, Behbod F, Medina D, Chang JT, Ayala G, Grelet S
Nature 2025 Aug;644(8075):252-262
Nature 2025 Aug;644(8075):252-262
Charting the spatial transcriptome of the human cerebral cortex at single-cell resolution.
Wei S, Luo M, Wang P, Chen R, Jin X, Xu C, Li C, Lin X, Xu Z, Liu H, Cheng R, Yang W, Cai Y, Xue G, Huang P, Liu Z, Sun H, Xu J, Jiang Q
Nature communications 2025 Aug 19;16(1):7702
Nature communications 2025 Aug 19;16(1):7702
Antisense oligonucleotide depletion of CCDC146 is a broad-spectrum therapeutic strategy for ALS.
Zhang S, Moll T, Rubin-Sigler J, Tu S, Li S, Yuan E, Liu M, King M, Alhathli E, Treanor C, Twelvetrees A, Weinreich M, Bonsall S, Harvey C, Gornall S, Shaw A, Ganssauge J, Bhinge A, Souza CDS, Ferraiuolo L, Hornstein E, Shalem O, Avila A, Shelkovnikova T, van Dijk CH, Timpanaro IS, Kenna KP, Zeng J, van Damme P, Tsao PS, Shaw PJ, Ichida JK, Cooper-Knock J, Snyder MP
medRxiv : the preprint server for health sciences 2025 Aug 19;
medRxiv : the preprint server for health sciences 2025 Aug 19;
Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure.
Wang Y, Cheng Y, Sun H, Wang Z, Chen N, Shi C, Liu H, Yang J, Xu Y
Scientific reports 2025 Apr 9;15(1):12106
Scientific reports 2025 Apr 9;15(1):12106
Fate plasticity of interneuron specification.
Mostajo-Radji MA, Leon WRM, Breevoort A, Gonzalez-Ferrer J, Schweiger HE, Lehrer J, Zhou L, Schmitz MT, Perez Y, Mukhtar T, Robbins A, Chu J, Andrews MG, Sullivan FN, Tejera D, Choy EC, Paredes MF, Teodorescu M, Kriegstein AR, Alvarez-Buylla A, Pollen AA
iScience 2025 Apr 18;28(4):112295
iScience 2025 Apr 18;28(4):112295
Luteolin attenuates cadmium neurotoxicity by suppressing glial inflammation and supporting neuronal survival.
Ma HY, Wang J, Wang J, Guo Z, Qin XY, Lan R, Hu Y
International immunopharmacology 2025 Apr 16;152:114406
International immunopharmacology 2025 Apr 16;152:114406
Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson's disease-like neurodegeneration.
Denis HL, de Rus Jacquet A, Alpaugh M, Panisset M, Barker RA, Boilard É, Cicchetti F
Fluids and barriers of the CNS 2025 Apr 14;22(1):38
Fluids and barriers of the CNS 2025 Apr 14;22(1):38
VEGF secreted by human dental pulp stem cell promotes spinal cord injury repair by inhibiting microglial pyroptosis through the PI3K/AKT pathway.
Zhang X, Liu T, Ma Z, Li G, Ding N, Wang Z, Guan Y, Zhang Y, Liu L, Chen X
Journal of translational medicine 2025 Apr 12;23(1):437
Journal of translational medicine 2025 Apr 12;23(1):437
In vitro susceptibility of differentiated SH-SY5Y human neuroblastoma cells to herpes simplex virus type 1 and Japanese encephalitis virus infection.
Ferdous J, Makino H, Masatani T, Fujimoto Y, Naitou K, Shiraishi M
The Journal of veterinary medical science 2025 Apr 1;87(4):426-430
The Journal of veterinary medical science 2025 Apr 1;87(4):426-430
The Effect of Differentiation of Human Dental Pulp Stem Cells to Glial Cells on the Sensory Nerves of the Dental Pulp.
Liu Y, Zou Y, Liu X, Wang Y, Sun J, Yuan C, Wang P
International journal of dentistry 2024;2024:3746794
International journal of dentistry 2024;2024:3746794
Mitochondria-Rich Microvesicles Alleviate CNI ED by Transferring Mitochondria and Suppressing Local Ferroptosis.
Liang Z, Chen Z, Zhang C, Chen C, Yang W, Zhang Y, Wei H
International journal of nanomedicine 2024;19:11745-11765
International journal of nanomedicine 2024;19:11745-11765
Perioperative enriched environment attenuates postoperative cognitive dysfunction by upregulating microglia TREM2 via PI3K/Akt pathway in mouse model of ischemic stroke.
Yao Y, Hu L, Li D, Wang Y, Pan J, Fan D
Frontiers in neuroscience 2024;18:1520710
Frontiers in neuroscience 2024;18:1520710
Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis.
Wang X, Lin X, Chen Z, Long H, Zhou X, Lei S, Liu J, Dong H, Liu F, Hu H, Guo C
Frontiers in neuroscience 2024;18:1491343
Frontiers in neuroscience 2024;18:1491343
Neuroprotective effects of ellorarxine in neuronal models of degeneration.
Kouchmeshky A, Whiting A, McCaffery P
Frontiers in neuroscience 2024;18:1422294
Frontiers in neuroscience 2024;18:1422294
Single-cell RNA-sequencing analysis reveals α-syn induced astrocyte-neuron crosstalk-mediated neurotoxicity.
Li K, Ling H, Huang W, Luo W, Gu C, Tao B, Xie Q, Qiu P
International immunopharmacology 2024 Sep 30;139:112676
International immunopharmacology 2024 Sep 30;139:112676
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.
Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
Cell metabolism 2024 Sep 3;36(9):2054-2068.e14
SOLID: minimizing tissue distortion for brain-wide profiling of diverse architectures.
Zhu J, Liu X, Liu Z, Deng Y, Xu J, Liu K, Zhang R, Meng X, Fei P, Yu T, Zhu D
Nature communications 2024 Sep 27;15(1):8303
Nature communications 2024 Sep 27;15(1):8303
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Liu W, Zhong X, Yi Y, Xie L, Zhou W, Cao W, Chen L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Thy1-ApoE4/C/EBPβ double transgenic mice act as a sporadic model with Alzheimer's disease.
Qian Z, Wang Z, Li B, Meng X, Kuang Z, Li Y, Yang Y, Ye K
Molecular psychiatry 2024 Oct;29(10):3040-3055
Molecular psychiatry 2024 Oct;29(10):3040-3055
Wnt/Ca(2+) pathway inhibits neural differentiation of human dental pulp stem cells in vitro.
Wang SH, Wang SR, Luan NN, Sun XQ, Guo YR, Yan YB, Liang SX
Journal of dental sciences 2024 Oct;19(4):2090-2099
Journal of dental sciences 2024 Oct;19(4):2090-2099
IFN-β contributes to astrocyte activation in the brain following coronavirus PHEV infection independent on peripheral immunity.
Shi J, Jia Q, Yu Y, Zhang J, Li Z, He W
Veterinary microbiology 2024 Nov;298:110280
Veterinary microbiology 2024 Nov;298:110280
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway.
Tang Y, Dong MH, Pang XW, Zhang H, Chu YH, Zhou LQ, Yang S, Zhang LY, You YF, Zhu LF, Wang W, Qin C, Tian DS
Journal of neuroinflammation 2024 Nov 8;21(1):292
Journal of neuroinflammation 2024 Nov 8;21(1):292
Schwann cell-secreted frizzled-related protein 1 dictates neuroinflammation and peripheral nerve degeneration after neurotrauma.
Yao X, Kong L, Qiao Y, Brand D, Li J, Yan Z, Zheng SG, Qian Y, Fan C
Cell reports. Medicine 2024 Nov 19;5(11):101791
Cell reports. Medicine 2024 Nov 19;5(11):101791
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells.
Ferdous J, Naitou K, Shiraishi M
The Journal of veterinary medical science 2024 Nov 1;86(11):1136-1144
The Journal of veterinary medical science 2024 Nov 1;86(11):1136-1144
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
Cao J, Yu X, Liu J, Fu J, Wang B, Wu C, Zhang S, Chen H, Wang Z, Xu Y, Sui T, Chang J, Cao X
Neural regeneration research 2024 Nov 1;19(11):2499-2512
Neural regeneration research 2024 Nov 1;19(11):2499-2512
PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model.
Yang J, Wang Y, Xia Y, Ren Y, Wang Z, Meng X, Li S, Liu X, Shao J
Neurochemical research 2024 May;49(5):1226-1238
Neurochemical research 2024 May;49(5):1226-1238
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models.
He Y, Li R, Yu Y, Huang C, Xu Z, Wang T, Chen M, Huang H, Qi Z
Neurochemistry international 2024 May;175:105700
Neurochemistry international 2024 May;175:105700
ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2-BECN1 interaction.
Xu S, Ma Q, Shen J, Li N, Sun S, Wang N, Chen Y, Dong C, Tam KY, Prehn JHM, Wang H, Ying Z
Acta pharmaceutica Sinica. B 2024 May;14(5):2026-2038
Acta pharmaceutica Sinica. B 2024 May;14(5):2026-2038
Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8(+) T cells in cerebral malaria.
Wang Y, Shen Y, Liang J, Wang S, Huang Y, Zhu Q, Zhang X, Yu K, Tong G, Yang C, Li Y, Wang J, Zhao Y
Journal of neuroinflammation 2024 May 7;21(1):119
Journal of neuroinflammation 2024 May 7;21(1):119
Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus.
Song Y, Jiang W, Afridi SK, Wang T, Zhu F, Xu H, Nazir FH, Liu C, Wang Y, Long Y, Huang YA, Qiu W, Tang C
Cell reports 2024 May 28;43(5):114226
Cell reports 2024 May 28;43(5):114226
Wybutosine hypomodification of tRNAphe activates HERVK and impairs neuronal differentiation.
Sun C, Guo R, Ye X, Tang S, Chen M, Zhou P, Yang M, Liao C, Li H, Lin B, Zang C, Qi Y, Han D, Sun Y, Li N, Zhu D, Xu K, Hu H
iScience 2024 May 17;27(5):109748
iScience 2024 May 17;27(5):109748
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Hou B, Yin J, Liu S, Guo J, Zhang B, Zhang Z, Yang L, Tan X, Long Y, Feng S, Zhou J, Wu Y, Wang X, Han S, Wang Z, He X
Molecular neurobiology 2024 Mar;61(3):1318-1330
Molecular neurobiology 2024 Mar;61(3):1318-1330
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
Zhang Y, Li S, Li L, Huang H, Fu Z, Hua Z
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
Disrupting PIAS3-mediated SUMOylation of MLK3 ameliorates poststroke neuronal damage and deficits in cognitive and sensorimotor behaviors.
Jiang Y, Hu L, Wang B, Zhang B, Shao M, Meng L, Xu Y, Chen R, Li M, Du C
Cellular and molecular life sciences : CMLS 2024 Mar 8;81(1):119
Cellular and molecular life sciences : CMLS 2024 Mar 8;81(1):119
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Li XY, Yin X, Lu JJ, Li QR, Xing WQ, Han Q, Ji H, Li SZ, Yang HM, Guo JR, Wang ZQ, Xu B
Cells 2024 Mar 25;13(7)
Cells 2024 Mar 25;13(7)
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Lu Y, Liu S, Wang P, Guo X, Qin Z, Hou H, Tao T
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Protein expression of nucleolar protein 12 in the retina and its implication in protection of retina from UV irradiation damage.
Liu J, Tan X, Li L, Cao L, Zhou Y, Li H, Peng T
Cell death discovery 2024 Mar 11;10(1):130
Cell death discovery 2024 Mar 11;10(1):130
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury.
Huang Z, Feng Y, Zhang Y, Ma X, Zong X, Jordan JD, Zhang Q
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:40-50
Translational research : the journal of laboratory and clinical medicine 2024 Jun;268:40-50
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Zhang X, Li G, Chen H, Nie XW, Bian JS
Free radical biology & medicine 2024 Jun;218:190-204
Free radical biology & medicine 2024 Jun;218:190-204
CircRNA CDR1as affects functional repair after spinal cord injury and regulates fibrosis through the SMAD pathway.
Wang W, Liu C, He D, Shi G, Song P, Zhang B, Li T, Wei J, Jiang Y, Ma L
Pharmacological research 2024 Jun;204:107189
Pharmacological research 2024 Jun;204:107189
Effects of a novel regimen of repetitive transcranial magnetic stimulation (rTMS) on neural remodeling and motor function in adult male mice with ischemic stroke.
Peipei W, Yu D, Xiaoyan L, Yunxia L, Liuming L, Tongbin C, Shaoping L
Journal of neuroscience research 2024 Jun;102(6):e25358
Journal of neuroscience research 2024 Jun;102(6):e25358
Homozygosity for a Rare Plec Variant Suggests a Contributory Role in Congenital Insensitivity to Pain.
Kantaputra P, Daroontum T, Kitiyamas K, Piyakhunakorn P, Kawasaki K, Sathienkijkanchai A, Wasant P, Vatanavicharn N, Yasanga T, Kaewgahya M, Tongsima S, Cox TC, Arold ST, Ohazama A, Ngamphiw C
International journal of molecular sciences 2024 Jun 8;25(12)
International journal of molecular sciences 2024 Jun 8;25(12)
BCI Improves Alcohol-Induced Cognitive and Emotional Impairments by Restoring pERK-BDNF.
Wang S, Zhang X, Zhao Y, Lv H, Li P, Zhang Z, Qiao X
Journal of molecular neuroscience : MN 2024 Jun 18;74(3):59
Journal of molecular neuroscience : MN 2024 Jun 18;74(3):59
FMOD Alleviates Depression-Like Behaviors by Targeting the PI3K/AKT/mTOR Signaling After Traumatic Brain Injury.
Huang X, Zhu Z, Du M, Wu C, Fu J, Zhang J, Tan W, Wu B, Liu L, Liao ZB
Neuromolecular medicine 2024 Jun 12;26(1):24
Neuromolecular medicine 2024 Jun 12;26(1):24
Gliclazide Ameliorates Neuronal Injury by Attenuating Oxidative Stress in D-gal-Induced Senescent Cells and Aging Mice.
Wu DP, Yi W, Zhao YD, Wei YS, Liu LL, Yan QQ, Yu C, Liu JY, Zhu XX, Zhong ZG, Huang JL
Molecular neurobiology 2024 Jul;61(7):4391-4401
Molecular neurobiology 2024 Jul;61(7):4391-4401
A Synthetic Steroid 5α-Androst-3β, 5, 6β-triol Alleviates Radiation-Induced Brain Injury in Mice via Inhibiting GBP5/NF-κB/NLRP3 Signal Axis.
Zhong K, Liu K, Song Y, Chen S, Hu X, Xue R, Ma X, Li S, Yang J, Deng Z, Zhu X, Yuan M, Huang Y, Yin W, Chen Y, Tang Y, Shi Z
Molecular neurobiology 2024 Jul;61(7):4074-4089
Molecular neurobiology 2024 Jul;61(7):4074-4089
The marine-derived compound TAG alleviates Parkinson's disease by restoring RUBCN-mediated lipid metabolism homeostasis.
Yang P, Liu Y, Tong ZW, Huang QH, Xie XH, Mao SY, Ding JH, Lu M, Tan RX, Hu G
Acta pharmacologica Sinica 2024 Jul;45(7):1366-1380
Acta pharmacologica Sinica 2024 Jul;45(7):1366-1380
PM2.5 triggers tau aggregation in a mouse model of tauopathy.
Liu C, Meng L, Gao Y, Chen J, Zhu M, Xiong M, Xiao T, Gu X, Liu C, Li T, Zhang Z
JCI insight 2024 Jul 22;9(14)
JCI insight 2024 Jul 22;9(14)
Toll-like receptor 4-dependent innate immune responses are mediated by intracrine corticosteroids and activation of glycogen synthase kinase-3β in astrocytes.
Lai W, Huang S, Liu J, Zhou B, Yu Z, Brown J, Hong G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23781
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23781
ERβ activation improves nonylphenol-induced depression and neurotransmitter secretion disruption via the TPH2/5-HT pathway.
Yu J, Zhang Y, Yao H, Zhang Z, Yang X, Zhu W, Xu J
Ecotoxicology and environmental safety 2024 Jul 15;280:116521
Ecotoxicology and environmental safety 2024 Jul 15;280:116521
Methylated urolithin A, mitigates cognitive impairment by inhibiting NLRP3 inflammasome and ameliorating mitochondrial dysfunction in aging mice.
Chen P, Wang Y, Xie J, Lei J, Zhou B
Neuropharmacology 2024 Jul 1;252:109950
Neuropharmacology 2024 Jul 1;252:109950
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
Liang HB, Chen X, Zhao R, Li SJ, Huang PS, Tang YH, Cui GH, Liu JR
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
Mannitol inhibits the proliferation of neural stem cell by a p38 mitogen-activated protein kinase-dependent signaling pathway.
Duan HZ, Zhou X, Hu Q, Liu ML, Wang SH, Zhang J, Jiang XH, Zhang TX, Yu AY
Chinese journal of traumatology = Zhonghua chuang shang za zhi 2024 Jan;27(1):42-52
Chinese journal of traumatology = Zhonghua chuang shang za zhi 2024 Jan;27(1):42-52
A ROS-responsive loaded desferoxamine (DFO) hydrogel system for traumatic brain injury therapy.
Qiu Y, Zeng Y, Zhang C, Lv X, Ling Y, Si Y, Guo T, Ni Y, Zhang J, Xu C, Wang Z, Hu J
Biomedical materials (Bristol, England) 2024 Jan 24;19(2)
Biomedical materials (Bristol, England) 2024 Jan 24;19(2)
Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters.
Park Y, Hernandez S, Hernandez CO, Schweiger HE, Li H, Voitiuk K, Dechiraju H, Hawthorne N, Muzzy EM, Selberg JA, Sullivan FN, Urcuyo R, Salama SR, Aslankoohi E, Knight HJ, Teodorescu M, Mostajo-Radji MA, Rolandi M
Cell reports methods 2024 Jan 22;4(1):100686
Cell reports methods 2024 Jan 22;4(1):100686
Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer.
Zhou L, Du K, Dai Y, Zeng Y, Luo Y, Ren M, Pan W, Liu Y, Zhang L, Zhu R, Feng D, Tian F, Gu C
Journal of translational medicine 2024 Jan 13;22(1):55
Journal of translational medicine 2024 Jan 13;22(1):55
Activation of testosterone-androgen receptor mediates cerebrovascular protection by photobiomodulation treatment in photothrombosis-induced stroke rats.
Feng Y, Huang Z, Ma X, Zong X, Wu CY, Lee RH, Lin HW, Hamblin MR, Zhang Q
CNS neuroscience & therapeutics 2024 Feb;30(2):e14574
CNS neuroscience & therapeutics 2024 Feb;30(2):e14574
Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.
He F, Chen C, Wang Y, Wang S, Lyu S, Jiao J, Huang G, Yang J
Experimental and therapeutic medicine 2024 Feb;27(2):71
Experimental and therapeutic medicine 2024 Feb;27(2):71
Disulfide bridge-targeted metabolome mining unravels an antiparkinsonian peptide.
Tong Z, Xie X, Ge H, Jiao R, Wang T, Wang X, Zhuang W, Hu G, Tan R
Acta pharmaceutica Sinica. B 2024 Feb;14(2):881-892
Acta pharmaceutica Sinica. B 2024 Feb;14(2):881-892
The role of NF-κB signaling pathway in reactive astrocytes among neurodegeneration after methamphetamine exposure by integrated bioinformatics.
Li K, Ling H, Wang X, Xie Q, Gu C, Luo W, Qiu P
Progress in neuro-psychopharmacology & biological psychiatry 2024 Feb 8;129:110909
Progress in neuro-psychopharmacology & biological psychiatry 2024 Feb 8;129:110909
Sulbactam protects neurons against double neurotoxicity of amyloid beta and glutamate load by upregulating glial glutamate transporter 1.
Li L, Li W, Jiang W, Xu R
Cell death discovery 2024 Feb 6;10(1):64
Cell death discovery 2024 Feb 6;10(1):64
Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
Zhang W, Huang J, Shi J
Brain sciences 2024 Feb 28;14(3)
Brain sciences 2024 Feb 28;14(3)
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells.
Dai W, Liu Z, Yan M, Nian X, Hong F, Zhou Z, Wang C, Fu X, Li X, Jiang M, Zhu Y, Huang Q, Lu X, Hou L, Yan N, Wang Q, Hu J, Mo W, Zhang X, Zhang L
Developmental cell 2024 Feb 26;59(4):482-495.e6
Developmental cell 2024 Feb 26;59(4):482-495.e6
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
Wang Z, Bi M, Zhe X, Wang X, Dai B, Han X, Ren B, Liang H, Liu D
Cell death discovery 2024 Feb 22;10(1):95
Cell death discovery 2024 Feb 22;10(1):95
Regulation of TAR DNA binding protein 43 (TDP-43) homeostasis by cytosolic DNA accumulation.
Yang C, Leifer C, Lammerding J, Hu F
The Journal of biological chemistry 2024 Dec;300(12):107999
The Journal of biological chemistry 2024 Dec;300(12):107999
Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats.
Fang Y, Zheng Y, Gao Q, Pang M, Wu Y, Feng X, Tao X, Hu Y, Lin Z, Lin W
Redox report : communications in free radical research 2024 Dec;29(1):2394714
Redox report : communications in free radical research 2024 Dec;29(1):2394714
Lycium barbarum oligosaccharide-derived carbon quantum dots inhibit glial scar formation while promoting neuronal differentiation of neural stem cells.
Shao F, Sun X, Yu Q, Wang K, Sun C, Wang Q, Cao X, Zhang L, Fu P, Yang X, Yu J, Xu X, Deng W
International journal of biological macromolecules 2024 Dec;282(Pt 6):137474
International journal of biological macromolecules 2024 Dec;282(Pt 6):137474
TLR3 Knockdown Attenuates Pressure-Induced Neuronal Damage In Vitro.
Lin L, Lv Z, Zhou C, Zhu T, Hu Y, Sun X, Zhou H, Wang M, Lin Y, Gu G, Wang S, Zhou Y, Han J, Jin G, Hua F
Journal of cellular and molecular medicine 2024 Dec;28(23):e70276
Journal of cellular and molecular medicine 2024 Dec;28(23):e70276
Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion and drug screening.
Ramani A, Pasquini G, Gerkau NJ, Jadhav V, Vinchure OS, Altinisik N, Windoffer H, Muller S, Rothenaigner I, Lin S, Mariappan A, Rathinam D, Mirsaidi A, Goureau O, Ricci-Vitiani L, D'Alessandris QG, Wollnik B, Muotri A, Freifeld L, Jurisch-Yaksi N, Pallini R, Rose CR, Busskamp V, Gabriel E, Hadian K, Gopalakrishnan J
Nature communications 2024 Dec 19;15(1):10703
Nature communications 2024 Dec 19;15(1):10703
The classical D1 dopamine receptor antagonist SCH23390 is a functional sigma-1 receptor allosteric modulator.
Zhang GF, Zhu KL, Li Q, Zhang Y, Waddington JL, Du XD, Zhen XC
Acta pharmacologica Sinica 2024 Aug;45(8):1582-1590
Acta pharmacologica Sinica 2024 Aug;45(8):1582-1590
The Role of KDM2A and H3K36me2 Demethylation in Modulating MAPK Signaling During Neurodevelopment.
Ren Z, Tang H, Zhang W, Guo M, Cui J, Wang H, Xie B, Yu J, Chen Y, Zhang M, Han C, Chu T, Liang Q, Zhao S, Huang Y, He X, Liu K, Liu C, Chen C
Neuroscience bulletin 2024 Aug;40(8):1076-1092
Neuroscience bulletin 2024 Aug;40(8):1076-1092
Evidence of mutant huntingtin and tau-related pathology within neuronal grafts in Huntington's disease cases.
Salem S, Kilgore MD, Anwer M, Maxan A, Child D, Bird TD, Keene CD, Cicchetti F, Latimer C
Neurobiology of disease 2024 Aug;198:106542
Neurobiology of disease 2024 Aug;198:106542
Ginsenoside Rg1 Regulates Immune Microenvironment and Neurological Recovery After Spinal Cord Injury Through MYCBP2 Delivery via Neuronal Cell-Derived Extracellular Vesicles.
Rong Y, Wang J, Hu T, Shi Z, Lang C, Liu W, Cai W, Sun Y, Zhang F, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2402114
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2402114
Autophagosomes coordinate an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling.
Segura-Roman A, Citron YR, Shin M, Sindoni N, Maya-Romero A, Rapp S, Goul C, Mancias JD, Zoncu R
bioRxiv : the preprint server for biology 2024 Aug 6;
bioRxiv : the preprint server for biology 2024 Aug 6;
SARS-CoV-2 Spike Protein S1 Domain Accelerates α-Synuclein Phosphorylation and Aggregation in Cellular Models of Synucleinopathy.
Wang J, Dai L, Deng M, Xiao T, Zhang Z, Zhang Z
Molecular neurobiology 2024 Apr;61(4):2446-2458
Molecular neurobiology 2024 Apr;61(4):2446-2458
GDF1 ameliorates cognitive impairment induced by hearing loss.
Pan L, Li C, Meng L, Zhang G, Zou L, Tian Y, Chen S, Sun Y, Su D, Zhang X, Xiong M, Xiao T, Xia D, Hong Z, Zhang Z
Nature aging 2024 Apr;4(4):568-583
Nature aging 2024 Apr;4(4):568-583
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Age-Related Alterations in Peripheral Immune Landscape with Magnified Impact on Post-Stroke Brain.
Lu J, Li H, Zhang G, Yang F, Zhang X, Ping A, Xu Z, Gu Y, Wang R, Ying D, Liu J, Zhang J, Shi L
Research (Washington, D.C.) 2023;6:0287
Research (Washington, D.C.) 2023;6:0287
Effects of early-life tosufloxacin tosilate hydrate administration on growth rate, neurobehavior, and gut microbiota at adulthood in male mice.
Hasegawa A, Sasaki T, Islam J, Tominaga T, Nochi T, Hara K, Tanemura K
The Journal of toxicological sciences 2023;48(3):149-159
The Journal of toxicological sciences 2023;48(3):149-159
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy.
Xylaki M, Paiva I, Al-Azzani M, Gerhardt E, Jain G, Islam MR, Vasili E, Wassouf Z, Schulze-Hentrich JM, Fischer A, Outeiro TF
Journal of Parkinson's disease 2023;13(2):179-196
Journal of Parkinson's disease 2023;13(2):179-196
Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway.
Wang XH, Zuo ZF, Meng L, Yang Q, Lv P, Zhao LP, Wang XB, Wang YF, Huang Y, Fu C, Liu WQ, Liu XZ, Zheng DY
Psychopharmacology 2023 Sep;240(9):1865-1876
Psychopharmacology 2023 Sep;240(9):1865-1876
Autologous olfactory mucosa mesenchymal stem cells treatment improves the neural network in chronic refractory epilepsy.
Liu ZZ, Huang Y, Hong CG, Wang X, Duan R, Liu JY, He JL, Duan D, Xie H, Lu M
Stem cell research & therapy 2023 Sep 7;14(1):237
Stem cell research & therapy 2023 Sep 7;14(1):237
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Ma Q, Xin J, Peng Q, Li N, Sun S, Hou H, Ma G, Wang N, Zhang L, Tam KY, Dussmann H, Prehn JH, Wang H, Ying Z
EMBO reports 2023 Sep 6;24(9):e55859
EMBO reports 2023 Sep 6;24(9):e55859
Protocol for fine casting, imaging, and analysis of murine vascular networks with VALID.
Zhu J, Liu X, Xu J, Liu Z, Deng Y, Dai J, Yu T, Zhu D
STAR protocols 2023 Sep 15;4(3):102441
STAR protocols 2023 Sep 15;4(3):102441
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
A novel small-molecular CCR5 antagonist promotes neural repair after stroke.
Wu QL, Cui LY, Ma WY, Wang SS, Zhang Z, Feng ZP, Sun HS, Chu SF, He WB, Chen NH
Acta pharmacologica Sinica 2023 Oct;44(10):1935-1947
Acta pharmacologica Sinica 2023 Oct;44(10):1935-1947
Exposure to nonylphenol in early life causes behavioural deficits related with autism spectrum disorders in rats.
You M, Li S, Yan S, Yao D, Wang T, Wang Y
Environment international 2023 Oct;180:108228
Environment international 2023 Oct;180:108228
Focal ischemic stroke modifies microglia-derived exosomal miRNAs: potential role of mir-212-5p in neuronal protection and functional recovery.
Li SS, Wu JJ, Xing XX, Li YL, Ma J, Duan YJ, Zhang JP, Shan CL, Hua XY, Zheng MX, Xu JG
Biological research 2023 Oct 3;56(1):52
Biological research 2023 Oct 3;56(1):52
mNSCs overexpressing Rimkla transplantation facilitates cognitive recovery in a mouse model of traumatic brain injury.
Ji T, Pang Y, Cheng M, Wang R, Chen X, Zhang C, Liu M, Zhang J, Zhong C
iScience 2023 Oct 20;26(10):107913
iScience 2023 Oct 20;26(10):107913
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.
Sun S, Xu Y, Yu N, Zhang M, Wang J, Wan D, Tian Z, Zhu H
Molecular neurobiology 2023 Nov;60(11):6227-6247
Molecular neurobiology 2023 Nov;60(11):6227-6247
Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson's disease pathogenesis.
Basu S, Song M, Adams L, Jeong I, Je G, Guhathakurta S, Jiang J, Boparai N, Dai W, Cardozo-Pelaez F, Tatulian SA, Han KY, Elliott J, Baum J, McLean PJ, Dickson DW, Kim YS
Acta neuropathologica 2023 Nov;146(5):685-705
Acta neuropathologica 2023 Nov;146(5):685-705
Cholestanol accelerates α-synuclein aggregation and spreading by activating asparagine endopeptidase.
Yu T, Nie S, Bu L, Liu M, He J, Niu X, Feng H, Guo J, Tang B, Zhang Z, Ye K, Jiang H, Chen L, Zhang Z
JCI insight 2023 Nov 8;8(21)
JCI insight 2023 Nov 8;8(21)
The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease.
Meng L, Liu C, Li Y, Chen G, Xiong M, Yu T, Pan L, Zhang X, Zhou L, Guo T, Yuan X, Liu C, Zhang Z, Zhang Z
Science advances 2023 Nov 3;9(44):eadj1092
Science advances 2023 Nov 3;9(44):eadj1092
The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy.
Meng L, Liu C, Liu M, Chen J, Liu C, Zhang Z, Chen G, Zhang Z
Cell reports 2023 Nov 28;42(11):113342
Cell reports 2023 Nov 28;42(11):113342
The total alkaloids of Sophora alopecuroides L. improve depression-like behavior in mice via BDNF-mediated AKT/mTOR signaling pathway.
Li J, Zhang M, Pei Y, Yang Q, Zheng L, Wang G, Sun Y, Yang W, Liu L
Journal of ethnopharmacology 2023 Nov 15;316:116723
Journal of ethnopharmacology 2023 Nov 15;316:116723
The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons.
Tollis P, Vitiello E, Migliaccio F, D'Ambra E, Rocchegiani A, Garone MG, Bozzoni I, Rosa A, Carissimo A, Laneve P, Caffarelli E
Cell death & disease 2023 Nov 14;14(11):741
Cell death & disease 2023 Nov 14;14(11):741
Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6.
Pan J, Peng J, Li X, Wang H, Rong X, Peng Y
Molecular neurobiology 2023 May;60(5):2749-2766
Molecular neurobiology 2023 May;60(5):2749-2766
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury.
Rong Y, Wang Z, Tang P, Wang J, Ji C, Chang J, Zhu Y, Ye W, Bai J, Liu W, Yin G, Yu L, Zhou X, Cai W
Bioactive materials 2023 May;23:328-342
Bioactive materials 2023 May;23:328-342
Primary cilia TRP channel regulates hippocampal excitability.
Vien TN, Ta MC, Kimura LF, Onay T, DeCaen PG
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2219686120
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2219686120
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Zhang Q, Yang X, Liu J, Song J, Zhang S, Chen L, Zhang M
Food & function 2023 May 11;14(9):4191-4203
Food & function 2023 May 11;14(9):4191-4203
Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1.
Su JW, Yang P, Xing MM, Chen B, Xie XH, Ding JH, Lu M, Liu Y, Guo YW, Hu G
CNS neuroscience & therapeutics 2023 Mar;29(3):893-906
CNS neuroscience & therapeutics 2023 Mar;29(3):893-906
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Lun J, Li Y, Gao X, Gong Z, Chen X, Zou J, Zhou C, Huang Y, Zhou B, Huang P, Cao H
Journal of neuroinflammation 2023 Mar 30;20(1):87
Journal of neuroinflammation 2023 Mar 30;20(1):87
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
Liu LL, Shannahan J, Zheng W
bioRxiv : the preprint server for biology 2023 Mar 18;
bioRxiv : the preprint server for biology 2023 Mar 18;
Role of miR-219a-5p in regulating NMDAR in nonylphenol-induced synaptic plasticity damage.
Fu N, Yu J, Zhu L, Yang L, Ma L, He J, Yu H, Liu J, Tian Y, Xu J
Ecotoxicology and environmental safety 2023 Mar 1;252:114576
Ecotoxicology and environmental safety 2023 Mar 1;252:114576
Exposure to bisphenol A induces neurotoxicity associated with synaptic and cytoskeletal dysfunction in neuro-2a cells.
Wang S, Ning H, Wang X, Chen L, Hua L, Ren F, Hu D, Li R, Ma Z, Ge Y, Yin Z
Toxicology and industrial health 2023 Jun;39(6):325-335
Toxicology and industrial health 2023 Jun;39(6):325-335
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Overexpression of vascular endothelial growth factor enhances the neuroprotective effects of bone marrow mesenchymal stem cell transplantation in ischemic stroke.
Liu C, Yang ZX, Zhou SQ, Ding D, Hu YT, Yang HN, Han D, Hu SQ, Zong XM
Neural regeneration research 2023 Jun;18(6):1286-1292
Neural regeneration research 2023 Jun;18(6):1286-1292
A whole transcriptome profiling analysis for antidepressant mechanism of Xiaoyaosan mediated synapse loss via BDNF/trkB/PI3K signal axis in CUMS rats.
Meng P, Zhang X, Liu TT, Liu J, Luo Y, Xie MX, Yang H, Fang R, Guo DW, Zhong ZY, Wang YH, Ge JW
BMC complementary medicine and therapies 2023 Jun 15;23(1):198
BMC complementary medicine and therapies 2023 Jun 15;23(1):198
Islet amyloid polypeptide triggers α-synuclein pathology in Parkinson's disease.
Meng L, Li Y, Liu C, Zhang G, Chen J, Xiong M, Pan L, Zhang X, Chen G, Xiong J, Liu C, Xu X, Bu L, Zhang Z, Zhang Z
Progress in neurobiology 2023 Jul;226:102462
Progress in neurobiology 2023 Jul;226:102462
Transient neurogenesis in ischemic cortex from Sox2(+) astrocytes.
Yang JL, Fan H, Fu FF, Guo BL, Huang Y, Sun L, Wang WT, Xing JL, Hu XT, Ding YQ, Zhang K, Hu YZ, Wang YZ
Neural regeneration research 2023 Jul;18(7):1521-1526
Neural regeneration research 2023 Jul;18(7):1521-1526
Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury.
Hu Z, Xuan L, Wu T, Jiang N, Liu X, Chang J, Wang T, Han N, Tian X
International immunopharmacology 2023 Jan;114:109616
International immunopharmacology 2023 Jan;114:109616
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
Sun H, Wang Z, Zhang Q, Chen N, Tang M, Yang Z, Xu Y, Kang J, Wang Y
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
Atmospheric particulate matter impairs cognition by modulating synaptic function via the nose-to-brain route.
Liang C, Jiang Y, Zhang T, Ji Y, Zhang Y, Sun Y, Li S, Qi Y, Wang Y, Cai Y, Lai T, Cui L
The Science of the total environment 2023 Jan 20;857(Pt 3):159600
The Science of the total environment 2023 Jan 20;857(Pt 3):159600
Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells.
Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H
International journal of molecular sciences 2023 Jan 20;24(3)
International journal of molecular sciences 2023 Jan 20;24(3)
Mitochondrial transplantation ameliorates hippocampal damage following status epilepticus.
Jia X, Wang Q, Ji J, Lu W, Liu Z, Tian H, Guo L, Wang Y
Animal models and experimental medicine 2023 Feb;6(1):41-50
Animal models and experimental medicine 2023 Feb;6(1):41-50
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Li B, Lu Y, Wang R, Xu T, Lei X, Jin H, Gao X, Xie Y, Liu X, Zeng J
Neurochemical research 2023 Feb;48(2):519-536
Neurochemical research 2023 Feb;48(2):519-536
Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway.
Li X, Zhou R, Peng H, Peng J, Li Q, Mei M
Brain sciences 2023 Feb 3;13(2)
Brain sciences 2023 Feb 3;13(2)
Cofilin promotes tau pathology in Alzheimer's disease.
Yan M, Tang L, Dai L, Lei C, Xiong M, Zhang X, He M, Tian Y, Xiong J, Ke W, Zhang Z, Zhang C, Deng X, Zhang Z
Cell reports 2023 Feb 28;42(2):112138
Cell reports 2023 Feb 28;42(2):112138
Effects of magnetically targeted iron oxide@polydopamine-labeled human umbilical cord mesenchymal stem cells in cerebral infarction in mice.
Yan J, Liu T, Li Y, Zhang J, Shi B, Zhang F, Hou X, Zhang X, Cui W, Li J, Yao H, Li X, Gao Y, Jiang J
Aging 2023 Feb 28;15(4):1130-1142
Aging 2023 Feb 28;15(4):1130-1142
A versatile vessel casting method for fine mapping of vascular networks using a hydrogel-based lipophilic dye solution.
Zhu J, Liu X, Xu J, Deng Y, Wang P, Liu Z, Yang Q, Li D, Yu T, Zhu D
Cell reports methods 2023 Feb 27;3(2):100407
Cell reports methods 2023 Feb 27;3(2):100407
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Hou JY, Zhou XL, Wang XY, Liang J, Xue Q
Neuroscience 2023 Feb 21;512:59-69
Neuroscience 2023 Feb 21;512:59-69
The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model.
Li Y, Xu J, Guo X, Li Z, Cao L, Liu S, Guo Y, Wang G, Luo Y, Zhang Z, Wei X, Zhao Y, Liu T, Wang X, Xia H, Kuang M, Guo Q, Li J, Chen L, Wang Y, Li Q, Wang F, Liu Q, You F
Genome biology 2023 Feb 1;24(1):20
Genome biology 2023 Feb 1;24(1):20
TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasis.
Ye P, Fang Q, Hu X, Zou W, Huang M, Ke M, Li Y, Liu M, Cai X, Zhang C, Hua N, Al-Sheikh U, Liu X, Yu P, Jiang P, Pan PY, Luo J, Jiang LH, Xu S, Fang EF, Su H, Kang L, Yang W
Progress in neurobiology 2023 Dec;231:102530
Progress in neurobiology 2023 Dec;231:102530
DLP printed hDPSC-loaded GelMA microsphere regenerates dental pulp and repairs spinal cord.
Qian Y, Gong J, Lu K, Hong Y, Zhu Z, Zhang J, Zou Y, Zhou F, Zhang C, Zhou S, Gu T, Sun M, Wang S, He J, Li Y, Lin J, Yuan Y, Ouyang H, Yu M, Wang H
Biomaterials 2023 Aug;299:122137
Biomaterials 2023 Aug;299:122137
NRF2 activation suppresses motor neuron ferroptosis induced by the SOD1(G93A) mutation and exerts neuroprotection in amyotrophic lateral sclerosis.
Yang B, Pan J, Zhang XN, Wang H, He L, Rong X, Li X, Peng Y
Neurobiology of disease 2023 Aug;184:106210
Neurobiology of disease 2023 Aug;184:106210
Human forebrain organoid-based multi-omics analyses of PCCB as a schizophrenia associated gene linked to GABAergic pathways.
Zhang W, Zhang M, Xu Z, Yan H, Wang H, Jiang J, Wan J, Tang B, Liu C, Chen C, Meng Q
Nature communications 2023 Aug 24;14(1):5176
Nature communications 2023 Aug 24;14(1):5176
Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture.
Fu H, Li J, Du P, Jin W, Gao G, Cui D
FEBS letters 2023 Apr;597(7):1007-1040
FEBS letters 2023 Apr;597(7):1007-1040
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10
Developmental cell 2023 Apr 10;58(7):597-615.e10
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer's Disease Models.
Zhang W, Zhang M, Wu Q, Shi J
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
Journal of Alzheimer's disease : JAD 2022;86(1):297-313
Tubulin Isotypes and Posttranslational Modifications in Vascular Dementia and Alzheimer's Disease.
Santiago-Mujika E, Luthi-Carter R, Giorgini F, Mukaetova-Ladinska EB
Journal of Alzheimer's disease reports 2022;6(1):739-748
Journal of Alzheimer's disease reports 2022;6(1):739-748
MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1(G93A) Motor Neuron of Amyotrophic Lateral Sclerosis.
Peng J, Pan J, Mo J, Peng Y
Oxidative medicine and cellular longevity 2022;2022:8217663
Oxidative medicine and cellular longevity 2022;2022:8217663
High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats.
Sun Y, Zhu X, Zhu K, Yu J, Cheng L, Hei M
International journal of medical sciences 2022;19(14):2093-2103
International journal of medical sciences 2022;19(14):2093-2103
Rare KCND3 Loss-of-Function Mutation Associated With the SCA19/22.
Li M, Liu F, Hao X, Fan Y, Li J, Hu Z, Shi J, Fan L, Zhang S, Ma D, Guo M, Xu Y, Shi C
Frontiers in molecular neuroscience 2022;15:919199
Frontiers in molecular neuroscience 2022;15:919199
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Peng Q, Zhang G, Guo X, Dai L, Xiong M, Zhang Z, Chen L, Zhang Z
Frontiers in molecular neuroscience 2022;15:1046992
Frontiers in molecular neuroscience 2022;15:1046992
Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation.
Lang XY, Hu Y, Bai JP, Wang J, Qin XY, Lan R
Frontiers in pharmacology 2022;13:903235
Frontiers in pharmacology 2022;13:903235
DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis.
Yang JY, Shen DY, Wang J, Dai JF, Qin XY, Hu Y, Lan R
Frontiers in pharmacology 2022;13:902796
Frontiers in pharmacology 2022;13:902796
Tandem mass tag-based quantitative proteomic analysis of effects of multiple sevoflurane exposures on the cerebral cortex of neonatal and adult mice.
Feng J, Lin H, Zhao Y, Yang Y, Zhuang X, Yu Y, Yu Y
Frontiers in neurology 2022;13:1056947
Frontiers in neurology 2022;13:1056947
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model.
Lu Y, Zhang J, Zeng F, Wang P, Guo X, Wang H, Qin Z, Tao T
Journal of neuroinflammation 2022 Sep 7;19(1):221
Journal of neuroinflammation 2022 Sep 7;19(1):221
Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury.
Zhang Z, Jiang J, He Y, Cai J, Xie J, Wu M, Xing M, Zhang Z, Chang H, Yu P, Chen S, Yang Y, Shi Z, Liu Q, Sun H, He B, Zeng J, Huang J, Chen J, Li H, Li Y, Lin WJ, Tang Y
Journal of neuroinflammation 2022 Sep 21;19(1):231
Journal of neuroinflammation 2022 Sep 21;19(1):231
Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects.
Liang JH, Alevy J, Akhanov V, Seo R, Massey CA, Jiang D, Zhou J, Sillitoe RV, Noebels JL, Samuel MA
Disease models & mechanisms 2022 Sep 1;15(9)
Disease models & mechanisms 2022 Sep 1;15(9)
GPBAR1 preserves neurite and synapse of dopaminergic neurons via RAD21-OPCML signaling: Role in preventing Parkinson's disease in mouse model and human patients.
Zhang Y, Sun X, Zhang Y, Kang Z, Cai L, Ding J, Lu M, Hu G
Pharmacological research 2022 Oct;184:106459
Pharmacological research 2022 Oct;184:106459
Therapeutic Effect of Biomimetic Scaffold Loaded with Human Amniotic Epithelial Cell-Derived Neural-like Cells for Spinal Cord Injury.
Qiu C, Sun Y, Li J, Xu Y, Zhou J, Qiu C, Zhang S, He Y, Yu L
Bioengineering (Basel, Switzerland) 2022 Oct 9;9(10)
Bioengineering (Basel, Switzerland) 2022 Oct 9;9(10)
Ectosomes and exosomes modulate neuronal spontaneous activity.
Brás IC, Khani MH, Riedel D, Parfentev I, Gerhardt E, van Riesen C, Urlaub H, Gollisch T, Outeiro TF
Journal of proteomics 2022 Oct 30;269:104721
Journal of proteomics 2022 Oct 30;269:104721
Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice.
Li S, Fang Y, Zhang Y, Song M, Zhang X, Ding X, Yao H, Chen M, Sun Y, Ding J, Wang Q, Lu M, Wu G, Hu G
Cell reports 2022 Oct 25;41(4):111532
Cell reports 2022 Oct 25;41(4):111532
Tau accelerates α-synuclein aggregation and spreading in Parkinson's disease.
Pan L, Li C, Meng L, Tian Y, He M, Yuan X, Zhang G, Zhang Z, Xiong J, Chen G, Zhang Z
Brain : a journal of neurology 2022 Oct 21;145(10):3454-3471
Brain : a journal of neurology 2022 Oct 21;145(10):3454-3471
Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia-Reperfusion Injury in Mice.
Sun J, Yuan Q, Guo L, Xiao G, Zhang T, Liang B, Yao R, Zhu Y, Li Y, Hu L
Pharmaceuticals (Basel, Switzerland) 2022 Oct 19;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Oct 19;15(10)
A three-dimensional matrix system containing melatonin and neural stem cells repairs damage from traumatic brain injury in rats.
Fang XY, Zhao DW, Zhang C, Ge HF, Zhang XY, Zhao FC, Jiang YB, Feng H, Hu R
Neural regeneration research 2022 Nov;17(11):2512-2517
Neural regeneration research 2022 Nov;17(11):2512-2517
A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca(2+) Signaling Pathway.
Liu J, Zhang C, Wang J, Huang Y, Shen D, Hu Y, Chu H, Yu X, Zhang L, Ma H
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 28;15(12)
SKF83959 Attenuates Memory Impairment and Depressive-like Behavior during the Latent Period of Epilepsy via Allosteric Activation of the Sigma-1 Receptor.
Guo L, Gao T, Jia X, Gao C, Tian H, Wei Y, Lu W, Liu Z, Wang Y
ACS chemical neuroscience 2022 Nov 16;13(22):3198-3209
ACS chemical neuroscience 2022 Nov 16;13(22):3198-3209
miR-92a-2-5p Regulates the Proliferation and Differentiation of ASD-Derived Neural Progenitor Cells.
Zhuang W, Liu H, He Z, Ju J, Gao Q, Shan Z, Lei L
Current issues in molecular biology 2022 May 24;44(6):2431-2442
Current issues in molecular biology 2022 May 24;44(6):2431-2442
The LPA-CDK5-tau pathway mediates neuronal injury in an in vitro model of ischemia-reperfusion insult.
Wang Y, Zhang J, Huang L, Mo Y, Wang C, Li Y, Zhang Y, Zhang Z
BMC neurology 2022 May 2;22(1):166
BMC neurology 2022 May 2;22(1):166
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Liu MX, Luo L, Fu JH, He JY, Chen MY, He ZJ, Jia J
Experimental neurology 2022 Mar;349:113952
Experimental neurology 2022 Mar;349:113952
Recombinant human erythropoietin protects long-term cultured ageing primary nerve cells by upregulating the PI3K/Akt pathway.
Wang H, Chen M, Gao Z, Gong Y, Yu X, Wu H
Neuroreport 2022 Mar 2;33(4):186-198
Neuroreport 2022 Mar 2;33(4):186-198
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.
Feng T, Luan L, Katz II, Ullah M, Van Deerlin VM, Trojanowski JQ, Lee EB, Hu F
Acta neuropathologica communications 2022 Mar 14;10(1):33
Acta neuropathologica communications 2022 Mar 14;10(1):33
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Shu XM, Hu Y, Fang X, Wang J, Qin XY, Lan R
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jun;71(5-6):615-626
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jun;71(5-6):615-626
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8(+) T cells.
Liang J, Shen Y, Wang Y, Huang Y, Wang J, Zhu Q, Tong G, Yu K, Cao W, Wang Q, Li Y, Zhao Y
Molecular brain 2022 Jun 20;15(1):57
Molecular brain 2022 Jun 20;15(1):57
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
Hu Y, Fang X, Wang J, Ren TT, Zhao YY, Dai JF, Qin XY, Lan R
Neurotoxicology 2022 Jul;91:60-68
Neurotoxicology 2022 Jul;91:60-68
Electroacupuncture treatment improves motor function and neurological outcomes after cerebral ischemia/reperfusion injury.
Li SS, Hua XY, Zheng MX, Wu JJ, Ma ZZ, Xing XX, Ma J, Shan CL, Xu JG
Neural regeneration research 2022 Jul;17(7):1545-1555
Neural regeneration research 2022 Jul;17(7):1545-1555
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
Zhang G, Meng L, Wang Z, Peng Q, Chen G, Xiong J, Zhang Z
Molecular neurodegeneration 2022 Jan 29;17(1):12
Molecular neurodegeneration 2022 Jan 29;17(1):12
Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis.
Li XX, Lang XY, Ren TT, Wang J, Lan R, Qin XY
Journal of ethnopharmacology 2022 Jan 10;282:114606
Journal of ethnopharmacology 2022 Jan 10;282:114606
Exploring the pharmacological mechanism of calculus bovis in cerebral ischaemic stroke using a network pharmacology approach.
Du X, Li C, Zhang S, Sun C, Zhang X, Chen C, Wang X, Cheng F, Wang Q
Journal of ethnopharmacology 2022 Feb 10;284:114507
Journal of ethnopharmacology 2022 Feb 10;284:114507
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Kong X, Shu X, Wang J, Liu D, Ni Y, Zhao W, Wang L, Gao Z, Chen J, Yang B, Guo X, Wang Z
Development (Cambridge, England) 2022 Dec 15;149(24)
Development (Cambridge, England) 2022 Dec 15;149(24)
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer's disease.
Wang XJ, Qi L, Cheng YF, Ji XF, Chi TY, Liu P, Zou LB
Acta pharmacologica Sinica 2022 Aug;43(8):1916-1927
Acta pharmacologica Sinica 2022 Aug;43(8):1916-1927
CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons.
Song G, Ma Y, Gao X, Zhang X, Zhang F, Tian C, Hou J, Liu Z, Zhao Z, Tian Y
Life medicine 2022 Aug;1(1):27-44
Life medicine 2022 Aug;1(1):27-44
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function.
Baron DM, Fenton AR, Saez-Atienzar S, Giampetruzzi A, Sreeram A, Shankaracharya, Keagle PJ, Doocy VR, Smith NJ, Danielson EW, Andresano M, McCormack MC, Garcia J, Bercier V, Van Den Bosch L, Brent JR, Fallini C, Traynor BJ, Holzbaur ELF, Landers JE
Cell reports 2022 Apr 5;39(1):110598
Cell reports 2022 Apr 5;39(1):110598
A functional SNP rs895819 on pre-miR-27a is associated with bipolar disorder by targeting NCAM1.
Yang Y, Lu W, Ning M, Zhou X, Wan X, Mi Q, Yang X, Zhang D, Zhang Y, Jiang B, He L, Liu J, Zou Y
Communications biology 2022 Apr 4;5(1):309
Communications biology 2022 Apr 4;5(1):309
Low-Intensity Ultrasound Causes Direct Excitation of Auditory Cortical Neurons.
Qi X, Lyu K, Meng L, Li C, Zhang H, Niu L, Lin Z, Zheng H, Tang J
Neural plasticity 2021;2021:8855055
Neural plasticity 2021;2021:8855055
Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression.
Zhang D, Shen Q, Wu X, Xing D
Oxidative medicine and cellular longevity 2021;2021:6678276
Oxidative medicine and cellular longevity 2021;2021:6678276
Loss of mitochondrial transcription factor A in neural stem cells leads to immature brain development and triggers the activation of the integral stress response in vivo.
Kuroda R, Tominaga K, Kasashima K, Kuroiwa K, Sakashita E, Hayakawa H, Kouki T, Ohno N, Kawai K, Endo H
PloS one 2021;16(7):e0255355
PloS one 2021;16(7):e0255355
Transgenic Mice Expressing Human α-Synuclein 1-103 Fragment as a Novel Model of Parkinson's Disease.
Tian Y, He M, Pan L, Yuan X, Xiong M, Meng L, Yao Z, Yu Z, Ye K, Zhang Z
Frontiers in aging neuroscience 2021;13:760781
Frontiers in aging neuroscience 2021;13:760781
Rhein Relieves Oxidative Stress in an Aβ(1-42) Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis.
Yin Z, Geng X, Zhang Z, Wang Y, Gao X
Frontiers in pharmacology 2021;12:746711
Frontiers in pharmacology 2021;12:746711
The Role of HSP90α in Methamphetamine/Hyperthermia-Induced Necroptosis in Rat Striatal Neurons.
Liao LS, Lu S, Yan WT, Wang SC, Guo LM, Yang YD, Huang K, Hu XM, Zhang Q, Yan J, Xiong K
Frontiers in pharmacology 2021;12:716394
Frontiers in pharmacology 2021;12:716394
Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.
Chen ML, Hong CG, Yue T, Li HM, Duan R, Hu WB, Cao J, Wang ZX, Chen CY, Hu XK, Wu B, Liu HM, Tan YJ, Liu JH, Luo ZW, Zhang Y, Rao SS, Luo MJ, Yin H, Wang YY, Xia K, Tang SY, Xie H, Liu ZZ
Theranostics 2021;11(5):2395-2409
Theranostics 2021;11(5):2395-2409
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
Fan SR, Ren TT, Yun MY, Lan R, Qin XY
Neurotoxicology 2021 Sep;86:1-9
Neurotoxicology 2021 Sep;86:1-9
Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway.
Yu P, Wang L, Tang F, Guo S, Liao H, Fan C, Yang Q
Life sciences 2021 Sep 1;280:119715
Life sciences 2021 Sep 1;280:119715
Maternal Ethanol Exposure Acutely Elevates Src Family Kinase Activity in the Fetal Cortex.
Wang D, Howell BW, Olson EC
Molecular neurobiology 2021 Oct;58(10):5210-5223
Molecular neurobiology 2021 Oct;58(10):5210-5223
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Jiang GT, Shao L, Kong S, Zeng ML, Cheng JJ, Chen TX, Han S, Yin J, Liu WH, He XH, Liu YM, Gongga L, Peng BW
Neuroscience bulletin 2021 Oct;37(10):1427-1440
Neuroscience bulletin 2021 Oct;37(10):1427-1440
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
Kir6.2 is essential to maintain neurite features by modulating PM20D1-reduced mitochondrial ATP generation.
Song N, Fang Y, Zhu H, Liu J, Jiang S, Sun S, Xu R, Ding J, Hu G, Lu M
Redox biology 2021 Nov;47:102168
Redox biology 2021 Nov;47:102168
Remote Limb Ischemic Postconditioning Protects Against Ischemic Stroke by Promoting Regulatory T Cells Thriving.
Yu HH, Ma XT, Ma X, Chen M, Chu YH, Wu LJ, Wang W, Qin C, Tian DS
Journal of the American Heart Association 2021 Nov 16;10(22):e023077
Journal of the American Heart Association 2021 Nov 16;10(22):e023077
In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury.
Tai W, Wu W, Wang LL, Ni H, Chen C, Yang J, Zang T, Zou Y, Xu XM, Zhang CL
Cell stem cell 2021 May 6;28(5):923-937.e4
Cell stem cell 2021 May 6;28(5):923-937.e4
Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice.
Luong H, Singh S, Patil M, Krishnamurthy P
American journal of physiology. Heart and circulatory physiology 2021 May 1;320(5):H2044-H2057
American journal of physiology. Heart and circulatory physiology 2021 May 1;320(5):H2044-H2057
XQ-1H promotes cerebral angiogenesis via activating PI3K/Akt/GSK3β/β-catenin/VEGF signal in mice exposed to cerebral ischemic injury.
Fei Y, Zhao B, Zhu J, Fang W, Li Y
Life sciences 2021 May 1;272:119234
Life sciences 2021 May 1;272:119234
Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.
Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274
Aging 2021 Mar 26;13(7):10240-10274
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8
Neuron 2021 Mar 17;109(6):957-970.e8
Upregulation of antioxidant and autophagy pathways via NRF2 activation protects spinal cord neurons from ozone damage.
Zhang C, Ma S, Zhao X, Wen B, Sun P, Fu Z
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Thymosin β4 reverses phenotypic polarization of glial cells and cognitive impairment via negative regulation of NF-κB signaling axis in APP/PS1 mice.
Wang M, Feng LR, Li ZL, Ma KG, Chang KW, Chen XL, Yang PB, Ji SF, Ma YB, Han H, Ruganzua JB, Yang WN, Qian YH
Journal of neuroinflammation 2021 Jun 28;18(1):146
Journal of neuroinflammation 2021 Jun 28;18(1):146
Edaravone attenuates H(2)O(2) or glutamate-induced toxicity in hippocampal neurons and improves AlCl(3)/D-galactose induced cognitive impairment in mice.
Wu HT, Yu Y, Li XX, Lang XY, Gu RZ, Fan SR, Fang X, Bai JP, Lan R, Qin XY
Neurotoxicology 2021 Jul;85:68-78
Neurotoxicology 2021 Jul;85:68-78
3D printable Sodium alginate-Matrigel (SA-MA) hydrogel facilitated ectomesenchymal stem cells (EMSCs) neuron differentiation.
Li Y, Cao X, Deng W, Yu Q, Sun C, Ma P, Shao F, Yusif MM, Ge Z, Wang K, Li R, Yu J, Xu X
Journal of biomaterials applications 2021 Jan;35(6):709-719
Journal of biomaterials applications 2021 Jan;35(6):709-719
Defective biosynthesis of ascorbic acid in Sod1-deficient mice results in lethal damage to lung tissue.
Homma T, Takeda Y, Nakano T, Akatsuka S, Kinoshita D, Kurahashi T, Saitoh S, Yamada KI, Miyata S, Asao H, Goto K, Watanabe T, Watanabe M, Toyokuni S, Fujii J
Free radical biology & medicine 2021 Jan;162:255-265
Free radical biology & medicine 2021 Jan;162:255-265
Protection of hUC-MSCs against neuronal complement C3a receptor-mediated NLRP3 activation in CUMS-induced mice.
Li J, Tian S, Wang H, Wang Y, Du C, Fang J, Wang X, Wang Y, Gong Z, Yan B, Wang M
Neuroscience letters 2021 Jan 10;741:135485
Neuroscience letters 2021 Jan 10;741:135485
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
Wang L, Yan M, Li H, Wu S, Ge R, Wong CKC, Silvestrini B, Sun F, Cheng CY
Endocrinology 2021 Jan 1;162(1)
Endocrinology 2021 Jan 1;162(1)
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Shao L, Jiang GT, Yang XL, Zeng ML, Cheng JJ, Kong S, Dong X, Chen TX, Han S, Yin J, Liu WH, He XH, He C, Peng BW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
Effects of the histone acetylase inhibitor C646 on growth and differentiation of adipose-derived stem cells.
Wang Z, Wang X, Bi M, Hu X, Wang Q, Liang H, Liu D
Cell cycle (Georgetown, Tex.) 2021 Feb;20(4):392-405
Cell cycle (Georgetown, Tex.) 2021 Feb;20(4):392-405
EGB761 ameliorates chronic cerebral hypoperfusion-induced cognitive dysfunction and synaptic plasticity impairment.
Yao ZH, Wang J, Yuan JP, Xiao K, Zhang SF, Xie YC, Mei JH
Aging 2021 Feb 3;13(7):9522-9541
Aging 2021 Feb 3;13(7):9522-9541
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Ren TT, Yang JY, Wang J, Fan SR, Lan R, Qin XY
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice.
Ma X, Cheng O, Jiang Q, Yang J, Xiao H, Qiu H
Neuromolecular medicine 2021 Dec;23(4):521-530
Neuromolecular medicine 2021 Dec;23(4):521-530
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.
Han X, Xu T, Fang Q, Zhang H, Yue L, Hu G, Sun L
Redox biology 2021 Aug;44:102010
Redox biology 2021 Aug;44:102010
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2.
Xia Y, Zhang G, Kou L, Yin S, Han C, Hu J, Wan F, Sun Y, Wu J, Li Y, Huang J, Xiong N, Zhang Z, Wang T
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Brain : a journal of neurology 2021 Aug 17;144(7):2024-2037
Qingxin Kaiqiao Fang Inhibits Aβ (25-35)-Induced Apoptosis in Primary Cultured Rat Hippocampal Neuronal Cells via the p38 MAPK Pathway: An Experimental Validation and Network Pharmacology Study.
Wang TQ, Lai XX, Xu LT, Shen Y, Lin JW, Gao SY, Hu HY
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9058135
Evidence-based complementary and alternative medicine : eCAM 2020;2020:9058135
Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation.
Zhang J, Jiang X, Zhang C, Zhong J, Fang X, Li H, Xie F, Huang X, Zhang X, Hu Q, Ge H, Yu A
Stem cells international 2020;2020:4764012
Stem cells international 2020;2020:4764012
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
Chen C, Chencheng Z, Cuiying L, Xiaokun G
Frontiers in cellular neuroscience 2020;14:8
Frontiers in cellular neuroscience 2020;14:8
RNA Binding Protein Motif 3 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Apoptosis Through Promoting Stress Granules Formation in PC12 Cells and Rat Primary Cortical Neurons.
Si W, Li Z, Huang Z, Ye S, Li X, Li Y, Kuang W, Chen D, Zhu M
Frontiers in cellular neuroscience 2020;14:559384
Frontiers in cellular neuroscience 2020;14:559384
Ablation of GSDMD Improves Outcome of Ischemic Stroke Through Blocking Canonical and Non-canonical Inflammasomes Dependent Pyroptosis in Microglia.
Wang K, Sun Z, Ru J, Wang S, Huang L, Ruan L, Lin X, Jin K, Zhuge Q, Yang S
Frontiers in neurology 2020;11:577927
Frontiers in neurology 2020;11:577927
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Yin Z, Hua L, Chen L, Hu D, Li J, An Z, Tian T, Ning H, Ge Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, Zhang J, Jing W, Cong B, Ma C
Brain research bulletin 2020 Sep;162:73-83
Brain research bulletin 2020 Sep;162:73-83
Cofilin 1 promotes the aggregation and cell-to-cell transmission of α-synuclein in Parkinson's disease.
Yan M, Meng L, Dai L, Zhang X, Chen G, Zheng Y, Zha Y, Zeng Y, Zhang Z
Biochemical and biophysical research communications 2020 Sep 3;529(4):1053-1060
Biochemical and biophysical research communications 2020 Sep 3;529(4):1053-1060
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat.
Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, Xue C, Han Q, Wei J, Zhao RC
Aging 2020 Sep 23;12(18):18274-18296
Aging 2020 Sep 23;12(18):18274-18296
Neuron-Derived Estrogen Is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain.
Lu Y, Sareddy GR, Wang J, Zhang Q, Tang FL, Pratap UP, Tekmal RR, Vadlamudi RK, Brann DW
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Sep 16;40(38):7355-7374
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Sep 16;40(38):7355-7374
SARS-CoV-2 targets neurons of 3D human brain organoids.
Ramani A, Müller L, Ostermann PN, Gabriel E, Abida-Islam P, Müller-Schiffmann A, Mariappan A, Goureau O, Gruell H, Walker A, Andrée M, Hauka S, Houwaart T, Dilthey A, Wohlgemuth K, Omran H, Klein F, Wieczorek D, Adams O, Timm J, Korth C, Schaal H, Gopalakrishnan J
The EMBO journal 2020 Oct 15;39(20):e106230
The EMBO journal 2020 Oct 15;39(20):e106230
5-HT(1A)R alleviates Aβ-induced cognitive decline and neuroinflammation through crosstalk with NF-κB pathway in mice.
Wang M, Zong HF, Chang KW, Han H, Yasir Rizvi M, Iffat Neha S, Li ZY, Yang WN, Qian YH
International immunopharmacology 2020 May;82:106354
International immunopharmacology 2020 May;82:106354
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
He X, Yang W, Zeng Z, Wei Y, Gao J, Zhang B, Li L, Liu L, Wan Y, Zeng Q, Gong Z, Liu L, Zhang H, Li Y, Yang S, Hu T, Wu L, Masliah E, Huang S, Cao H
Cellular & molecular immunology 2020 Mar;17(3):283-299
Cellular & molecular immunology 2020 Mar;17(3):283-299
Dose-dependent effects of tetramethylpyrazine on the characteristics of human umbilical cord mesenchymal stem cells for stroke therapy.
Cao H, Zhu X, Zhang J, Xu M, Ge L, Zhang C
Neuroscience letters 2020 Mar 23;722:134797
Neuroscience letters 2020 Mar 23;722:134797
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
Frew J, Baradaran-Heravi A, Balgi AD, Wu X, Yan TD, Arns S, Shidmoossavee FS, Tan J, Jaquith JB, Jansen-West KR, Lynn FC, Gao FB, Petrucelli L, Feldman HH, Mackenzie IR, Roberge M, Nygaard HB
Molecular neurodegeneration 2020 Mar 16;15(1):21
Molecular neurodegeneration 2020 Mar 16;15(1):21
Rapid and Efficient Invasion Assay of Glioblastoma in Human Brain Organoids.
Goranci-Buzhala G, Mariappan A, Gabriel E, Ramani A, Ricci-Vitiani L, Buccarelli M, D'Alessandris QG, Pallini R, Gopalakrishnan J
Cell reports 2020 Jun 9;31(10):107738
Cell reports 2020 Jun 9;31(10):107738
Single-Cell Analysis for Glycogen Localization and Metabolism in Cultured Astrocytes.
Zhu Y, Fan Z, Wang R, Xie R, Guo H, Zhang M, Guo B, Sun T, Zhang H, Zhuo L, Li Y, Wu S
Cellular and molecular neurobiology 2020 Jul;40(5):801-812
Cellular and molecular neurobiology 2020 Jul;40(5):801-812
Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates.
Gosset P, Maxan A, Alpaugh M, Breger L, Dehay B, Tao Z, Ling Z, Qin C, Cisbani G, Fortin N, Vonsattel JG, Lacroix S, Oueslati A, Bezard E, Cicchetti F
Neurobiology of disease 2020 Jul;141:104941
Neurobiology of disease 2020 Jul;141:104941
Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles.
Cone AS, Hurwitz SN, Lee GS, Yuan X, Zhou Y, Li Y, Meckes DG Jr
BMC molecular and cell biology 2020 Jul 30;21(1):58
BMC molecular and cell biology 2020 Jul 30;21(1):58
Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene.
Wang X, Xie S, Li Z, Ye Z, Gu X, Zhou L, Li H
Stem cell research 2020 Jan;42:101703
Stem cell research 2020 Jan;42:101703
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
Yang J, Cao H, Guo S, Zhu H, Tao H, Zhang L, Chen Z, Sun T, Chi S, Hu Q
Molecular medicine reports 2020 Dec;22(6):4763-4771
Molecular medicine reports 2020 Dec;22(6):4763-4771
MicroRNA Let-7b-5p Induces Electroacupuncture Tolerance by Downregulating the MKP-1 Gene in Rats Subjected to CFA-induced Inflammatory Nociception.
Zhang Q, Abouelfetouh MM, Chen S, Li M, Ding M, Ding Y
Journal of molecular neuroscience : MN 2020 Aug;70(8):1198-1207
Journal of molecular neuroscience : MN 2020 Aug;70(8):1198-1207
Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro.
Liu Q, Tan Y, Qu T, Zhang J, Duan X, Xu H, Mu Y, Ma H, Wang F
Life sciences 2020 Aug 1;254:117772
Life sciences 2020 Aug 1;254:117772
High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia.
Sun Y, Hei M, Fang Z, Tang Z, Wang B, Hu N
Frontiers in cellular neuroscience 2019;13:506
Frontiers in cellular neuroscience 2019;13:506
Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2.
Yang SC, Liu JJ, Wang CK, Lin YT, Tsai SY, Chen WJ, Huang WK, Tu PA, Lin YC, Chang CF, Cheng CL, Lin H, Lai CY, Lin CY, Lee YH, Chiu YC, Hsu CC, Hsu SC, Hsiao M, Schuyler SC, Lu FL, Lu J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10577-10592
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10577-10592
A dual-enzymatically cross-linked injectable gelatin hydrogel loaded with BMSC improves neurological function recovery of traumatic brain injury in rats.
Yao M, Gao F, Xu R, Zhang J, Chen Y, Guan F
Biomaterials science 2019 Sep 24;7(10):4088-4098
Biomaterials science 2019 Sep 24;7(10):4088-4098
Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats.
Li PJ, Guo YQ, Ding PY, Liu RB, Deng F, Feng XX, Yan WJ
Neurological research 2019 Oct;41(10):867-874
Neurological research 2019 Oct;41(10):867-874
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
He F, Dai R, Zhou X, Li X, Song X, Yan H, Meng Q, Yang C, Lin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Probucol, a "non-statin" cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice.
Huang JL, Yu C, Su M, Yang SM, Zhang F, Chen YY, Liu JY, Jiang YF, Zhong ZG, Wu DP
Aging 2019 Oct 7;11(19):8542-8555
Aging 2019 Oct 7;11(19):8542-8555
Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Yang HM, Li SZ
Brain sciences 2019 Oct 12;9(10)
Brain sciences 2019 Oct 12;9(10)
Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion.
He GQ, Xu WM, Liao HJ, Jiang C, Li CQ, Zhang W
Neural regeneration research 2019 Nov;14(11):1977-1985
Neural regeneration research 2019 Nov;14(11):1977-1985
Talin promotes integrin activation accompanied by generation of tension in talin and an increase in osmotic pressure in neurite outgrowth.
Wang Y, Zhang X, Tian J, Shan J, Hu Y, Zhai Y, Guo J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6311-6326
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6311-6326
Multi-site dynamic recording for Aβ oligomers-induced Alzheimer's disease in vitro based on neuronal network chip.
Gao F, Gao K, He C, Liu M, Wan H, Wang P
Biosensors & bioelectronics 2019 May 15;133:183-191
Biosensors & bioelectronics 2019 May 15;133:183-191
Treadmill exercise ameliorates focal cerebral ischemia/reperfusion-induced neurological deficit by promoting dendritic modification and synaptic plasticity via upregulating caveolin-1/VEGF signaling pathways.
Xie Q, Cheng J, Pan G, Wu S, Hu Q, Jiang H, Wang Y, Xiong J, Pang Q, Chen X
Experimental neurology 2019 Mar;313:60-78
Experimental neurology 2019 Mar;313:60-78
Inhibitory effects of glucagon-like peptide-1 receptor on epilepsy.
Wen Y, Wu K, Xie Y, Dan W, Zhan Y, Shi Q
Biochemical and biophysical research communications 2019 Mar 26;511(1):79-86
Biochemical and biophysical research communications 2019 Mar 26;511(1):79-86
Memantine can relieve the neuronal impairment caused by neurotropic virus infection.
Sun L, Zhou M, Liu C, Tang Y, Xiao K, Dai J, Gao Z, Siew L, Cao G, Wu X, Li L, Zhang R
Journal of medical virology 2019 Jun;91(6):935-940
Journal of medical virology 2019 Jun;91(6):935-940
Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Cells 2019 Jun 18;8(6)
Cells 2019 Jun 18;8(6)
Geniposide ameliorated fluoxetine-suppressed neurite outgrowth in Neuro2a neuroblastoma cells.
Chen MK, Peng CC, Maner RS, Zulkefli ND, Huang SM, Hsieh CL
Life sciences 2019 Jun 1;226:1-11
Life sciences 2019 Jun 1;226:1-11
Lentiviral-mediated ephrin B2 gene modification of rat bone marrow mesenchymal stem cells.
Zhu M, Hua Y, Tang J, Zhao X, Zhang L, Zhang Y
The Journal of international medical research 2019 Jul;47(7):3282-3298
The Journal of international medical research 2019 Jul;47(7):3282-3298
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
Wang K, Tian Y, Zhang Y, Li X, Wei X, Hu H, Xu S
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Zhong J, Lan C, Zhang C, Yang Y, Chen WX, Zhang KY, Zhao HL, Fang XY, Li HH, Tan L, Wang P, Ge HF, Hu R, Feng H
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, Hu J, Yang G, Jiang S
Life sciences 2019 Jul 15;229:187-199
Life sciences 2019 Jul 15;229:187-199
Zn(2+) Aggravates Tau Aggregation and Neurotoxicity.
Li X, Du X, Ni J
International journal of molecular sciences 2019 Jan 23;20(3)
International journal of molecular sciences 2019 Jan 23;20(3)
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
Zhao R, Ying M, Gu S, Yin W, Li Y, Yuan H, Fang S, Li M
Neuroscience 2019 Dec 1;422:99-118
Neuroscience 2019 Dec 1;422:99-118
JC virus infection of meningeal and choroid plexus cells in patients with progressive multifocal leukoencephalopathy.
Corbridge SM, Rice RC, Bean LA, Wüthrich C, Dang X, Nicholson DA, Koralnik IJ
Journal of neurovirology 2019 Aug;25(4):520-524
Journal of neurovirology 2019 Aug;25(4):520-524
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
Li HB
Heliyon 2019 Apr;5(4):e01567
Heliyon 2019 Apr;5(4):e01567
A single factor induces neuronal differentiation to suppress glioma cell growth.
Fu JQ, Chen Z, Hu YJ, Fan ZH, Guo ZX, Liang JY, Ryu BM, Ren JL, Shi XJ, Li J, Jia S, Wang J, Ke XS, Ma X, Tan X, Zhang T, Chen XZ, Zhang C
CNS neuroscience & therapeutics 2019 Apr;25(4):486-495
CNS neuroscience & therapeutics 2019 Apr;25(4):486-495
Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice.
Duan W, Guo M, Yi L, Zhang J, Bi Y, Liu Y, Li Y, Li Z, Ma Y, Zhang G, Liu Y, Song X, Li C
Aging 2019 Apr 30;11(8):2457-2476
Aging 2019 Apr 30;11(8):2457-2476
In Vitro Neural Differentiation of Bone Marrow Mesenchymal Stem Cells Carrying the FTH1 Reporter Gene and Detection with MRI.
Mu T, Qin Y, Liu B, He X, Liao Y, Sun J, Qiu J, Li X, Zhong Y, Cai J
BioMed research international 2018;2018:1978602
BioMed research international 2018;2018:1978602
Perineurial-like Cells and EMA Expression in the Suprachoroidal Region of the Human Eye.
Gilbert AR, Chévez-Barrios P, Cykowski MD
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2018 May;66(5):367-375
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2018 May;66(5):367-375
Pitavastatin treatment induces neuroprotection through the BDNF-TrkB signalling pathway in cultured cerebral neurons after oxygen-glucose deprivation.
Cui X, Fu Z, Wang M, Nan X, Zhang B
Neurological research 2018 May;40(5):391-397
Neurological research 2018 May;40(5):391-397
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J
Journal of neuroinflammation 2018 Jun 21;15(1):188
Journal of neuroinflammation 2018 Jun 21;15(1):188
Neuroserpin restores autophagy and promotes functional recovery after acute spinal cord injury in rats.
Li Z, Liu F, Zhang L, Cao Y, Shao Y, Wang X, Jiang X, Chen Z
Molecular medicine reports 2018 Feb;17(2):2957-2963
Molecular medicine reports 2018 Feb;17(2):2957-2963
Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence.
Ren HL, Lv CN, Xing Y, Geng Y, Zhang F, Bu W, Wang MW
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 23;24:1132-1144
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 23;24:1132-1144
Outcome of cell suspension allografts in a patient with Huntington's disease.
Maxan A, Mason S, Saint-Pierre M, Smith E, Ho A, Harrower T, Watts C, Tai Y, Pavese N, Savage JC, Tremblay MÈ, Gould P, Rosser AE, Dunnett SB, Piccini P, Barker RA, Cicchetti F
Annals of neurology 2018 Dec;84(6):950-956
Annals of neurology 2018 Dec;84(6):950-956
REST overexpression in mice causes deficits in spontaneous locomotion.
Lu L, Marisetty A, Liu B, Kamal MM, Gumin J, Veo B, Cai Y, Kassem DH, Weng C, Maynard ME, Hood KN, Fuller GN, Pan ZZ, Cykowski MD, Dash PK, Majumder S
Scientific reports 2018 Aug 14;8(1):12083
Scientific reports 2018 Aug 14;8(1):12083
Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing.
Park JJ, Weldon BA, Hong S, Workman T, Griffith WC, Park JH, Faustman EM
Toxicology in vitro : an international journal published in association with BIBRA 2018 Apr;48:33-44
Toxicology in vitro : an international journal published in association with BIBRA 2018 Apr;48:33-44
Improved Neural Regeneration with Olfactory Ensheathing Cell Inoculated PLGA Scaffolds in Spinal Cord Injury Adult Rats.
Wang C, Sun C, Hu Z, Huo X, Yang Y, Liu X, Botchway BOA, Davies H, Fang M
Neuro-Signals 2017;25(1):1-14
Neuro-Signals 2017;25(1):1-14
An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.
Liu J, Wang L, Du Y, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2017 Oct;4(10):1700089
The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission.
Chen L, Ning H, Yin Z, Song X, Feng Y, Qin H, Li Y, Wang J, Ge Y, Wang W
Chemosphere 2017 Oct;185:589-594
Chemosphere 2017 Oct;185:589-594
miR-200c regulates endothelin-1 induced PASMCs abnormal proliferation and apoptosis.
Yuan C, Xu M, Rong R, Mei Y, Cai W, Li L, Xue Y, Zhu B, Sun K, Han L
IUBMB life 2017 Nov;69(11):877-886
IUBMB life 2017 Nov;69(11):877-886
Involvement of intracellular transport in TREK-1c current run-up in 293T cells.
Andharia N, Joseph A, Hayashi M, Okada M, Matsuda H
Channels (Austin, Tex.) 2017 May 4;11(3):224-235
Channels (Austin, Tex.) 2017 May 4;11(3):224-235
Anterograde monosynaptic transneuronal tracers derived from herpes simplex virus 1 strain H129.
Zeng WB, Jiang HF, Gang YD, Song YG, Shen ZZ, Yang H, Dong X, Tian YL, Ni RJ, Liu Y, Tang N, Li X, Jiang X, Gao D, Androulakis M, He XB, Xia HM, Ming YZ, Lu Y, Zhou JN, Zhang C, Xia XS, Shu Y, Zeng SQ, Xu F, Zhao F, Luo MH
Molecular neurodegeneration 2017 May 12;12(1):38
Molecular neurodegeneration 2017 May 12;12(1):38
Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids.
Gabriel E, Ramani A, Karow U, Gottardo M, Natarajan K, Gooi LM, Goranci-Buzhala G, Krut O, Peters F, Nikolic M, Kuivanen S, Korhonen E, Smura T, Vapalahti O, Papantonis A, Schmidt-Chanasit J, Riparbelli M, Callaini G, Krönke M, Utermöhlen O, Gopalakrishnan J
Cell stem cell 2017 Mar 2;20(3):397-406.e5
Cell stem cell 2017 Mar 2;20(3):397-406.e5
Neuropeptide Y suppresses epileptiform discharges by regulating AMPA receptor GluR2 subunit in rat hippocampal neurons.
Bu W, Zhao WQ, Li WL, Dong CZ, Zhang Z, Li QJ
Molecular medicine reports 2017 Jul;16(1):387-395
Molecular medicine reports 2017 Jul;16(1):387-395
RNA stores tau reversibly in complex coacervates.
Zhang X, Lin Y, Eschmann NA, Zhou H, Rauch JN, Hernandez I, Guzman E, Kosik KS, Han S
PLoS biology 2017 Jul;15(7):e2002183
PLoS biology 2017 Jul;15(7):e2002183
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Gao Y, Mruk D, Chen H, Lui WY, Lee WM, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
Mutant huntingtin protein expression and blood-spinal cord barrier dysfunction in huntington disease.
Sciacca G, Cicchetti F
Annals of neurology 2017 Dec;82(6):981-994
Annals of neurology 2017 Dec;82(6):981-994
Transplantation of VEGF-mediated bone marrow mesenchymal stem cells promotes functional improvement in a rat acute cerebral infarction model.
Zong X, Wu S, Li F, Lv L, Han D, Zhao N, Yan X, Hu S, Xu T
Brain research 2017 Dec 1;1676:9-18
Brain research 2017 Dec 1;1676:9-18
rhEPO Enhances Cellular Anti-oxidant Capacity to Protect Long-Term Cultured Aging Primary Nerve Cells.
Wang H, Fan J, Chen M, Yao Q, Gao Z, Zhang G, Wu H, Yu X
Journal of molecular neuroscience : MN 2017 Aug;62(3-4):291-303
Journal of molecular neuroscience : MN 2017 Aug;62(3-4):291-303
Claulansine F promoted the neuronal differentiation of neural stem and progenitor cells through Akt/GSK-3β/β-catenin pathway.
Huang JY, Ma YZ, Yuan YH, Zuo W, Chu SF, Liu H, Du GH, Zhang DM, Chen NH
European journal of pharmacology 2016 Sep 5;786:72-84
European journal of pharmacology 2016 Sep 5;786:72-84
Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells.
Kim HY, Wegner SH, Van Ness KP, Park JJ, Pacheco SE, Workman T, Hong S, Griffith W, Faustman EM
Reproductive toxicology (Elmsford, N.Y.) 2016 Oct;65:212-223
Reproductive toxicology (Elmsford, N.Y.) 2016 Oct;65:212-223
Human-to-mouse prion-like propagation of mutant huntingtin protein.
Jeon I, Cicchetti F, Cisbani G, Lee S, Li E, Bae J, Lee N, Li L, Im W, Kim M, Kim HS, Oh SH, Kim TA, Ko JJ, Aubé B, Oueslati A, Kim YJ, Song J
Acta neuropathologica 2016 Oct;132(4):577-92
Acta neuropathologica 2016 Oct;132(4):577-92
Evaluation of histopathological changes in the microstructure at the center and periphery of glioma tumors using diffusional kurtosis imaging.
Li F, Shi W, Wang D, Xu Y, Li H, He J, Zeng Q
Clinical neurology and neurosurgery 2016 Dec;151:120-127
Clinical neurology and neurosurgery 2016 Dec;151:120-127
Endoplasmic reticulum stress mediates JNK-dependent IRS-1 serine phosphorylation and results in Tau hyperphosphorylation in amyloid β oligomer-treated PC12 cells and primary neurons.
Zhang X, Tang S, Zhang Q, Shao W, Han X, Wang Y, Du Y
Gene 2016 Aug 10;587(2):183-93
Gene 2016 Aug 10;587(2):183-93
Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury.
He G, Xu W, Tong L, Li S, Su S, Tan X, Li C
Apoptosis : an international journal on programmed cell death 2016 Apr;21(4):390-403
Apoptosis : an international journal on programmed cell death 2016 Apr;21(4):390-403
Headless Myo10 is a regulator of microtubule stability during neuronal development.
Yu H, Sun D, Wang N, Wang M, Lan Y, Fan W, Zhao Y, Guo W, Zhu X
Journal of neurochemistry 2015 Oct;135(2):261-73
Journal of neurochemistry 2015 Oct;135(2):261-73
Viral Infection of the Central Nervous System and Neuroinflammation Precede Blood-Brain Barrier Disruption during Japanese Encephalitis Virus Infection.
Li F, Wang Y, Yu L, Cao S, Wang K, Yuan J, Wang C, Wang K, Cui M, Fu ZF
Journal of virology 2015 May;89(10):5602-14
Journal of virology 2015 May;89(10):5602-14
Increased stathmin expression strengthens fear conditioning in epileptic rats.
Zhang L, Feng D, Tao H, DE X, Chang Q, Hu Q
Biomedical reports 2015 Jan;3(1):28-32
Biomedical reports 2015 Jan;3(1):28-32
Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells.
He GQ, Xu WM, Li JF, Li SS, Liu B, Tan XD, Li CQ
Molecular brain 2015 Dec 23;8:88
Molecular brain 2015 Dec 23;8:88
The effects of harvesting media on biological characteristics and repair potential of neural stem cells after traumatic brain injury.
Liu S, Li Z, Fu J, Sun L, Xu F, Harada T, Lou Y, Chu M, Sun Q, Xu K, Zhang R, Jin L, Xiao H, Wu S
PloS one 2014;9(9):e107865
PloS one 2014;9(9):e107865
AxonQuant: A Microfluidic Chamber Culture-Coupled Algorithm That Allows High-Throughput Quantification of Axonal Damage.
Li Y, Yang M, Huang Z, Chen X, Maloney MT, Zhu L, Liu J, Yang Y, Du S, Jiang X, Wu JY
Neuro-Signals 2014;22(1):14-29
Neuro-Signals 2014;22(1):14-29
Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.
Yin F, Meng C, Lu R, Li L, Zhang Y, Chen H, Qin Y, Guo L
Neural regeneration research 2014 Sep 15;9(18):1665-71
Neural regeneration research 2014 Sep 15;9(18):1665-71
Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury.
Yin F, Guo L, Meng CY, Liu YJ, Lu RF, Li P, Zhou YB
Brain research 2014 May 2;1561:1-10
Brain research 2014 May 2;1561:1-10
Neuropeptide Y protects cerebral cortical neurons by regulating microglial immune function.
Li Q, Dong C, Li W, Bu W, Wu J, Zhao W
Neural regeneration research 2014 May 1;9(9):959-67
Neural regeneration research 2014 May 1;9(9):959-67
Mutant huntingtin is present in neuronal grafts in Huntington disease patients.
Cicchetti F, Lacroix S, Cisbani G, Vallières N, Saint-Pierre M, St-Amour I, Tolouei R, Skepper JN, Hauser RA, Mantovani D, Barker RA, Freeman TB
Annals of neurology 2014 Jul;76(1):31-42
Annals of neurology 2014 Jul;76(1):31-42
Effects of targeted suppression of glutaryl-CoA dehydrogenase by lentivirus-mediated shRNA and excessive intake of lysine on apoptosis in rat striatal neurons.
Gao J, Zhang C, Fu X, Yi Q, Tian F, Ning Q, Luo X
PloS one 2013;8(5):e63084
PloS one 2013;8(5):e63084
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 17490-1-AP(MAP2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using 17490-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MAP2 (IP:17490-1-AP, 3ug; Detection:17490-1-AP 1:1000) with mouse brain tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17490-1-AP(MAP2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17490-1-AP(MAP2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
