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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA011916 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA011916, RRID:AB_1857692
- Product name
- Anti-SYNJ1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SYNJ1, Gene description: synaptojanin 1, Alternative Gene Names: INPP5G, Validated applications: IHC, ICC, Uniprot ID: O43426, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism.
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons
The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer’s disease
Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability
Ng X, Wu Y, Lin Y, Yaqoob S, Greene L, De Camilli P, Cao M
npj Parkinson's Disease 2023;9(1)
npj Parkinson's Disease 2023;9(1)
Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism.
Choong CJ, Aguirre C, Kakuda K, Beck G, Nakanishi H, Kimura Y, Shimma S, Nabekura K, Hideshima M, Doi J, Yamaguchi K, Nakajima K, Wadayama T, Hayakawa H, Baba K, Ogawa K, Takeuchi T, Badawy SMM, Murayama S, Nagano S, Goto Y, Miyanoiri Y, Nagai Y, Mochizuki H, Ikenaka K
Acta neuropathologica 2023 May;145(5):573-595
Acta neuropathologica 2023 May;145(5):573-595
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons
Wu C, Vinton E, Pearse R, Heo K, Aylward A, Hsieh Y, Bi Y, Adeleye S, Fancher S, Duong D, Seyfried N, Schwarz T, Young-Pearse T
Molecular Psychiatry 2022;27(4):1970-1989
Molecular Psychiatry 2022;27(4):1970-1989
The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer’s disease
Ando K, Ndjim M, Turbant S, Fontaine G, Pregoni G, Dauphinot L, Yilmaz Z, Suain V, Mansour S, Authelet M, De Dekker R, Leroy K, Delatour B, Letournel F, Martin-Négrier M, Chapon F, Godfraind C, Maurage C, Deramecourt V, Meyronnet D, Streichenberger N, de Paula A, Rigau V, Vandenbos-Burel F, Duyckaerts C, Seilhean D, Boluda S, Plu I, Milin S, Chiforeanu D, Laquerrière A, Lannes B, Duyckaerts C, Potier M, Brion J
Acta Neuropathologica Communications 2020;8(1)
Acta Neuropathologica Communications 2020;8(1)
Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability
Vivas O, Tiscione S, Dixon R, Ory D, Dickson E
Cell Reports 2019;27(9):2636-2648.e4
Cell Reports 2019;27(9):2636-2648.e4
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and skeletal muscle tissues using HPA011916 antibody. Corresponding SYNJ1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
