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Learn18274-1-AP
antibody from Proteintech Group
Targeting: ATP6V0D1
ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 18274-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18274-1-AP, RRID:AB_2258877
- Product name
- ATP6V0D1 antibody
- Antibody type
- Polyclonal
- Description
- ATP6V0D1 antibody (Cat. #18274-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Time of exercise differentially impacts bone growth in mice.
Alkaliptosis induction counteracts paclitaxel-resistant ovarian cancer cells via ATP6V0D1-mediated ABCB1 inhibition.
Spatiotemporal roles of AMPK in PARP-1- and autophagy-dependent retinal pigment epithelial cell death caused by UVA.
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Identification of Novel Senescent Markers in Small Extracellular Vesicles.
A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c.
Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly.
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.
Upregulation of V-ATPase by STAT3 Activation Promotes Anoikis Resistance and Tumor Metastasis.
The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.
DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function.
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.
Disruption of the vacuolar-type H(+)-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes.
Quantitative proteomics reveals olfactory input-dependent alterations in the mouse olfactory bulb proteome.
Lysosomal storage causes cellular dysfunction in mucolipidosis II skin fibroblasts.
Yu S, Tang Q, Lu X, Chen G, Xie M, Yang J, Yin Y, Zheng W, Wang J, Han Y, Zhang L, Chen L
Nature metabolism 2024 Jun;6(6):1036-1052
Nature metabolism 2024 Jun;6(6):1036-1052
Alkaliptosis induction counteracts paclitaxel-resistant ovarian cancer cells via ATP6V0D1-mediated ABCB1 inhibition.
Chen F, Lin J, Kang R, Tang D, Liu J
Molecular carcinogenesis 2024 Aug;63(8):1515-1527
Molecular carcinogenesis 2024 Aug;63(8):1515-1527
Spatiotemporal roles of AMPK in PARP-1- and autophagy-dependent retinal pigment epithelial cell death caused by UVA.
Wu AY, Sekar P, Huang DY, Hsu SH, Chan CM, Lin WW
Journal of biomedical science 2023 Nov 7;30(1):91
Journal of biomedical science 2023 Nov 7;30(1):91
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Chen F, Zhu S, Kang R, Tang D, Liu J
Cell reports 2023 Jan 31;42(1):111911
Cell reports 2023 Jan 31;42(1):111911
Identification of Novel Senescent Markers in Small Extracellular Vesicles.
Misawa T, Hitomi K, Miyata K, Tanaka Y, Fujii R, Chiba M, Loo TM, Hanyu A, Kawasaki H, Kato H, Maezawa Y, Yokote K, Nakamura AJ, Ueda K, Yaegashi N, Takahashi A
International journal of molecular sciences 2023 Jan 26;24(3)
International journal of molecular sciences 2023 Jan 26;24(3)
A Role for the V0 Sector of the V-ATPase in Neuroexocytosis: Exogenous V0d Blocks Complexin and SNARE Interactions with V0c.
Lévêque C, Maulet Y, Wang Q, Rame M, Rodriguez L, Mochida S, Sangiardi M, Youssouf F, Iborra C, Seagar M, Vitale N, El Far O
Cells 2023 Feb 26;12(5)
Cells 2023 Feb 26;12(5)
Zinc enhances autophagic flux and lysosomal function through transcription factor EB activation and V-ATPase assembly.
Kim KR, Park SE, Hong JY, Koh JY, Cho DH, Hwang JJ, Kim YH
Frontiers in cellular neuroscience 2022;16:895750
Frontiers in cellular neuroscience 2022;16:895750
Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.
Wang F, Yang Y, Boudagh G, Eskelinen EL, Klionsky DJ, Malek SN
Autophagy 2022 Aug;18(8):1982-2000
Autophagy 2022 Aug;18(8):1982-2000
Upregulation of V-ATPase by STAT3 Activation Promotes Anoikis Resistance and Tumor Metastasis.
Adeshakin FO, Adeshakin AO, Liu Z, Lu X, Cheng J, Zhang P, Yan D, Zhang G, Wan X
Journal of Cancer 2021;12(16):4819-4829
Journal of Cancer 2021;12(16):4819-4829
The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.
Castroflorio E, den Hoed J, Svistunova D, Finelli MJ, Cebrian-Serrano A, Corrochano S, Bassett AR, Davies B, Oliver PL
Cellular and molecular life sciences : CMLS 2021 Apr;78(7):3503-3524
Cellular and molecular life sciences : CMLS 2021 Apr;78(7):3503-3524
DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function.
Cao Y, Li R, Shen M, Li C, Zou Y, Jiang Q, Liu S, Lu C, Li H, Liu H, Cai Y
Cell death & disease 2021 Apr 20;12(5):416
Cell death & disease 2021 Apr 20;12(5):416
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Zhong B, Liu M, Bai C, Ruan Y, Wang Y, Qiu L, Hong Y, Wang X, Li L, Li B
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.
Rao VK, Zavala G, Deb Roy A, Mains RE, Eipper BA
Journal of cellular physiology 2019 Jun;234(6):8683-8697
Journal of cellular physiology 2019 Jun;234(6):8683-8697
Disruption of the vacuolar-type H(+)-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes.
Kissing S, Rudnik S, Damme M, Lüllmann-Rauch R, Ichihara A, Kornak U, Eskelinen EL, Jabs S, Heeren J, De Brabander JK, Haas A, Saftig P
Autophagy 2017 Apr 3;13(4):670-685
Autophagy 2017 Apr 3;13(4):670-685
Quantitative proteomics reveals olfactory input-dependent alterations in the mouse olfactory bulb proteome.
Zeng HL, Rao X, Zhang LK, Zhao X, Zhang WP, Wang J, Xu F, Guo L
Journal of proteomics 2014 Sep 23;109:125-42
Journal of proteomics 2014 Sep 23;109:125-42
Lysosomal storage causes cellular dysfunction in mucolipidosis II skin fibroblasts.
Otomo T, Higaki K, Nanba E, Ozono K, Sakai N
The Journal of biological chemistry 2011 Oct 7;286(40):35283-90
The Journal of biological chemistry 2011 Oct 7;286(40):35283-90
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 18274-1-AP(ATP6V0D1 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 18274-1-AP(ATP6V0D1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 18274-1-AP(ATP6V0D1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATP6V0D1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATP6V0D1. This antibody recognizes human,mouse,rat antigen. The ATP6V0D1 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
