Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 55125-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55125-1-AP, RRID:AB_10858795
- Product name
- PTPRZ1 antibody
- Antibody type
- Polyclonal
- Description
- PTPRZ1 antibody (Cat. #55125-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Integrative spatial multi-omics identifies the TEK receptor tyrosine kinase as a central biomacromolecule of endothelial-immune interactions in glioblastoma.
Echinacoside targets the HIF-1α/LDHA axis to modulate A1/A2 astrocyte differentiation and promote glial scar repair following ischemic stroke.
Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma.
Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice.
Targeting the PTN/PTPRZ1-ROS Pathway to Promote Bone Regeneration.
Single-nucleus RNA sequencing-based construction of a hippocampal neuron atlas in mice with epileptic cognitive impairment.
IL-34 and its receptors as predictors of brain metastasis and prognosis in lung adenocarcinoma: Unveiling insights through bioinformatic and immunohistochemical investigations.
PTPRZ1 dephosphorylates and stabilizes RNF26 to reduce the efficacy of TKIs and PD-1 blockade in ccRCC.
Data-independent acquisition combined with liquid chromatography mass spectrometry technique to detect prognostic protein markers in type I gastric neuroendocrine neoplasm.
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Yu Z, Zhou Q, Wang XA, Liu H, Shang R, Shen Y, Zhang J, Gao A, Liang H
International journal of biological macromolecules 2025 Sep;322(Pt 3):146964
International journal of biological macromolecules 2025 Sep;322(Pt 3):146964
Echinacoside targets the HIF-1α/LDHA axis to modulate A1/A2 astrocyte differentiation and promote glial scar repair following ischemic stroke.
Liao Y, Yang L, Guo C, Hu J, Wen L, Ju B, Hou Q, Zhu H, Ding Y, Yang J, Zhao M
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120375
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120375
Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma.
Ning YQ, Wang J, Zhang Y, Li H, Jiang Z, Su X, Yang X, Wu X, Wei B, Ying J, Yan J, Li W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09344
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09344
Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice.
Chi D, Zhang K, Zhang J, He Z, Zhou H, Huang W, Liu Y, Huang J, Zeng W, Bai X, Ou C, Ouyang H
Nature communications 2025 Mar 14;16(1):2528
Nature communications 2025 Mar 14;16(1):2528
Targeting the PTN/PTPRZ1-ROS Pathway to Promote Bone Regeneration.
Zhao K, Guo Y, He Y, Wu Y, Hu Z, Chi X, Deng X
Biomedicines 2025 Mar 12;13(3)
Biomedicines 2025 Mar 12;13(3)
Single-nucleus RNA sequencing-based construction of a hippocampal neuron atlas in mice with epileptic cognitive impairment.
Ma JQ, Wang L, Zhang Y, Bian YQ, Qu XP, Song LJ, Wang C, Gao L, Fang QX, Zhao DC, Shen LL, Liu B
iScience 2024 Oct 18;27(10):111065
iScience 2024 Oct 18;27(10):111065
IL-34 and its receptors as predictors of brain metastasis and prognosis in lung adenocarcinoma: Unveiling insights through bioinformatic and immunohistochemical investigations.
Geng J, Xu S, Cao Y, Liu F, Ren X, Che D, Pan B, Yu Y
Heliyon 2024 Jul 15;10(13):e33791
Heliyon 2024 Jul 15;10(13):e33791
PTPRZ1 dephosphorylates and stabilizes RNF26 to reduce the efficacy of TKIs and PD-1 blockade in ccRCC.
Ma Y, Li W, Liu X, Peng W, Qing B, Ren S, Liu W, Chen X
Oncogene 2024 Dec;43(50):3633-3644
Oncogene 2024 Dec;43(50):3633-3644
Data-independent acquisition combined with liquid chromatography mass spectrometry technique to detect prognostic protein markers in type I gastric neuroendocrine neoplasm.
Zhang M, Zheng X, Wang C, Li S
Rapid communications in mass spectrometry : RCM 2024 Aug 30;38(16):e9849
Rapid communications in mass spectrometry : RCM 2024 Aug 30;38(16):e9849
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Ma L, Shen T, Peng H, Wu J, Wang W, Gao X
Journal of oncology 2022;2022:2352360
Journal of oncology 2022;2022:2352360
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Liu Z, Yan M, Lei W, Jiang R, Dai W, Chen J, Wang C, Li L, Wu M, Nian X, Li D, Sun D, Lv X, Wang C, Xie C, Yao L, Wu C, Hu J, Xiao N, Mo W, Wang Z, Zhang L
The Journal of clinical investigation 2022 Apr 1;132(7)
The Journal of clinical investigation 2022 Apr 1;132(7)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PTPRZ1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human PTPRZ1. This antibody recognizes human, mouse, rat antigen. The PTPRZ1 antibody has been validated for the following applications: ELISA, WB analysis.