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- Antibody Data
- Antigen structure
- References [17]
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- Immunohistochemistry [1]
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- Product number
- HPA015103 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA015103, RRID:AB_1855946
- Product name
- Anti-PTPRZ1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PTPRZ1, Gene description: protein tyrosine phosphatase, receptor-type, Z polypeptide 1, Alternative Gene Names: phosphacan, PTP18, PTPRZ, PTPZ, RPTPB, Validated applications: IHC, WB, Uniprot ID: P23471, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Integrin α6β4 Upregulates PTPRZ1 Through UCHL1-Mediated Hif-1α Nuclear Accumulation to Promote Triple-Negative Breast Cancer Cell Invasive Properties
HSV1 microRNAs in glioblastoma development: an in silico study
A cell fate decision map reveals abundant direct neurogenesis bypassing intermediate progenitors in the human developing neocortex.
Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth
FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells
Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity
Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids.
Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells.
Centrosome anchoring regulates progenitor properties and cortical formation
Cell stress in cortical organoids impairs molecular subtype specification
Soluble protein tyrosine phosphatase receptor type Z (PTPRZ) in cerebrospinal fluid is a potential diagnostic marker for glioma
Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.
Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein
Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development
Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia
Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex
Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease.
Chen M, Karimpour P, Elliott A, He D, Knifley T, Liu J, Wang C, O’Connor K
Cancers 2024;16(21):3683
Cancers 2024;16(21):3683
HSV1 microRNAs in glioblastoma development: an in silico study
Abdoli Shadbad M, Hemmat N, Abdoli Shadbad M, Brunetti O, Silvestris N, Baradaran B
Scientific Reports 2024;14(1)
Scientific Reports 2024;14(1)
A cell fate decision map reveals abundant direct neurogenesis bypassing intermediate progenitors in the human developing neocortex.
Coquand L, Brunet Avalos C, Macé AS, Farcy S, Di Cicco A, Lampic M, Wimmer R, Bessières B, Attie-Bitach T, Fraisier V, Sens P, Guimiot F, Brault JB, Baffet AD
Nature cell biology 2024 May;26(5):698-709
Nature cell biology 2024 May;26(5):698-709
Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth
Nagai K, Muto Y, Miura S, Takahashi K, Naruse Y, Hiruta R, Hashimoto Y, Uzuki M, Haga Y, Fujii R, Ueda K, Kawaguchi Y, Fujii M, Kitazume S
Journal of Biological Chemistry 2023;299(9):105128
Journal of Biological Chemistry 2023;299(9):105128
FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells
Lancaster M, Park S, Kulkarni A, Konopka G
PLOS Biology 2023;21(8):e3001852
PLOS Biology 2023;21(8):e3001852
Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity
Lam K, Leon A, Hui W, Lee S, Batruch I, Faust K, Klekner A, Hutóczki G, Koritzinsky M, Richer M, Djuric U, Diamandis P
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids.
Fischer J, Fernández Ortuño E, Marsoner F, Artioli A, Peters J, Namba T, Eugster Oegema C, Huttner WB, Ladewig J, Heide M
EMBO reports 2022 Nov 7;23(11):e54728
EMBO reports 2022 Nov 7;23(11):e54728
Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells.
Rosebrock D, Arora S, Mutukula N, Volkman R, Gralinska E, Balaskas A, Aragonés Hernández A, Buschow R, Brändl B, Müller FJ, Arndt PF, Vingron M, Elkabetz Y
Nature cell biology 2022 Jun;24(6):981-995
Nature cell biology 2022 Jun;24(6):981-995
Centrosome anchoring regulates progenitor properties and cortical formation
Shao W, Yang J, He M, Yu X, Lee C, Yang Z, Joyner A, Anderson K, Zhang J, Tsou M, Shi H, Shi S
Nature 2020;580(7801):106-112
Nature 2020;580(7801):106-112
Cell stress in cortical organoids impairs molecular subtype specification
Bhaduri A, Andrews M, Mancia Leon W, Jung D, Shin D, Allen D, Jung D, Schmunk G, Haeussler M, Salma J, Pollen A, Nowakowski T, Kriegstein A
Nature 2020;578(7793):142-148
Nature 2020;578(7793):142-148
Soluble protein tyrosine phosphatase receptor type Z (PTPRZ) in cerebrospinal fluid is a potential diagnostic marker for glioma
Kitazume S, Saito K, Honda T, Hashimoto Y, Hoshi K, Nagai K, Murakami Y, Fujii M, Yamanoi Y
Neuro-Oncology Advances 2020;2(1)
Neuro-Oncology Advances 2020;2(1)
Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.
Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, Cadwell CR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, Mostajo-Radji MA, Huang EJ, Nowakowski TJ, Lim DA, Diaz A, Raleigh DR, Kriegstein AR
Cell stem cell 2020 Jan 2;26(1):48-63.e6
Cell stem cell 2020 Jan 2;26(1):48-63.e6
Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein
Bang-Christensen S, Pedersen R, Pereira M, Clausen T, Løppke C, Sand N, Ahrens T, Jørgensen A, Lim Y, Goksøyr L, Choudhary S, Gustavsson T, Dagil R, Daugaard M, Sander A, Torp M, Søgaard M, Theander T, Østrup O, Lassen U, Hamerlik P, Salanti A, Agerbæk M
Cells 2019;8(9):998
Cells 2019;8(9):998
Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development
Nakagawa N, Plestant C, Yabuno-Nakagawa K, Li J, Lee J, Huang C, Lee A, Krupa O, Adhikari A, Thompson S, Rhynes T, Arevalo V, Stein J, Molnár Z, Badache A, Anton E
Neuron 2019;103(5):836-852.e5
Neuron 2019;103(5):836-852.e5
Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia
Bershteyn M, Nowakowski T, Pollen A, Di Lullo E, Nene A, Wynshaw-Boris A, Kriegstein A
Cell Stem Cell 2017;20(4):435-449.e4
Cell Stem Cell 2017;20(4):435-449.e4
Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex
Wang L, Hou S, Han Y
Nature Neuroscience 2016;19(7):888-896
Nature Neuroscience 2016;19(7):888-896
Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease.
Khoonsari PE, Häggmark A, Lönnberg M, Mikus M, Kilander L, Lannfelt L, Bergquist J, Ingelsson M, Nilsson P, Kultima K, Shevchenko G
PloS one 2016;11(3):e0150672
PloS one 2016;11(3):e0150672
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and liver tissues using HPA015103 antibody. Corresponding PTPRZ1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
