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- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA023483 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA023483, RRID:AB_1857625
- Product name
- Anti-STXBP1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human STXBP1, Gene description: syntaxin binding protein 1, Alternative Gene Names: hUNC18, MUNC18-1, rbSec1, UNC18, Validated applications: WB, IHC, Uniprot ID: P61764, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Reduced synaptic depression in human neurons carrying homozygous disease-causing STXBP1 variant L446F
Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability
Öttl M, Toonen R, Verhage M
Human Molecular Genetics 2024;33(11):991-1000
Human Molecular Genetics 2024;33(11):991-1000
Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability
dos Santos A, Larsen S, Guo L, Barbagallo P, Montalant A, Verhage M, Sørensen J, Perrier J
Cell Reports Medicine 2023;4(12):101308
Cell Reports Medicine 2023;4(12):101308
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and liver tissues using HPA023483 antibody. Corresponding STXBP1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
