ABIN234532

antibody from antibodies-online

Targeting: KIR2DL2

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN234532

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN234532, RRID:AB_10773095

Product name

anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) antibody

Antibody type

Monoclonal

Antigen

NK cell clone E57 (CD2+, CD3-, CD7+, CD16+, CD56+)

Description

Protein A Chromatography. Ascites

Reactivity

Human

Host

Mouse

Antibody clone number

GL183

Vial size

0.2 mg

Concentration

0.2 mg/mL (prior to lyophilization)

Storage

Store lyophilized product at 2-8°C. After reconstitution, aliquot and store at -20°C.

Handling

Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage of the Reconstituted liquid for up to one month at 2-8°C.

References

Submitted references

Natural killer cell receptors and MHC class I interactions.

Lanier LL
Current opinion in immunology 1997 Feb;9(1):126-31

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Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations.

Mingari MC, Schiavetti F, Ponte M, Vitale C, Maggi E, Romagnani S, Demarest J, Pantaleo G, Fauci AS, Moretta L
Proceedings of the National Academy of Sciences of the United States of America 1996 Oct 29;93(22):12433-8

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The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

Biassoni R, Cantoni C, Falco M, Verdiani S, Bottino C, Vitale M, Conte R, Poggi A, Moretta A, Moretta L
The Journal of experimental medicine 1996 Feb 1;183(2):645-50

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Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

Moretta A, Sivori S, Vitale M, Pende D, Morelli L, Augugliaro R, Bottino C, Moretta L
The Journal of experimental medicine 1995 Sep 1;182(3):875-84

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Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

Wagtmann N, Biassoni R, Cantoni C, Verdiani S, Malnati MS, Vitale M, Bottino C, Moretta L, Moretta A, Long EO
Immunity 1995 May;2(5):439-49

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T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function.

Ferrini S, Cambiaggi A, Meazza R, Sforzini S, Marciano S, Mingari MC, Moretta L
European journal of immunology 1994 Oct;24(10):2294-8

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A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

Moretta A, Tambussi G, Bottino C, Tripodi G, Merli A, Ciccone E, Pantaleo G, Moretta L
The Journal of experimental medicine 1990 Mar 1;171(3):695-714

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Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

Moretta A, Bottino C, Pende D, Tripodi G, Tambussi G, Viale O, Orengo A, Barbaresi M, Merli A, Ciccone E
The Journal of experimental medicine 1990 Dec 1;172(6):1589-98