Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- PAB2159 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2159, RRID:AB_1579043
- Product name
- PPP3CA polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PPP3CA.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The linker region joining the catalytic and the regulatory domains of CnA is essential for binding to NFAT.
Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis.
Regulation of NF-kappaB activation by protein phosphatase 2B and NO, via protein kinase A activity, in human monocytes.
Rodríguez A, Martínez-Martínez S, López-Maderuelo MD, Ortega-Pérez I, Redondo JM
The Journal of biological chemistry 2005 Mar 18;280(11):9980-4
The Journal of biological chemistry 2005 Mar 18;280(11):9980-4
Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis.
Shirane M, Nakayama KI
Nature cell biology 2003 Jan;5(1):28-37
Nature cell biology 2003 Jan;5(1):28-37
Regulation of NF-kappaB activation by protein phosphatase 2B and NO, via protein kinase A activity, in human monocytes.
Bengoechea-Alonso MT, Pelacho B, Osés-Prieto JA, Santiago E, López-Moratalla N, López-Zabalza MJ
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003 Feb;8(1):65-74
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003 Feb;8(1):65-74
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of PPP3CA polyclonal antibody (Cat # PAB2159) in mouse kidney tissue lysate. PPP3CA (arrow) was detected using the purified Polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PPP3CA polyclonal antibody (Cat # PAB2159) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)