Antibody data

Product number
BS60748 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PPP4R1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human PPP4R1
Description
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Protein phosphatase 4 (PP4) is comprised of different regulatory subunits that exhibit mutually exclusive interactions with the PP4 catalytic subunit, PPX. PP4R1, also known as PPP4R1 or PP4(Rmeg), is regulatory subunit 1 of protein phosphatase 4. It is ubiquitously expressed and can form a binary complex with PPX that negatively regulates the activity of HDAC3. PP4 is required for cell growth, nucleation and the stabilization of microtubules during cell division. This suggests that PP4R1 participates in the regulation of mitosis.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PPP4R1 protein structure - BS60748 shown in red.