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- Antigen structure
- References [13]
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- Western blot [1]
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- Product number
- 11459-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11459-1-AP, RRID:AB_2196690
- Product name
- STXBP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STXBP1 antibody (Cat. #11459-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Clinical and functional characterization of a novel KCNJ11 (c.101G > A, p.R34H) mutation associated with maturity-onset diabetes mellitus of the young type 13.
Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release.
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Construction of the metabolism-related models for predicting prognosis and infiltrating immune phenotype in lung squamous cell carcinoma.
Identification of residues critical for the extension of Munc18-1 domain 3a.
Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.
Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance.
SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assembly.
Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly.
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Lv X, Gao J, Yang J, Zou Y, Chen J, Sun Y, Song J, Liu Y, Wang L, Xia L, Yu S, Wei Z, Chen L, Hou X
Endocrine 2024 Nov;86(2):515-527
Endocrine 2024 Nov;86(2):515-527
Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release.
Zhang H, Lei M, Zhang Y, Li H, He Z, Xie S, Zhu L, Wang S, Liu J, Li Y, Lu Y, Ma C
Science advances 2024 May 17;10(20):eadi7024
Science advances 2024 May 17;10(20):eadi7024
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Wang L, Chen J, Song J, Xiang Y, Yang M, Xia L, Yang J, Hou X, Chen L, Wang L
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Construction of the metabolism-related models for predicting prognosis and infiltrating immune phenotype in lung squamous cell carcinoma.
Ma Z, Wang L, Huang X, Ji H, Wang H, Yang Y, Ma Y, Chen J
Journal of Cancer 2023;14(18):3539-3549
Journal of Cancer 2023;14(18):3539-3549
Identification of residues critical for the extension of Munc18-1 domain 3a.
Wang X, Gong J, Zhu L, Chen H, Jin Z, Mo X, Wang S, Yang X, Ma C
BMC biology 2023 Jul 13;21(1):158
BMC biology 2023 Jul 13;21(1):158
Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.
Murtaza N, Cheng AA, Brown CO, Meka DP, Hong S, Uy JA, El-Hajjar J, Pipko N, Unda BK, Schwanke B, Xing S, Thiruvahindrapuram B, Engchuan W, Trost B, Deneault E, Calderon de Anda F, Doble BW, Ellis J, Anagnostou E, Bader GD, Scherer SW, Lu Y, Singh KK
Cell reports 2022 Nov 22;41(8):111678
Cell reports 2022 Nov 22;41(8):111678
Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance.
Datta P, Cribbs JT, Seo S
PloS one 2021;16(5):e0246358
PloS one 2021;16(5):e0246358
SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Duan XL, Guo Z, He YT, Li YX, Liu YN, Bai HH, Li HL, Hu XD, Suo ZW
Neuroscience 2020 Mar 1;429:203-212
Neuroscience 2020 Mar 1;429:203-212
Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assembly.
Wang X, Gong J, Zhu L, Wang S, Yang X, Xu Y, Yang X, Ma C
The EMBO journal 2020 Aug 17;39(16):e103631
The EMBO journal 2020 Aug 17;39(16):e103631
Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Zhou H, Wei Z, Wang S, Yao D, Zhang R, Ma C
Cell reports 2019 Mar 19;26(12):3347-3359.e6
Cell reports 2019 Mar 19;26(12):3347-3359.e6
Munc18 and Munc13 serve as a functional template to orchestrate neuronal SNARE complex assembly.
Wang S, Li Y, Gong J, Ye S, Yang X, Zhang R, Ma C
Nature communications 2019 Jan 8;10(1):69
Nature communications 2019 Jan 8;10(1):69
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Datta P, Hendrickson B, Brendalen S, Ruffcorn A, Seo S
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Datta P, Allamargot C, Hudson JS, Andersen EK, Bhattarai S, Drack AV, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STXBP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human STXBP1. This antibody recognizes human,mouse,rat antigen. The STXBP1 antibody has been validated for the following applications: ELISA, WB analysis.
